Drug stops blinding blood vessel growth in mice
...ted maculardegeneration include laser treatment or surgery to eliminate the abnormal bloodvessels. But, in addition to risks associated with surgery, the treatments donothing to treat the underlying stimuli for blood vessel growth, Campochiarosays. "As a result, the blood vessels tend to come bac...Procedure, new apparatus may allow relief from incontinence
...k, a colorectal surgeon and assistant professor of surgery at UTSouthwestern Medical Center at Dallas. She is overseeing UT Southwestern'sparticipation in a multicenter trial of a new artificial bowel sphincter device. UT Southwestern is one of 14 centers participating in the Food and DrugAdministration-spon...Gene therapy could treat diabetic incontinence, suggest early studies at University of Pittsburgh
.... Chancellor, M.D., associate professor ofurologic surgery at the University of Pittsburgh School of Medicine. The UPMC team capitalized on herpes' natural ability to infect nerve cells. They placed the gene for NGF inside a herpes vector modified to be harmless. Then the team injected the NGF gene-bearing h...Cystic fibrosis gene undetected in screening of infertile men
...iation. Dr. Keith Jarvi, an associate professor of surgery at the University of Torontoand staff urologist at...reening for cystic fibrosis. "Dramatic advances in surgery and in vitro fertilization have given many menwith infertility an opportunity to father children, wh...Cardiac surgery patients at higher risk
...as, including atrial fibrillation, during andafter surgery doubled when a patient's serum potassium level fel... considered on acase by case basis for all cardiac surgery cases. "We hope these results will change the impression that mild decreases inpotassium are within ...International biotech firm to locate in Southwest Virginia
...at patients with hemophiliaand control bleeding in surgery and trauma. In making this announcement with Virginia Governor James Gilmore, George J.M.Hersbach, chairman of Pharming Healthcare Inc. and president and CEO of PharmingGroup NV, said "We have selected western Virginia for this phase of PharmingHeal...Unique web site provides live access to laboratory research
... assistant research scientist in the department of surgery at UF'sCollege of Medicine, and researchers from the University of Maryland areusing the NMR spectrometer to determine if doses of zinc can slow or stopthe growth of prostate cancer cells. "In order to improve survival rates and reduce medical costs...Young rats challenged as model for blood vessel response in older people
...flow, which can occur during heart attack, stroke, surgery orother circulatory problems. When circulation slows or ceases and then isrestored, a condition known as ischemia-reperfusion or I/R, inflammation andswelling can occur. Harris notes that when I/R-induced inflammation and swellingoccur in the brain o...Gene therapy trial using cold virus to begin at UK
...s (common cold virus) in combination with standard surgery andchemotherapy to treat ovarian cancer that has s... Standard treatment for ovarian cancer is surgery followed by six monthsof chemotherapy. Two major types of genes are abnormal in human can...Scientists clear hurdle in effort to destroy experimental brain cancers with viruses
...cca, Harvard Medical School associate professor of surgery at Massachusetts General Hospital and hiscollaborators found that the drug cyclophosphamide suppressed the immune system's antiviral response. Inhibiting this responseallowed a modified strain of herpes simplex virus to reach the brain tumors, enabli...New gene therapy found safe for treating coronary heart disease
...engart, M.D., associate professor ofcardiothoracic surgery at Weill Medical College of Cornell University, Ne... Three of the 15 patients who underwent bypass surgery died within 145days of their operations. None of the deaths resulted from the gene therapy. There w...Growth factor may determine who grows new blood vessels that protect against heart attacks
...crease the blood flow in the heart, through bypass surgery orballoon angioplasty. "We are now working out the molecular mechanisms that will allow for thedevelopment of a drug that would increase VEGF production in those patients whoproduce low levels of it and allow them to grow their own collateral bloodve...Scientists suggest genetic shutdown links estrogen, heart disease
...t tissue normally discarded during coronary bypass surgery orcoronary atherectomy, a "roto-rooter"- like process that clears plaque fromcoronary arteries. They used specialized molecular probes to identify "normal"ER genes and those that were methylated. "Many studies show women on hormone replace...LOS ANGELES (Sept. 7, 1999) -- The cardiothoracic surgery team at Cedars-SinaiMedical Center has recruited a...d clinical instructor of cardiothoracic transplant surgery at theUniversity of Pittsburgh, one of the nation's most respected heart transplantcenters. While th...Mayo Clinic study implicates fungus as cause of chronic sinusitis
... per patient. In a subset of 101 patients who had surgery to remove nasal polyps, theresearchers found eosinophils (a type of white blood cell activated by thebody's immune system) in the nasal tissue and mucus of 96 percent of thepatients. The results, the researchers say, clearly portray a disease process...NIAMS funds multicenter study of surgical vs. nonsurgical treatment of back pain
... Evaluative Clinical Sciences, and professor of surgery at Dartmouth MedicalSchool. Participating centers include: Case Western Reserve University (Cleveland, Ohio), DartmouthMedical School (Hanover, N.H.), Emory Spine Center (Decatur, Ga.), the Hospital for Special Surgery (NewYork, N.Y.), Rothma...NIAMS funds the North American Spondylitis Consortium
...d degree, antibiotics. In cases of spinal fusion, surgery is used tostraighten the back and allow a person to stand upright; however, restoringoriginal flexibility and function is not possible. There is no cure. "Recent familial studies show genes other than HLA-B27 have possibleimplications for AS, " said...... For many women under 40 with breast cancer, surgery to remove thecancerous lump and accompanying radiation seem the best way to get rid of thedisease and preserve the natural breast. But for women who carry a damagedversion of BRCA1 or BRCA2, genes predisposing them to breast cancer, suchtreatment may...Researchers solve vision mystery
...or of the HSC Eye Genetics team, who performed the surgery on thebabies. "When the cataracts are dense it's l...e in 1,000 to 4,000 babies born with cataracts. If surgery isdone too late then the brain may not learn to use the vision in that eye. Withsuccessful early in......inst colitis, said Nigel Bunnett, PhD,professor of surgery and physiology at the University of California, Sa...ool; and Eileen Grady,PhD, assistant professor of surgery at UC San Francisco. The research was funded by the National Institutes of Health, the Crohn's andCo...