Fruit fly model could explain how mosquitoes carry malaria: new drugs and vaccines on the horizon
...ifying factors that are critical to the parasite's survival inside the mosquito, these experiments may lead scientists to drugs that prevent the parasite from growing in the mosquito. Weak points in the parasite's lifecycle could be potential targets for anti-malarial drugs and vaccines. Because parts of the...Compound that switches off appetite in mice discovered by Hopkins scientists
...our metabolism slows down after a few days: It's a survival mechanism that sabotages many diets. We see this in fasting mice. Yet metabolic rate in the C75-treated mice doesn't slow at all." C75 is a small member of a family of organic molecules called butyrolactones. It's a novel molecule purposely created b......rts. To confirm whether OUES can help/predict survival among heart disease patients, Hollenberg hopes to collaborate with researchers who have large numbers of these patients who have performed exercise tests. "The question is, can we use it as a more accurate predictor of mortality in heart disease?" h......he biochemical pathway that controls apoptosis and survival of cancer cells," said W. Joseph Thompson, Ph.D., vice president of research at Cell Pathways and lead author of the publication. "Our initial data indicates that increased PDE5 expression, and in some cases PDE2, occurs in precancerous and cancerous...Extra oxygen improves survival odds for climbers on Mount Everest, K2
...hat climbers using supplemental oxygen have higher survival rates might reflect the benefits of extra oxygen in reducing the physical and mental deterioration that is inevitable at extreme altitude," Huey said. "But our data don't necessarily imply cause and effect. Another explanation is that climbers using ...Gene discovered for primary pulmonary hypertension
...ntravenous or inhaled medication, and they prolong survival but do not cure the disorder. Sporadic cases of PPH are more common than familial cases, and their development can be associated with several things including: pregnancy, hypothyroidism, and the use of oral contraceptives, cocaine, or the appetite ...Two NHLBI studies confirm finding of gene in primary pulmonary hypertension
...mon. Before the availability of these treatments, survival following diagnosis of PPH was only 3 to 5 years. Even with treatment, life expectancy for PPH patients is very limited. The NHLBI created the first PPH Patient Registry in the world in 1981 to gain an understanding of the natural course of PPH....Biologists find Peruvian plants inhibit growth of TB bacterium
...from huge numbers of pathogens and insects. Plant survival is dependent on their genetic ability to produce a wide range of these defensive compounds. Lewis believes he found such a high anti-TB reactivity across the broad range of plants because the plants have shared sensitivities that "allow secondary me...Gene 'shaving' could help doctors predict the efficacy of cancer treatments
...ing genes whose expression correlates with patient survival is an obvious challenge." The team used more tha...have been able to identify the patient's chance of survival based on the genetic information in the sample tumor. Gene shaving will allow researchers to analy...... "This model indicates that the key to extending survival time for people with AIDS is to minimize the number of CD4 cells exposed to signals in the lymph system which lead to apoptosis or cell suicide," says Miles W. Cloyd, Ph.D., a professor of microbiology at the University of Texas Medical Branch at Gal...Wolves in Yellowstone may aid aspen recovery
...tone Park. The study is comparing aspen growth and survival rates both inside and outside the territories of Yellowstones wolf packs. The researchers will acquire data on the amount of elk use of those areas and its effect on aspen growth....Cellular membrane changes associated with acclimation to cold
...er 21, 2000, issue of Nature (1). Hibernation is a survival strategy that some mammals use during the winter to cope with shortages of food supplies and cold temperatures. When a mammal prepares for hibernation, its body temperature lowers to near-freezing temperature. For brief periods, the hibernating mam...UC Berkeley demographer finds first evidence that maximum age at death in humans is rising
...lmoth's data show that the main cause is increased survival after age 70. Earlier in the century, the lengthen...he spurt upward in 1970, Wilmoth's data shows that survival after 70 was due overwhelmingly to improved medical practice concerning heart disease, stroke, smoki...Prions may play crucial role in evolution.
... hold the key to a major mystery in evolution: how survival skills that require multiple genetic changes arise all at once when each genetic change by itself would be unsuccessful and even harmful. In a study in the September 28, 2000, issue of Nature researchers at the Howard Hughes Institute at the Unive...Ringling Bros. announces four Asian elephant pregnancies at Center for Elephant Conservation
...sian elephant calf that is born today helps ensure survival of the species tomorrow. The newly-expecting pachyderm parents are 25-year old Icky, 33-year-old Mala, 33-year-old Sally and 25-year-old Alana. All four were bred with Charlie, a 30-year old Asian bull elephant who also makes his home at the CEC. ...Brain size in premature infants significantly smaller than full-term babies
... one percent of all births in our country, and the survival rate for these infants is well over 80 percent. But the incidence of handicap is high." "By age eight years, over 50 percent are in special education or receiving extensive resource room help," she said. "One-fifth have already repeated a grade of ...Media Advisory 2: Fall Meeting: Abstracts, press conferences, press registration
... The science of carbon sequestration Microbial survival and interaction with minerals The impact of volcanic activity on Earth's atmosphere Preliminary results of the Hawaii drilling project Volcanology in 2010: what will have changed? Predicting submarine mass failures and tsunami hazards ***...Boys still 'weaker' sex at birth despite improvements in treatment
...is weeding out the less fit males, so ensuring the survival advantage of the next generation, is unclear, say the authors. "The biological mechanisms contributing to the male disadvantage or female advantage have not been elucidated. Until science can rationalise the male and female circumstances, nature's in...Impurities in biominerals reveal key to understanding climate change, will lead to novel materials
... the calcium carbonate minerals so critical to the survival of many organisms. However, the actual mechanism by which magnesium alters calcium carbonate growth has remained controversial for the past 25 years. Davis and his colleagues resolved this long-standing controversy. "By comparing molecular-scale meas......he molecules responsible for metabolism - then its survival is in jeopardy. Therefore, additional warming could create serious problems for both snail species.`` Ever northward These experiments may help to explain why so many marine invertebrates, once common in Monterey Bay, have become less abundant ther...