Rockefeller scientists identify 'natural' proteins that push stem cells to produce hair, not skin
... become skin epidermis. The Rockefeller scientists suspected that beta-catenin and Lef-1 worked together to produce changes in the stem cell that pushed it to "morph" into hair, but they didn't know how, at that time. Proof of their findings came when the scientists altered genes in experimental mice to over p...First sightings of individual proteins as they fold
...he results verify what theoretical scientists have suspected for nearly a decade that protein molecules vary in the routes they take to the same folded shape and form numerous intermediate shapes on the road. The belief that had prevailed earlier was that one distinct route would dictate each shape. In the pa...'One-stop' approach works well for cervical cancer prevention
...bnormal tissue. Women with more advanced lesions, suspected cancers or other problems were referred to specialists. A year later, 94 percent of the women treated had no signs of any precancerous lesions. In addition, nearly 98 percent had recommended testing to others and nearly 95 percent said the treatmen...Receptor could be target for cancer therapy
...P2 receptor to promote cancer growth. Because they suspected a difference in immune system response, the investigators compared the function of various types of immune cells. A series of experiments demonstrated that white blood cells called T cells were normal in number and function in both wild-type and EP2...Tapeworm's chemical trick could make drugs more effective
... growing presence of drugs in the environment. The suspected sources are medicines that are not completely metabolized by the humans and animals they are administered to. "If we could halve the dosage, we could lower the percentage of nonabsorbed drug that ends up in the environment," says Oaks. The work done ...Stanford research points to chance as cause of genetic diseases in Ashkenazi Jews
...ve advantage for those mutations." Researchers had suspected that lysosomal storage diseases may be similar to sickle cell anemia, in which people who carry two mutated copies of the gene have a disease, but those who inherit one copy of the mutation are protected against malaria. Those people - called carrier...Metal ions may play big role in how we sense smells
...of their structure). Inorganic chemists have long suspected that the olfactory system involved metal ions. On...scientists found an uncommonly long loop that they suspected contained the binding site for a metal ion. To test their theory, the researchers created synthetic ...Drug tested for HIV prevention in Baltimore
...irapine is not used to prevent HIV infection after suspected exposure (such as in health care workers or rape victims). The three much-lower doses tested were chosen to spare the liver, yet keep blood levels of the drug high enough to potentially provide a benefit. Participants were divided into three groups: ...Protein linked to movement disorders
...diseases in which misfolded protein aggregates are suspected to be a causative factor, such as Parkinsons, Alzheimers, spinocerebellar ataxias, and Huntingtons....NIH study shows MRI provides faster, more accurate way to diagnose heart attacks
... attack or an episode of unstable angina. Patients suspected of having a heart attack that is not confirmed by an EKG typically have their blood tested for enzymes or other substances ("markers") that indicate permanent damage to the heart tissue. Because the markers are not evident in the blood until several ...UAF Institute of Arctic Biology researcher featured in Science
...resents a creative force whose existence we barely suspected just a decade ago." Mann is working with Brad Werner on a related project dealing with the self-organization of the Alaskan landscape. Werner is currently on sabbatical and studying at UAF's Geophysical Institute....Molecule helps pupils respond to light
... reflex, albeit diminished, Yau and his colleagues suspected that the melanopsin-dependent reflex might be complemented by the rods and cones, the photoreceptors for the conventional, image-forming visual pathway. Thus, they tested the pupillary reflex in another strain of mouse that have lost the rods and con...Hopkins researchers find genetic cause for multi-system disorder
...een in oculodentodigital dysplasia, the scientists suspected its involvement in the disorder. They determined the sequence of its building blocks in affected and unaffected members of 17 families in the United States, the Netherlands, Norway and Turkey, and in 100 additional people. Only people with the disord...Researchers warn biotech advances could be misused by terrorists
...illness, but former Soviet bioweapons builders are suspected using this technology to develop antibiotic-resistant forms of plague, anthrax, and tularemia. Last year, Australian researchers inadvertently created a lethal form of mousepox by adding a single gene to the virus, and this year scientists in the Uni...Fluid flow technology takes a cue from fast-swimming sharks
... Koeltzsch and his coauthors suspected that the diverging riblets drew water away from a shark's "ears" to prevent the noisy sound of rushing water, which inhibits the sharks hearing. If that were true, the riblets could enabl...New mouse model sheds light on lipoatrophic diabetes
...ut different) phenotypes. Dr. Kahn and colleagues suspected that in IRS single knock-out mice the presence of the remaining three functional IRS genes could possibly compensate for the loss of one IRS gene and thereby obscure its true physiological function. Thus, the researchers generated two different strai...Scientists shed new light on the body's internal clock
...been a matter of scientific debate. Scientists had suspected that a molecule called melanopsin, which is found in the retina, plays an important role. Now researchers at Stanford University and Deltagen Inc. have confirmed that melanopsin does indeed transmit light information from the eye to the part of the b...New UNC emergency room wall chart will help health workers respond to chemical terrorism
...ed critical notification numbers in the event of a suspected case or cases," she said. "Chemical agents listed include nerve agents, cyanides, vesicants/blister agents, pulmonary/choking agents, ricin and T-2 mycotoxins." A copy of the poster will be sent free to every North Carolina hospital because the staff...Search for cholesterol absorption genes narrows to two chromosome regions
...h probability - a billion to one - of carrying the suspected genes. "We are excited because our data analysis shows that cholesterol absorption genes are very likely hiding in chromosome 14," says Ephraim Sehayek, M.D., first author and principal investigator of the study and a clinical scholar at Rockefeller...Hopkins study finds combined PET-CT better at detecting ovarian cancer
... were performed on 28 patients with ovarian cancer suspected to have spread to the abdominal cavity. There wer... PET/CT is being used more often for patients with suspected recurrent ovarian cancer," says Wahl. A second study by Wahl and Fishman being presented at the meet...