JCI table of contents, 16 August, 2004
...tor promotes intestinal cholesterol absorption and susceptibility to cholesterol cholelithiasis AUTHOR CONTACT: Martin C. Carey Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA Phone: (617) 732-5822; Fax: (617) 730-5807; E-mail: mccarey@rics.bwh.harvard.edu View the PDF of this article a...Genes can influence both alcohol consumption and dependence
...dependence are closely related, but the causes of susceptibility to the two may be different. New research has foun...ol dependence are closely related, the causes of susceptibility to the two are not necessarily the same. A study in the August issue of Alcoholism: Clinical & Exp...Genes may be central to cocaine addiction
... new research pathway to understanding how genetic susceptibility to addiction interacts with environmental factors to cause addiction. Studies by other researchers had suggested that the proteins produced by the Homer genes might play a role in cocaine addiction. Members of the family were known to be activated by...DNA variations surprise researchers
...umber of these genes was associated with increased susceptibility to pancreatic diseases or cancer. This would allow us to use these LCVs as disease markers." The information on identified LCVs has been collated into a publicly accessible database called the Genome Variation Database (http://projects.tcag.ca/variat...Virtual counselor supplements traditional genetic counseling
... decide whether or not to have genetic testing for susceptibility to breast cancer." Most women concerned that they are at risk for developing breast cancer are referred to genetic counselors who can assess a women's risk, advise her about testing and explain the options. But, with only about 400 genetic co...Location of potential familial lung cancer gene discovered
...es of Health (NIH), identified a major lung cancer susceptibility region on a segment of chromosome 6. The findings ...searchers found strong evidence that a lung cancer susceptibility gene or genes is co-inherited with a genetic marker on chromosome 6. Markers on chromosomes 12, 14,...Researchers uncover surprising degree of large-scale variation in the human genome
...ding to the study, a relationship between CNPs and susceptibility to health problems such as neurological disease, cancer, and obesity is an intriguing possibility. The study revealed considerable structural variation in the human genome, most of which was not previously apparent by other methods of genomic analysi...Long-term heart damage may result from constant confrontation and defeat
...ehavioral changes may ultimately produce increased susceptibility to psychosomatic disorders when the brain impacts ...turn represents a substrate predisposing to higher susceptibility to arrhythmias. Those who supervise individuals in a constant-stress environment should consi...Anxiety during pregnancy affects child behavior
... anxiety during a woman's pregnancy on her child's susceptibility for attention deficits, hyperactivity, acting out ...ld's biological system, thus increasing the fetus' susceptibility for such disorders. We evaluated data collected on 71 normal mothers and their 72 first-born childre...Skin condition linked to genetics in Caucasian and Chinese populations
...ndition called psoriasis, revealing a link between susceptibility to psoriasis and regions on chromosomes 6p21 and 4q28-q31. According to the study, psoriasis, a chronic inflammatory dermatosis, is believed to be inherited and triggered by environmental, as well as genetic, factors. It affects "2%-5% of the Cauca...OHSU scientists find gene influencing drug withdrawal
...t the level of behavior," Buck said. To determine susceptibility to withdrawal in mice, researchers measured the se... seizures. However, Mpdz does not regulate seizure susceptibility in general because its status is genetically correlated with seizures induced by some, but not all, ...Articles on forest fire risks published in BioScience
...te that invasive plants can dramatically alter the susceptibility of a forest to fire. Previous assessments have con...ous additional ways that invasions can affect fire susceptibility and note that many of them are not widely recognized. Invaders can both increase and decrease flamma...New York City study shows newborns more susceptible to pollution than their mothers
...ronmental Health and the study team leader. "Fetal susceptibility to DNA damage from air pollution, including motor vehicle emissions and secondhand smoke, has important implications for cancer risk and developmental problems. And it underscores the importance of reducing levels of air pollution in our city." A pre...Study sheds new light on genetic risk for Parkinson's disease
...g cholesterol, through the body."APOE-4 is a major susceptibility gene for sporadic and familial Alzheimer's disease.... These genotypes' influence on Parkinson's susceptibility is thought to be modest, as a number of factors may contribute. Thus, the number of subjects in an i...Study helps explain island populations' susceptibility to exotic diseases
...systems "and this may be the explanation for their susceptibility to invasive diseases," Foufopoulos said. The team found that larger islands with larger bird populations harbor more native parasites and diseases, because the number of parasites is directly dependent on the size of the population. Island size and ...Existing drug may prevent brain injury and seizures in newborns
...eizures induced by hypoxic encephalopathy increase susceptibility to seizure-induced neuronal injury later in life,"... hours after hypoxia-induced seizures also reduced susceptibility to seizure-induced damage later in life. "In human babies, pretreatment is not always clinically pra...Drunken worms reveal a genetic basis of alcohol response
...ay have direct relevance to our ability to predict susceptibility to alcoholism in humans." Download PDF | More from Neuron ...Thimerosal, found in childhood vaccines, can increase the risk of autism-like damage in mice
...ism, hypothesizing that the combination of genetic susceptibility and environmental exposure to mercury in childhood...ccines. Identifying the connection between genetic susceptibility and an environmental trigger for autism--in this case thimerosal exposure--is important because it m...Common worm provides insights into salmonella virulence
...he host that appear to confer either resistance or susceptibility to Salmonella. The researchers expect that these polymorphisms would also play a role in human disease. Other members of the research team were Duke's Jennifer Tenor, as well as Beth McCormick, Ph.D., and Frederick Ausubel, Ph.D., of Harvard Medical ...Male susceptibility to disease may play role in evolution of insect societies
...mong social insects, suggesting that a higher male susceptibility to disease has helped shape the evolution of the i...onnell and Beshers contend, puts males at a higher susceptibility to disease. The researchers, who are trying to understand the basis of social behavior in these cr...