Tumor Suppressor Gene Located In Liver Cancer Cells
...ompounds. Because the receptor is involved both in switching on a growth inhibitor and inactivating a growth factor, the researchers hypothesized that losing it might well predispose a cell to cancerous growth. Their past studies showing that the protein was abundantly present in normal liver cells, but nearl...New Study Shows Steps Leading To Colon Cancer
...on and off." In normal embryonic development, by switching genes on and off, the protein tells cells which tissues they should make and directs, for example, development of arms and legs, Peifer said. The process occasionally goes awry, however, when beta-catenin becomes active in places where it should no...Scientists Bridge Gap In Cell Communication
...ues determined that the protein is responsible for switching genes on or off by binding directly to DNA, in effect telling the cell to start or stop a specified task. It closes the loop, said Laughon, whose work was accomplished in fruit flies taking advantage of the well-studied process by which sign...Newly Discovered Human Protein Provides Important Target For Cancer Therapy
... humanaging.) "Cancer cells find a way of switching telomerase activity on, whichgives them a tremendous competitive advantage," Dr. Weinberg says. "They havethe potential for continuous reproduction in the body or in cell culture--theybecome immortalized. We want to learn how cancer cells regenerat...A New Biochemical Link Established Between Stress, Sex And Dominance
...rial" experience a dramatic transformation, switching color within minutes from a camouflaged sandy gray...uently and so did the males' bright colors, switching on or off depending on which male perceived himself to be the victor. Perhaps most important, Fernal...Discovery Of Genetic Pathways May Provide New Ways To Combat Candida Infections
...he immune system. But soon, the fungi fight back, switching to a filamentous form and tearing through the macrophage walls, destroying them. Fortunately, in people with healthy bone marrow, other immune system cells called neutrophils come to the rescue to destroy the filamentous Candida. However in patient...ACS Aids Cornell Vet School Cancer Research
...determining the three-dimensional structure of the switching protein, Cornell researchers hope to explain more about the signaling process and to aid in the identification of new drug targets. The Casey study examines a complex retrovirus called walleye dermal sarcoma virus (WDSV) and the tumors it cau...Mathematics Reveals New Pattern Of Brain Cell Activity
...147;Traditionally people thought of brain cells as switching eitheron or off, but that’s much too simple to account for everything braincells do,” said Terman. “They really have lives of their own.” Terman continued: “A common way to think about neurons is thatone cell fires off a s...High Blood Pressure Caused By Salt Retention May Be Related To Oncogenes Implicated In Cancer
... In turn, steroid hormones like aldosteronework by switching on and off other proteins. Dr. Eaton and his colleagues havefound that one of those other proteins is the oncogene, p21 ras, which has beenimplicated in a variety of cancers. "It was a complete surprise to us that an oncogene implicated in ...Researchers Identify New Component Of Circadian Clock
...nd presumably ofmammals as well--are driven by the switching on and off of genes in a handful ofcells. Per is one gene known to be an integral part of the molecular clock offlies. Researchers have also identified mammalian genes similar to per. When the per gene is switched on, it initiates the synthes...Gene Linked To Glaucoma, Hydrocephalus, And Other Birth Defects
... transcription factor, which means that it acts by switching on other genesin response to signals to the cell. The interaction of different genes indifferent genetic backgrounds may help explain why some members of a family whoinherit mutations are more likely to develop symptoms while others do not." ......ad as an indicator of treatment failure, we may be switching people fromclinically successful regimens prematurely, thus depriving them of treatmentoptions they may need in the future," he added. In addition to Abrams, Nienow's colleagues in the study are TarekElbeik, PhD, UCSF assistant researcher/med...Simple Chemical Switch Steers Migrating Neurons
...n vivo studies will be needed to test whether the switching mechanismdiscovered in the cell culture model is actually being used by thedeveloping organism, added Tessier-Lavigne....School Breakfast Participation Leads To Academic, Psychosocial Improvements
...ssion, anxiety and other problemsymptoms. Overall, switching to a universally free school breakfast programincreased the number of students taking school breakfasts, from 15 percent ofstudents at all three schools before the free program to 27 percent of studentsat all three schools four months after implement...Researchers Identify Key Gene That Controls Emergence Of Salmonella
...entists even fooled the bacteria in onestrain into switching back and forth between these two forms. The finding, says Richard E. Isaacson, a professor of veterinary pathobiology,is the first documentation of aphase-shifting process in salmonella and in any food-borne bacteria that isrelated to its ability to ...Common Prostate Cancer: A Different Process Altogether?
...is the first timeanyone's definitively linked gene switching within a family of genes, withcancer." "Most impor...told us this wasn't the case." Theresearchers say switching could be a fundamental process in cancer, and they'vealready linked it with common forms of breast c...Study Suggests New Approach To Asthma
... asthma, it was usually in the nucleus, presumably switching ongenes. Stat1 enters the nucleus after one of the JAK proteins gives it a phosphategroup. The researchers found phosphorylated Stat1 in epithelial cells brushedfrom the asthmatic subjects. But the protein was not phosphorylated in immunecells retri...Scientists identify brain chemicals involved in 'switching on' cocaine addiction
...caine addiction. The scientists found that switching on the delta-FosB gene increased theproduction of one glutamate receptor subunit designated GluR2. Furthermore, thisincrease occurred specifically in the nucleus accumbens. To determine whether an increase in GluR2 production might increasese......atients, Zoghbidecided to change her career plans, switching from clinical medicine to aresearch position. Shortly after switching to research, she started the long,tedious search for the genetic causes of RTT. "Finding that gene ......steronereceptors during the brain's development by switching on a certain gene. Becausefemales produce levels of testosterone that are insignificant, their brainsproduce far fewer progesterone receptors....