Tag: "swap" at biology news

Engineering New Enzymes

...ent" enzymes. This strategy allows one now to swap specific subdomain linked functions, to preserve conserved functions at the interface, and to generate new properties at non-conserved or hypervariable surfaces near the interface. Such new surface linked properties—most prominently ...

Researchers Discover The Pattern Of Inheritance Of Non-Chromosomal DNA

...s inyeast are present in animals, and that you can swap them out," said Butow."Basic biological processes are well-conserved between yeast and humans.That has been borne out over and over again." Genetic disorders caused by mutations in mtDNA include a variety ofneuromuscular lesions and muscle-tissue dis...

Signs of the ancient mariner: Scientists locate elements implicated in human genetic disorders

Chromosomes swap DNA to create variety in the gene pool, but disord...These cleavage events may stimulate chromosomes to swap DNA, makingthe mariner a potential hotspot for genetic change - as well as genetic error. To examine...

Staph bacteria are prolific gene swappers, researchers show

...ing bacteria encounter a new obstacle, they simply swap DNA with their relatives to acquire the genes needed to overcome it. And they do so quite readily, according to scientists from the National Institute of Allergy and Infectious Diseases (NIAID). The research reveals how Staphylococcus aureus, the c...

Historic U.S.-Peru debt-for-nature swap

...t the U.S. Treasury Department. A debt-for-nature swap relieves a government's foreign debt burden in exc...currency for conservation work. The Peruvian debt swap will generate funds for distribution to local Peruvian conservation groups engaged in a wide variety...

Complex gene-swapping spawns a form of lymphoma

...lymphoma develops when large pieces of chromosomes swap locations. Their observations about how chromosome...mphomas can arise when chromosomes inappropriately swap genetic material. After the genetic material is swapped, various genes are removed from their natura...

Natural selection's fingerprint identified on fruit fly evolution

...s. If the species could reproduce, then they could swap genes back and forth and thus would not be truly separate species. Something would have to prevent the transfer of genes, and in the case of Presgraves' fruit flies, that something was the proclivity for hybrid larvae to die before maturing into adul...

Finished Y-chromosome sequence reveals a genomic 'crystal palace'

...Y chromosome does not have a partner with which to swap genes during cell division in order to replace genes that have suffered deleterious mutations, said Page. "This was the theoretical underpinning for the traditional notion that the Y was a genetic wasteland -- the Rodney Dangerfield of the genome," s...

Rumors of male chromosomes demise greatly exaggerated, study finds

...r. But the Y has no sexual "partner" with which to swap out defective genes. "Genes constantly are being bombarded with little injuries mutations. Mutations can either be beneficial or detrimental, but they are far more often detrimental," said Page. "On the Y, detrimental mutations cannot be discarded."...

EGFR: A molecular lab rat let loose in systems biology

...what's the difference?" Big, it turns out. If you swap domains, you alter the rates of secretions on the surface of the cell, and the cells can't organize into tissues. "We can make cells come together and come apart by swapping domains." By defining the functional domains, Wiley listened in on a previ...

Asian bird flu became highly pathogenic through continued circulation and gene swapping

...ects a pig harboring H3N2, these two viruses might swap genes. The resulting "recombinant" virus might be particularly dangerous to humans, depending on which gene or genes it acquired. The report in Nature also notes other indications that H5N1 could evolve into a worldwide threat to humans: the outbre...

Evolvability could be a driving force in drug resistance

...er-order organisms have a tendency to transpose or swap relatively long sequences of DNA," said Deem. Traditionally, a significant number of evolutionary biologists have discounted the idea that evolvability is subject to natural selection, in part because the idea that evolution acts upon the mechanism t...

Leukemia stem cells identified by Stanford researchers

...ease have a mutation in which chromosomes 9 and 22 swap ends. This trade fuses genes coding for two different proteins into a single unit that makes a cancer-causing protein called BCR-ABL. All blood cells in these people carry the swapped chromosome, but only macrophage/granulocyte progenitor cells becom...

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