Gene discovered for primary pulmonary hypertension
...e of oral contraceptives, cocaine, or the appetite suppressant drugs, phentermine-fenfluramine (phen-fen). Phen-fen is no longer available in combination due to these effects. People with autoimmune disease or late stage AIDS can also develop PPH. Although the majority of PPH cases do not appear to have a pri...Scientists identify gene that causes fatal lung disease
... PPH or PPH occurring in association with appetite suppressant use, Loyd said. In 1997, in Nature Genetics, Loyd and the research group reported the first identification that a gene caused PPH in families."It's especially exciting to us because a lot of work about TGFb has been previously done at VUM...UCSF study suggests novel factor could contribute to adult obesity
... serotonergic transmission, including the appetite suppressant fenfluramine and the depression-treating serotonin reuptake inhibitors. In prior work, Tecott's team found that the appetite-suppressant effects of fenfluramine were reduced in the 5-HT(2c) receptor mutant mice, implicating the receptor as a target f...UCLA study uses genetic profiling to distinguish types of leprosy
...hat may provide potent anti-inflammatory or immune suppressant properties. These findings offer more insight into the development of leprosy, as well as new approaches to treat diseases in which the immune system causes tissue damage. "This study is an important milestone in the new science of using genetic prof...