NIH awards $20.7 million to make smallpox vaccine safer
...ork. "Our consortium will seek to understand their susceptibility and develop protocols that will allow them to be vaccinated against this potential bioterrorist threat."Erwin Gelfand, M.D., Chairman of Pediatrics at National Jewish, will conduct animal studies in association with the Animal Studies Consortium of t...Protein may reduce susceptibility to autoimmune disease
...ion of T cells and thus plays a role in preventing susceptibility to T cell-mediated autoimmune diseases. "The discovery of a new form of CTLA-4 was a completely unexpected result and demonstrates that the study of natural variation of genes altering autoimmune diseases such as type 1 diabetes can yield new insigh...Crop rotation may help wait out soil pathogen deadly to pumpkins
...es of crop and weed plants were screened for their susceptibility to P. capsici. Although 22 crop species succumbed to the disease, 14 did not. Mohammad Babadoost, a plant pathologist in the College of Agricultural, Consumer and Environmental Sciences, believes that rotating the 14 resistant vegetable varieties may...Analysis uncovers critical stretches of human genome
...very slowly for some other reason, such as lack of susceptibility to mutation, or "hyper-repair." But it is even harder to imagine a mechanism for that." Further studies, said Haussler, will involve not only more detailed comparisons of the conserved elements, but also laboratory studies exploring their functionali...Computer modeling targets epidemics, bioterror
...ission rate, weather patterns, peoples' individual susceptibility and social networks. The researchers will then introduce and evaluate the effectiveness of containment methods like vaccination, contact tracing and quarantine. They will initially focus on smallpox, dengue fever and West Nile virus, then will apply ...New research outlines public health consequences
...any of which significantly increased the subjects' susceptibility to bronchial spasms and asthma," said Landrigan. "These respiratory effects were most pronounced in subjects who were in or around the WTC buildings during the first 12 hours of the disaster." Previous studies have documented the acute traumatic c...John Sherris receives 2004 Abmm/Abmli Professional Recognition Award
...iving force behind the development of standardized susceptibility testing, culminating in the standardized disk diffusion test, now known as the Kirby-Bauer or Bauer-Kirby test. His achievements are recognized internationally, through his years of service with the World Health Organization's Expert Advisory Panel o...Technique plucks rapidly evolving genes from a pathogen's genome
...d on an idea by Plotkin, the team zeroed in on the susceptibility of codons to point mutations - alteration of a single DNA nucleotide - and the fact that not all point mutations have the same effect. A random point mutation in some codons is less likely to create a codon that codes for a different amino acid. For ...Dietary supplement shows promise for improving immune function in the elderly
...ed with important manifestations such as increased susceptibility to infection and cancer. Immune system response ...function is generally associated with an increased susceptibility to infections. For example, individuals with age-related declines in cellular immunity have an impai...Research finds lawn chemicals raise cancer risk in Scottish terriers
...overy that could lead to new knowledge about human susceptibility to the disease, according to Purdue University sci...lp physicians pinpoint genes in humans that signal susceptibility to bladder cancer. "The risk of transitional cell carcinoma (TCC) was found to be between four and s...Embryonic skin cells committed at an early age
... is also likely to have important consequences for susceptibility to environmental and/or toxic agents and cancer development. Cell populations that terminally differentiate at a fast rate likely provide a smaller target size than cells turning over at a slower rate. Conversely, more deleterious and uncontrolled ef......try is the first to identify a gene that increases susceptibility to autism in a broad population. Approximately 1 in 1,000 people have autism or autistic disorder. It appears to be the most highly genetic of all psychiatric disorders. If a family with one autistic child has another child the chance that this child...Gene-rich human Chromosome 19 sequence completed
... the development of more sensitive diagnostics for susceptibility to a wide array of important diseases. In time, with this information in hand, physicians will be able to tailor more effective individualized therapeutic strategies. Chromosome 19, at 55.8 million bases or letters of genetic code, although represen...Gene variants may increase susceptibility to type 2 diabetes
...studies as a likely location for a type 2 diabetes susceptibility gene, the teams identified four genetic variants, ...ombination with other yet-to-be-identified genetic susceptibility factors, together with certain environmental influences such as obesity and lack of physical exercis...Search for macular degeneration genes narrows
...- and now we are ready to begin the search for AMD susceptibility genes in earnest," says Swaroop, a professor of op...es where researchers can continue their search for susceptibility genes. Patients were recruited from the Kellogg Eye Center's clinical practice and consisted largel...Migraine mouse provides insight into neurobiology of devastating headaches
...ase of excitatory neurotransmitters, and increased susceptibility to cortical spreading depression (CSD), the phenom...cortical hyperexcitability results in an increased susceptibility for CSD and aura," explains study coauthor Dr. Arn M.J.M. van den Maagdenberg. The authors suggest t...ESA calls for interdisciplinary studies of GEOs
...populations, or their traits "could increase their susceptibility to predation and stressful environments," according to the paper. "Another concern is that GEOs will interbreed with native populations once released," said Allison Snow, lead author of the position paper and a professor at Ohio State University. "It...JCI table of contents, March 1 2004
...rosis Individuals with diabetes show an increased susceptibility for the development of accelerated atherosclerosis, however the root causes of this progression are not well understood. Some evidence suggests that insulin resistance, commonly seen in overweight individuals, is an important cause of both diabetes a......e and how genetic variation may play a role in the susceptibility of different strains to the disease. In addition to its tremendous economic value as a source of eggs and meat, the chicken is widely used in biomedical research. It serves as an important model for the study of embryology and development, as well as......ure to environmental factors suggests that genetic susceptibility may be important. Highly penetrant genes or mutations probably only account for a small proportion of cases. What is more likely is that cancer develops as a result of exposure to a risk factor in a genetically susceptible individual." She said that ...