Researchers Pinpoint Site For Petit Mal Seizures In Brain
... receive signals are normal in the mouse thalamus, suggesting the defect lies on the sending side of neural transmission. "Most people think of receptors as being important in receiving signals, but this result suggests we should be looking at the sending side of the neuron," Hosford said. Hosford has already ......imals, to San Francisco Bay in the past 150 years, suggesting that the bay is the most invaded estuary in the world. T. hadai's presence in San Francisco Bay is probably not the first time one of these tiny organisms has traveled around the world, the scientists say. It is likely that there are a number of int...Disease Resistance Mechanism Identified in Plants
...necrosis known to result from the resistance gene, suggesting that the products of the resistance and the avirulence genes were interacting directly. "These findings set the stage to allow us to genetically engineer disease-resistant crops," Brian Staskawicz, a biologist at UC-Berkeley concludes....Mechanism For Disease Resistance Identified In Plants
...necrosis known to result from the resistance gene, suggesting that the products of the resistance and the avirulence genes were interacting directly. "These findings set the stage to allow us to genetically engineer disease-resistant crops," Brian Staskawicz, a biologist at UC-Berkeley concludes....Molecular Imposter Rebuts Long
...c, it was insertedcorrectly nearly all the time -- suggesting that base shapeis more important than hydrogen bonds in ensuring accurate DNAreplication. "Most biochemistry textbooks cite hydrogen bonds as theprimary reason that DNA is copied accurately," says Kool, aprofessor of chemistry. "Because of this ...Altered Genes, Altered Metabolism--Longer Life?
...ly restricted rats which have anextended lifespan, suggesting that this mechanism in humans may have thepotential for slowing down aging. The National Institute on Aging, one of the 18 Institutes which make up theNational Institutes of Health, leads the Federal effort supporting basic,clinical, epidemiological ......ficant quantities in the extracellular free virus, suggesting that itmay be crucial in the early stages of infection by the virus. Now, researchers at the University of Pennsylvania Medical Center reportthat Vpr, the protein product of vpr, blocks the production of cytokines in thecells first infected b...Scientists Find New Trigger For Nerve Cell Death
...e number of cellsthat died after serum withdrawal, suggesting that potassium loss is indeed atrigger for apoptosis. Reducing potassium loss by increasing the amount of potassium in thesolution bathing the cells also prevented apoptosis. This protective effect wasseen even in the presence of a substance ...Herpes Virus Strain Identified As A Trigger In Multiple Sclerosis
...ent. This is the first publishedlarge-scale study suggesting an association of a human herpes virus in thedisease process of MS. In the study, more than 70 percent of patients with the relapsing-remitting formof MS showed an increased immune response to human herpes virus-6 (HHV-6) andapproximately 35 percent ...Biological Clocks No Longer Found Only In The Brain
...bbed and flowed autonomously in response to light, suggesting that circadian rhythms likely regulate a fruit fly's sense of smell, much as they influence light and pain sensitivity in mammals. While the authors raise the possibility that this evidence challenges the current notions about the role of the br...MIT Biologists Identify Aging Mechanism
...ary for life. A WONDROUS PARADOX Armed with data suggesting that the accumulation of ERCs may be the aging clockitself, the researchers wondered, what set the fatal accumulation in motion?What, as Professor Guarente inquired above, could "set the clock early (so) thealarm rings early"? Their experimental resu...Doublecortin : A Novel Gene Involved In Cortical Development
...lecortin was strongly expressed in thefetal brain, suggesting its implication in the early stages of corticaldevelopment. The discovery of this gene has two important implications. First, it advancesour understanding of the molecular mechanisms involved in brain development.Second, it provides a tool for prena...Infants, Toddlers Should Not Restrict Fat Intake, Experts Say
...re getting too little fat in their diets. They are suggesting new dietary recommendations for children as old as age 5 and changes in the makeup of infant formulas. "The scientific community is focused in one direction, and that is reducing dietary fat in all individuals," Watkins says. "But trying to adapt fat...SFSU Biologist Deciphers Desert Animals' Whistles And Drumbeats
...en they hear the faster whistles and the stomping, suggesting that these signals are perceived as signs of danger too. By contrast, kangaroo rats don't respond to a neighbor's foot stomps, supporting the conclusion that these solitary rodents don't use stomping to warn each other of an approaching predator. ...Reagent Strips Not Sufficient In Detecting Bacteriuria In Early Pregnancy
... Asymptomatic bacteriuria (bacteria in the urine suggesting illness, which is unnoticed by the patient) is a potentially serious clinical condition in pregnant women. In a paper in this week's BMJ, Tincello and Richmond note that early antenatal urine screening should identify all cases to ensure adequate tr...Long-Standing Puzzle Of Immune System Is Solved By UCSF Researchers
... containing Pms2 compared to micelacking the gene, suggesting that Pms2 somehow acts differently to play anactive role in hypermutation of these genes in B cells. Prior to cell division, when a cell duplicates its geneticmaterial, the double-stranded DNA helix unzips and each strand serves as atemplate...Pitt Researchers Find Way To Block Cellular Growth Pathways And Inhibit Tumor Growth
... produced in abnormally highlevels by tumor cells, suggesting that they play an important role inmaintaining cancer growth. In their research, Dr. Grandis and her colleaguescreated genetic sequences that block the translation of the genes for TGF-" andEGFR into TGF-" and EGFR proteins. The investigators inject...Tiny Worm Reveals Workings Of Suspected Tumor Protein
... This finding fits with vertebrate studies suggesting that most embryoniccells tend to become neurons by default. Specific signaling events are necessaryto coax cells to mature into other cell types, much like it takes activesignaling to dissuade a prospective male embryo from its inherent tendency tobe...New Look At How Cells Move Could Shed Light On Tumor Growth
...found higher calcium levels at the rear of a cell, suggesting a possibleregulatory role. In a paper accepted for publication in the Journal of Cell Biology, researchersalso found that, depending on the type of integrins present on the surfaceof cells, cells can either move apart easily or become stuck to each...First Evidence That Localized Arthritis Gene Therapy Heals Distant Diseased Joints
...safety of this approach and yield preliminary data suggesting whether or not it works at the tissue level. This clinical trial differs from the rabbit study in several ways. The gene used is for interleukin-1 receptor antagonist (IL-1Ra), a protein that fastens to the IL-1 receptor on synoviocytes, thus block...