DFG establishes 14 new research units
...Factors of Tumourigenesis", which will examine the susceptibility of organisms to develop tumours. The objective of the unit is to research the factors affecting susceptibility. The transplantation of pig organs into humans is a realistic option for overcoming the worldwide shortage of organ donors. The DFG is now ...Drug addiction, learning share common brain protein
...w genetic approaches for assessing an individual's susceptibility to drug addiction. They also illuminate the comple... of PSD-95 might lead to differences in individual susceptibility to drugs of abuse, he suggested. The gene might therefore represent a useful marker for measuring su...Scripps scientists say genetic mutation doesn't protect against HIV and plague
...t the CCR5 32 mutation. There was no difference in susceptibility between the two groups, says Mosier. The possibility still exists, says Mosier, that the CCR5 32 mutation arose due to the influence of some other disease that was prevalent in the Middle Ages, such as smallpox. Mosier plans to address this possibil...Researchers-again-pinpoint why stress kills
...earchers set out to ascertain whether an increased susceptibility to life-threatening cardiac arrhythmias in depress...acts that would ordinarily be pleasurable) and the susceptibility to ventricular arrhythmias in rats. This entailed the employment of aconitine, in rats exposed to CM...Finding may help eczema sufferers tolerate smallpox vaccine
...gives us a window into the possible reasons behind susceptibility to infections, and may help us better predict and control reactions to the smallpox vaccine or similar agents," said Gallo. Gallo collaborated with a team at the National Jewish Medical and Research Center and Colorado Health Sciences Center that in...Ancient DNA mutations permitted humans to adapt to colder climates, UCI researchers find
...ress will determine an individual's aging rate and susceptibility to a variety of diseases such as diabetes, memory loss, forms of deafness and vision loss, cardiovascular disease, etc. If all the calories that an individual consumes are used in generating carbon dioxide, water and energy, little fuel is left over...California pistachio industry threatened by potentially devastating disease
...lar fungus. "Because of the California pistachio's susceptibility to this fungus, panicle and shoot blight has the potential to reach epidemic levels in pistachio orchards in only a few years," he said. To prevent such epidemics from occurring, and since some resistance to the disease exists in the present Pistaci...DNA registry to study links among genetics, environment, disease
...dy the link among environmental exposures, genetic susceptibility and human disease. Eventually to include 20,000 patients at various UNC medical facilities, the Environmental Polymorphism Registry will be unlike the many anonymous DNA repositories that have developed since the advent and recent completion of the...A new direction for psoriasis research?
...ding of polymorphisms in the VEGF gene relating to susceptibility to psoriasis reinforces the concept that angiogene...differentiation, and angiogenesis) might determine susceptibility to psoriasis." The Young et al paper is called "Single Nucleotide Polymorphisms of Vascular Endothel...Gene differences may alter susceptibility to multiple sclerosis
...n. An unidentified environmental agent and genetic susceptibility are thought to play a role in its onset. Earlier work led by Liu showed that the CD24 protein is required for the development of an MS-like disease in mice, experimental autoimmune encephalomyelitis. Mice missing the protein did not develop the dise...The dopamine receptor D1 gene and ADHD: A piece of the genetic puzzle?
...a particularly strong candidate for involvement in susceptibility to ADHD. To test this, the authors investigated the inheritance patterns of four DNA changes (situated at various positions across the DRD1 gene) in a large sample of small families, each having at least one child diagnosed with the disorder. These ...Breast cancer susceptibility genes play role in DNA repair
...x are good candidates for additional breast cancer susceptibility genes." Shiekhattar and his colleagues determined that the BRCC protein complex acts as one large regulatory enzyme. They discovered that one target of BRCC is a protein familiar to cancer researchers called p53, a potential cancer-promoter if left u...Severe kidney disease in blacks linked to genes on two chromosomes
... older people. This indicated, they reported, that susceptibility in the younger group likely was related to the uni...ed the same region on chromosome 18 as harboring a susceptibility to kidney damage from type 2 diabetes in the Pima tribe of Native Americans and in Turkish families....With flu season coming, don't forgetexercise?
...ice were used for each dependent variable: in vivo susceptibility to infection (n=24 per group), macrophage anti-vir...hesis that moderate exercise training can decrease susceptibility to induced respiratory infection in mice. These data also provide evidence of a role for macrophages...Three genes linked to psoriasis susceptibility identified on chromosome 17
...ers of psoriasis patients. Several other psoriasis susceptibility genes are expected to be identified in the months ... are going to identify a large number of psoriasis susceptibility genes," Dr. Bowcock said. "These will be important building blocks toward finding a cure in the futu...GAD2 as a candidate gene for obesity
...ome-wide scans of a chromosomal region linked with susceptibility to hone in on a new candidate gene for obesity. The same group had previously found strong linkage between a region of chromosome 10 and obesity. GAD2, one of the genes in the region, codes for an enzyme that catalyzes the production of a neurotransm...Ethical guidelines needed before 'nutrigenomic' groceries come to market
...enetic testing may only be able indicate increased susceptibility to rather than certainty of future disease, the pa...ation "As more is learned about individual genetic susceptibility to disease, information from genetic tests may become increasingly attractive to outside parties who...Poor prognosis linked to BRCA1 mutations
...ne is mitigated by chemotherapy. The breast cancer susceptibility genes, BRCA1 and BRCA2, were identified over eight years ago, but the best way of treating women who develop hereditary breast cancer associated with mutations in these genes is still not clear. A team of researchers from McGill University in Montre...Gene mutation responsible for Chrohn's disease inflammation identified in Temple study
...ave found several genes that indicate an increased susceptibility to Crohn's disease, the Temple study went a step further and explored the role of genetics in causing the inflammation that characterizes the disease. Specifically, Temple researchers identified a genetic mutation that involves one of the proteins ...NIH funds 'Breast Cancer and the Environmental Research Center' at Fox Chase Cancer Center
...e pathways that are responsible for modulating the susceptibility or resistance of the mammary tissue to carcinogenesis," explained Russo. Dr. Mary Wolff and her colleagues at Mt. Sinai will investigate risk factors for pubertal milestones in young African American and Hispanic girls, specifically for age at first ...