Tag: "susceptibility" at biology news
Enzyme could aid cancer fight
...t may play a significant role in reducing people's susceptibility
to serious diseases such as haemophilia, cystic fibrosis and cancer. Teams at Cardiff University, Wales, and the University of Edinburgh, Scotland, who discovered a gene repair mechanism called the MBD4 enzyme in 1999, have now found that gene mutati...
Stem cells could determine how long we live
... formal link between regions controlling stem cell susceptibility
and regions thought to be involved in longevity," says Jan Vijg of the University of Texas Health Science Center in San Antonio. But it's only a correlation, not a definite link, he says....
Genome Therapeutics, University of Southampton and Schering-Plough identify novel asthma gene
...SE: SGP) describe the identification of a specific susceptibility
gene linked to asthma. A complex disorder with bo...n an outbred population, the gene linked to asthma susceptibility
is known as ADAM33. ADAM33, a member of the protease sub-family known as metalloproteases, was iden...
Transmission of drug-resistant HIV on the rise
... be determined by phenotypic testing to assess the susceptibility
of the virus to drugs in vitro. Virus that grows despite the presence of a drug is resistant to that drug, which means that it is less susceptible, but not impervious, to its effects. Using phenotypic testing, the researchers found a dramatic decreas...
Marijuana receptor gene abnormality in schizophrenia
...at 6q14-q15, which was included in a schizophrenia susceptibility
locus, 6q13-q26, revealed by Cao et al using two i...alleles or genotypes of the CNR1 gene may confer a susceptibility
of schizophrenia, especially of the hebephrenic type. The hebephrenic type schizophrenia, which has ...
Sex-specific genes for depression
...ense efforts by many investigators to identify the susceptibility
genes in the chromosomal regions that are confirme...otyping markers in chromosomal regions that harbor susceptibility
genes may provide more immediate advances in the treatment of major depression. For example, indivi...
Warmer world will be a sicker world, say scientists
...ission is longer. Warmer summers may increase host susceptibility
todiseases due to thermal stress, particularly in the oceans. Marine bacteriaand fungal growth rates are positively correlated with increasingtemperature. Some examples of disease outbreaks and their climate related links include: Expanding Range ...
Rats depleted of salt become sensitized to amphetamine, show unusual growth of brain cells
...on their history. Some people may have a life-long susceptibility
to these kinds of things. We also need to know why these drugs are so powerful and what systems they are taking advantage of that didn't evolve naturally." In the study, the researchers first gave a group of rats diuretics to deplete them of salt. ...
APS announces the winners of its 2002 Postdoctoral Fellowship in Physiological Genomics
...arch focus is identifying the gene responsible for susceptibility
to gallstones. Brian R. Wamhoff, Ph.D. University of Virginia Topic: Dr. Wamhoffs research focuses on the gene expressions and molecular mechanisms of smooth muscle cells associated with arterial hardening and vascular disease. The aim of this progr...
Association found between anthrax vaccination, medication and health problems of Gulf War veterans
...sely affect the health of individuals with genetic susceptibility
to such combinations." Schumm noted that their research confirms results reported previously by British, Canadian, and other U.S. research teams with respect to vaccinations and pyridostigmine bromide consumption. He is working on a critique of a rep...
Search for schizophrenia genes takes an unplanned turn
...t studies had suggested that genes associated with susceptibility
to schizophrenia would be found on the "q" or long arm of chromosome 1, a region separated from the short arm, known as "p." In their study, Pulver and colleagues searched for associations between genetic markers on chromosome 1 and schizophrenia in...
Children in lower socio-economic backgrounds at high risk for type-2 diabetes
...new hormones involved in obesity and is related to susceptibility
to non-insulin dependent (type 2) diabetes). A new study offers the first findings regarding adiponectin levels in children and their correlations to measures such as body composition and fitness and other obesity related risk factors. The authors o...
Understanding our ape 'cousins:' chimpanzee genetics may shed light on human diseases
...out the genetics underlying medical traits such as susceptibility
to AIDS, malaria, and Alzheimer's disease, say the Science researchers, led by Svante Pbo of the Max-Planck-Institute of Evolutionary Anthropology in Leipzig, Germany. The differences between humans and their closest relatives are more a matter of ...
Mitokor publishes human mitochondrial genome sequencing study - American Journal of Human Genetics
...w changes in mitochondrial DNA sequence can affect susceptibility
to disease. Mitochondrial genetics is improving our understanding of human evolution and prehistoric migratory patterns. In addition, mitochondrial sequence variation has been implicated as a causative or contributing factor in a number of human di...
Progress in the genetics of autism
...ggest chromosome 7q as a likely host for an autism susceptibility
locus (AUTS1). The authors follow a positional candidate gene approach to identify the gene in question and report the analysis of four adjacent genes localized to a 800-kb region in 7q32 that contain an imprinted domain a previously uncharacterize...
Osteoarthritis and genetic link
...in the April 2002 issue of Arthritis & Rheumatism, susceptibility
factors are likely specific for arthritis and could provide clues for new approaches for diagnosis or treatment. "As part of the complex etiology of the disease, there is an increased recognition that a genetic component plays an important role,"...
Pitt researchers find men and women have different genes behind depression
... chromosomal regions that harbor genes that affect susceptibility
to severe depression, the second leading cause of ...ense efforts by many investigators to identify the susceptibility
genes in the chromosomal regions that are confirmed. The identification and characterization of thes...
Biological evidence can persuade people to change unhealthy habits
...noxide levels (resulting from smoking) and genetic susceptibility
for lung cancer were twice as likely to attempt to...lesterol level, carbon monoxide level, lung cancer susceptibility
genes, depressed breathing function and other pulmonary symptoms and physical fitness. The studies e...
Researchers find evidence of genetic susceptibility
...tistically strong, indicating there may be several susceptibility
genes that underlie the genetic basis for AN. The ...the first genetic linkage study to detect specific susceptibility
loci for anorexia nervosa and we are excited about the possibility of identifying the particular gen...
Symptoms of illness less severe in hamsters during winter, study finds
... may affect the occurrence and susceptibility
to various diseases, as well as the severity and duration of illness in humans. "We need to have a better understanding of the mechanisms that underlie the interaction of the environment and...
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