Researchers Identify A New Cellular Structure: The "Dumposome"
... out, and enzymesto degrade it (all of which Allis suspects work in tandem with dumposomes), but they did not anticipate finding aseparate structure devoted to DNA degradation. Dumposomes seem to target heterochromatin, a distinct form of highly repetitive DNA that contains few active genes."It's been sa...Two Long-sought Diabetes Gene Found
...ntervention Two interacting genes, both unlikely suspects as a cause of adult-onset diabetes, have now been convicted. Mutations of either gene trigger an early-onset form of this extremely prevalent disease, report research teams based at the University of Chicagos Howard Hughes Medical Institute, the Rock...Bog Beetle, Misidentified For 85 Years, Is 'Discovered' At Cornell
...only "Massachusetts" and "Pennsylvania." Liebherr suspects the Harvard specimens may be older than 1907. This beetle loves bogs. "It lives in habitats that people don't usually get to," Liebherr said. "New York state and the surrounding areas have these things that are unique to our region, and they are wo...New Study Shows Steps Leading To Colon Cancer
...e fiction share many features: a mysterious event, suspects with motives and opportunity and a collection of evidence," Peifer wrote. "The best cases end with a smoking gun, clinching the guilt of a suspect. This issue of Science contains three such smoking guns ... firmly establishing beta-catenin as an acco...Insulin Resistance Is A Risk Factor For Atherosclerosis In Whites And Hispanics
...ericans who have diabetes. Howard said he suspects that one reason many people who are insulinresistant have diabetes is the tremendous amount of extra insulin thatinsulin-resistant people must produce to process the glucose in their blood.After a while, he said, their pancreas simply "wears out" and...Study Shows Hereditary Legacy Of Radiation Exposure
...r spermare less efficient at fertilization. Wiley suspects her fairly simple, yet exquisitely sensitive, cellularassay could be used to predict inherited effects of radiation in futuregenerations of animals. The reproductive toxicology professor is now continuingher studies to look at lower doses of radiatio...Salve From Serpents? UD Studies May Explain Why Viper-Venom Protein Stops Tumor Spread In Mice
...e and make it work likeeristostatin." Although she suspects that eristostatin's ability to stop thespread of tumors in mice may be mediated by an integrin receptor, which cancercells have in common with white blood cells, the exact mechanisms remain amystery--for now. "This question has been eluding us, but I...Needlestick Injuries Common In Female Veterinarians, Study Finds
...er veterinarypractice group. Wilkins said he suspects the rate of women veterinarians accidentallysticking themselves may be almost two times higher than reported. Some of the women in the study were asked to think back over the16 or 17 years theyve been working, he said, adding ...Tiny Worm Reveals Workings Of Suspected Tumor Protein
...t into how adenovirus E1A corrupts cell growth.Shi suspects that if p300 provides the exit through which cells leave thedivision cycle and enter differentiation, E1A might shut this exit, trappingcells in perpetual division. Yet while p300 has been implicated in leukemia,gastric and colorectal tumors, much mo...MSU Scientists Eavesdrop On Bacterial
...d for the destruction ofbiofilms," Davies said. He suspects there also are words to turn on or offspecific feeding mechanisms, to accelerate or slow down growth or to makespecific enzymes that degrade toxic chemicals. Davies zeroed in on two chemicals, called homoserine lactones, in acommon biofilm ma...Fish Farmers Must Learn Zebra Mussel Prevention From A To Z
...ion along with a monitoring program if an operator suspects that a pond may be affected. "It's called a Zebra Mussel Critical Control Point Program, where operators identify the points of their operation that may be susceptible to zebra mussel introduction and put measures in place to avoid infestation," Swan...University Of Chicago Researcher Receives Packard Fellowship
...because bacteriadon't have introns. Long suspects that bacteria once had introns and lost them millions ofyears ago to facilitate faster replication. Bacterial cells can mutate rapidlyto adapt to new environments and can replicate as fast as once every 30 minutes. If they had to copy long stretches...Cell Suicide Prevented By Survival Signals
...eceived from theextracellular environment. Steller suspects that Hid protein is an enforcerof social controls. During development, Hid is expressed at various times inmany different regions where cells make critical decisions between life anddeath. It appears that cells that express Hid are sensitive todeath-...New Insight Into Genetic Cause Of Infant Mortality
...N are higher in normal motor neurons, but Dreyfuss suspects that this may be due to the relatively large size of these cells, which requires the nucleus to "crank out a tremendous flow of mRNA." The description of the molecular machinery underlying the disease constitutes a real ray of hope for SMA clinician...Powerful Anti-AIDS Agent Found In Tears And In Urine Of Pregnant Women
...ow the proteins actually inhibit HIV, Dr.Lee-Huang suspects that lysozyme and ribonuclease act together to inhibit theHIV virus. In this scenario, the lysozyme may be acting to break down the outermembrane of the virus, potentially interfering with its ability to invade immunecells. The ribonucleases may targ...Genetic Research Boosts Understanding Of Iron's Path Through Body, Diseases Of Iron Metabolism
...ases the level of iron taken up from food. Andrews suspects that part ofthis mysterious signal may be a fragment of the transferrin receptor that isclipped off the cell surface. Without the transferrin receptor, the intestine inthe mutant mice may never "know" about the lack of iron in the body's cells. ...Fullerene-Based Materials Clear From Tissue, Go To The Bone
...ble and resistant tometabolism by the body. Wilson suspects that the fullerene cages remain intactthroughout the process and do not release toxic metals in the body. Materials currently used can break down after an hour and some amount oftheir toxic metals can be released into the body. Wilson...Lizards do really learn to recognize people
...m to recognize individuals," says McRobert, but he suspects that Fido"fine-tunes" his response with audio cues...mal Behavior Society in Lewisburg,Pennsylvania. He suspects Fido singles him out because iguanas are not normallyhandled and see handlers as a threat: "It's not......protected by an independent immune system, Dr.Ertl suspects they are not adequately protected by systemic vaccines. Consequently, she and her Wistar research team are designing vaccines thattarget the mucosal immune system. To successfully prevent HIV-1, explains Dr. Ertl, a combination vaccine isneeded to in...USGS scientist awarded prestigious Marine Conservation Fellowship
...tal regions and the open sea," said Estes. He suspects that the distances over which human effects are manifested are much greater at sea than they are on land. Nominations for Pew Fellowships are made through an international network of environmental experts. Review and selecti...