Duke Researchers Show "Editing" Can Fix Faulty Genes In New Approach To Gene Therapy
...splices in a piece of RNA sequence attached to its tail end. To test his idea of repairing faulty genes, Sullenger introduceda defective gene into mouse cells growing in a test tube. Then he engineereda ribozyme to recognize a short stretch of RNA near the genetic defect andsplice in the corrected sequen...Learning From Birds And Bees: Engineers Study Insects For Ideas On Tiny "Micro Air Vehicles"
...use motors and hydraulic actuators to move wingand tail structures that provide directional control, for instance. Because of the weight associated with those devices, however,MicroFlyers must use radically different control techniques. Georgia Tech engineers are developing <AHREF="http://www.gtri.ga...Progress In Prion Research: Three-Dimensional Structure Of Prion Protein Fully Uncovered
...in this part ismobile and attached like a flexible tail to the structure described a year ago,the so-calle...prion proteinthis part is attached like a flexible tail to the structure described a yearago, the so-called C-terminal domain PrP(121-231). This newly decod...Duke Lemurs Are Released In Madagascar
...lease process began with a trimming of theanimals' tail hair into distinctive patterns, so they could be better identifiedas they were tracked through the forest. "Two of the project's conservation agents then led a traditionalceremony in which they explained the lemur release project to the ancestorsand...... between the electrodes. A 12-base single-stranded tail hangs off eachend of the spans. There are two kinds of tails, each complementary to the otheroligonucleotide on the electrode. That enables the spans to straddle thedistance between the electrodes, forming a scaffold for depositing silver. To...New Sickle-Clawed Fossil From Madagascar Links Birds And Dinosaurs
...But unlike most birds, Rahona alsohad a long, bony tail and sported a large, sickle-like killing claw at the endof a thick second toe on the hind foot. This unique toe and claw is identicalto the one carried by a group of fast, predaceous theropod dinosaurs called"maniraptorans." It is these maniraptora......he sizeof a turkey, walked on two legs, had a long tail and neck, and quite unlike mostprimitive birds, had stubby forearms that ended in a single, blunt claw. Howthe animals used these strange appendages is a mystery, but they were clearlyunable to fly. While creatures similar to Shuvuuia deserti, incl...Coastal Development Threatens Rare Atlantic Shorebird
...ast, but their long, fancy black and white wingand tail feathers made them a fashion target. From the 1870s to the early 1900s,they were slaughtered by the hundreds of thousands. Most were shot at close range while they hovered protectively abovetheir nests. Resident fishermen and oystermen got 10...The First Rejection: Eggs Sequester Bits Of Sperm For Later Elimination
Portions of the tail of gigantic fruit fly sperm, which enters the egg ...dermining the idea that the only role of the sperm tail is to propel its genetic cargo to the egg. "It was remarkable that the egg accepted so much spermic...Birds Sing The 'Story Of Their Lives,' Theorize Duke Biologists
...howy plumage of male birds, from themale peacock's tail to the brilliant scarlet of the male cardinal. The...h the most exaggerated male traits,such as a showy tail or an elaborate song, showed their genetic fitness becausethey could survive despite the attention-a...Scientists Unearth Remains Of A Predatory Dinosaur In Madagascar
... Scientists recovered pieces of the animal's tail and a near-completeskull, and although the skull b...ities. Theyfirst discovered pieces of the animal's tail and found its skull several dayslater. "We were initially disappointed when discovery of the...Vaccine Kills Spreading Cancer In Animal Model
...f cancers." Giving the vaccine prior to a tail vein injection of cancer cellsprevented developmen...r tocervical cancer cells. She then showed that a tail vein injection of the cancercells could cause lung tumors in mice in two weeks. Tests showed...USGS And Arizona Game And Fish Begin Partnership To Study Western Yellow-Billed Cuckoo
...out 12 inches long and with a bold black and white tail pattern and ayellow bill, this cuckoo is one of a much larger group of birds calledneotropical migrants, said USGS bird biologist Mark Sogge. These birdswinter in Central and South America, spending the rest of the year in NorthAmerica. Researchers s...New Technology Makes Gene Therapy More Effective
...argeting molecules and injected the molecules into tail veins of rats. Those bits of DNA made their way to the nuclei of genetically damaged liver cells. Through a complicated process, the DNA bits "tricked" the damaged cells into precisely correcting the specific defective nucleotide in the DNA that the ...Natural Childbirth Could Play A Role In Brain Development
...rean rats alsohad a far worse response to repeated tail pinching, a standard test for stressreactions. The results hint that babies born by Caesarean may be more vulnerable toschizophrenia, which is thought to involve an overactive dopamine system and hasa statistical link with birth complications...UNC-CH Ligament-Tendon Structure Discovery May Lead To Better Treatment, Scientists Explain
...eim,Calif. "This work, which we did on rat tail tendons, is exciting because no onehas been able to release fibrils from vertebrate tissue before," Dahners said."We now have pictures of fibrils that we have been able to extract from the rattail tendons. No one has ever seen these structures before......esidesin postsynaptic membranes, its extracellular tail reaching into the cleft thatseparates postsynaptic nerve cells from the presynaptic axon terminal. Interestingly, the extracellular part of Neuroligin 1 binds to another group ofcell adhesion molecules, the b-Neurexins. Both, Neuroligins and b-Neurex...A Fresh Look At Love And War Between The Sexes
...ow weapons,like antlers. Or decorations, like the tail of a peacock. All this takes timeand effort, and it's dangerous. In all kinds of species, at all stages of life,males are more likely to die than females." Once males have invested the effort, however, they stand to reap hugereproductive rewards wi...New Gene May Help Scientists Understand More About How the Body Grows
...ut only had disorganized tissue where the trunkand tail should have been. Scientists conclude that derrière controls theformation of the posterior regions of the embryo--that is, the entire body fromthe neck down. These findings, published in the April issue of the journal Development(available no...A Mother's Love? New UD Theory Explains Why Good Insect Moms Risk Death To Save Their Only Children
...young,thereby avoiding guard duty, and often "turn tail and run" from egg-munchingpredators, says Douglas W. Tallamy, whose latest study is expected to reachjournal subscribers this week. His theory, in print for the first time, may better explain why the vastmajority of insects shun parental responsibili...