Award winning researchers reveal potential new role for Glivec
... that this approach will first benefit patients by tailoring their treatments and avoiding unnecessary therapy and often toxic 'trial and error' probabilistic prescriptions. It will also aid regulatory agencies and pharmaceutical companies by speeding up drug development while helping to implement more rationa...Survival of the fastest: scientists 'selectively breed' winning Formula One cars
...o knock crucial tenths of a second off lap time by tailoring a car's setup to whatever conditions are faced on the track. In a paper to be presented later this month at a conference in Seattle, researchers will report on a new computer model based on genetic algorithms that optimises performance by selectively...Findings of novel nanoproperties in selenium produced by bacteria open new area of exploration
...tute have released findings that could lead to the tailoring of bacterial processes for a host of smaller, faster semiconductors and other electronic devices. Pulickel Ajayan, professor of materials science and engineering at Rensselaer, and geobiologist Ronald Oremland reported that three different kinds of...Natural killer cellers are made, not born
...are in close contact with clinicians interested in tailoring immune cells -- such as natural killers -- in treating human leukemias. The current Journal of Immunology publications also contribute to strategies for dealing with the viral menace known as Epstein-Barr virus, a member of the herpes family of viru...Other highlights in the January 21 issue of JNCI
...gesting that the gene might be a useful marker for tailoring chemotherapy or that it is a potential target to improve sensitivity to chemotherapy. Folate is a form of a B vitamin that is critical for DNA synthesis, DNA repair, and epigenetic regulation. About 35% of the general North American population has a......s to provide a better biological understanding for tailoring medical services and treatments based on one's sex. Under the CSD moniker, a multidisciplinary team of doctors and researchers at Georgetown will conduct collaborative basic and clinical research, publish in scientific journals, and provide spea...Proteins may help identify patients who will respond better to treatments in certain cancers
...Gray Cancer Institute in London. "We hope that by tailoring cancer therapy to the biological behavior of an individual patient's tumor, we will be able to improve the success of radiotherapy and provide increased clinical benefits to the patients," she added. Eight distinct groups of tumors, each with simil...Using plants and microbes to purify polluted industrial wastewater
...ies produce different pollutants, and INDCONWET is tailoring the design of constructed wetlands to specific needs. "The efficiency of a constructed wetland depends on plant species, substrate selection and microbiological associations," says Vrhovsek. Project partners are testing various combinations to see wh...A test for sensitivity of normal tissue to radiation damage?
...veloping predictive assays is to enable individual tailoring of treatments. If normal tissue radiosensitivity could be reliably predicted prior to treatment, the radioresistant patients could be offered a somewhat higher dose. In many cases this would increase the chances of cure substantially. Occasionally...AACR forum to discuss stem cells and cancer research: Public policy issues
...there's another step that excites many scientists: tailoring stem cells for the individual patient to avoid any possibility of tissue rejection. This can be accomplished through somatic cell nuclear transfer or "therapeutic cloning." Here, you take an unfertilized egg, and remove the nucleus. Then, you inject ...Fox Chase Cancer Center researchers make significant discovery about function of p53
..., March 2003 print version), have implications for tailoring chemotherapy, designing new cancer treatments, and understanding how to treat cancer in certain populations. The existence of two variants, or polymorphisms, of p53 isnt new, but weve discovered that the variant type in each cell can influence its ...MITs smart surface switches properties reversibly
...at have different switchable properties as well as tailoring the proof-of-concept system for different applications....MIT sugars research affecting bypass patients, drug industry
... One of the heparinases Sasisekharan developed for tailoring heparin is itself the focus of clinical trials. Currently doctors use a compound called protamine to bind to and inactivate heparin in the body when it is no longer needed at the end of surgery. However, "there are serious limitations to the use of p...UCSD bioengineers use computer model to predict evolution of bacteria
..., Palsson says a more immediate application is for tailoring microbes such as E-coli to make chemicals used in the synthesis of drugs and other products such as detergents. "This is could be a totally new technique for designing commodity microbes," says Palsson. "We could design a strain in the computer by...Clinical services must catch up
...ortant in the care of cancer patients we would be tailoring therapies to individuals according to their genetic make-up," he said. Taking as an example the genes BRCA1 and BRCA2, that are associated with breast cancer, Dr Mackay said that the rate of detection of mutations of these genes is poor in many Eur...New technology may benefit health care, bioterror defense
...tire genetic information opens the possibility for tailoring medical treatments or prevention strategies based on a persons unique genetic makeup. "There are several genetic diseases that can be aggravated by diet or environment," Hardin says. "If you knew early on, from infancy perhaps, that you carried the g...Potential of tailoring drugs to genetic makeup confirmed--but challenges remain
...se of death in the U.S., the potential benefits of tailoring drugs to a patients genetic makeup have been confirmed in a systematic study led by University of California, San Francisco scientists. The quantitative assessment of the promise of this new approach known as pharmacogenomics confirms that many ha...Hopkins researchers develop method to predict response to chemotherapy
...be developed, rather we can begin more effectively tailoring the drugs we are using today," says Esteller. "We want to caution that testing for MGMT gene methylation in brain tumors is not yet widely available," according to Herman. Virco Lab Inc. (Great Britain) has licensed the technology from Hopkins an...Scientists Find Multiple New Uses For Worn-Out Tires
...from waste tires, little work has beenperformed on tailoring the properties of tire-derived activated carbons to helpsolve troublesome air-pollution issues. In a collaborative research program between the U. of I. and the Survey, Rood,engineer Massoud Rostam-Abadi andgraduate student Christopher Lehmann compar...Renowned Breast Cancer Experts Present Latest Findings At UCSF Cancer Center Symposium
...netic information is demonstrated to have value in tailoring treatmentto individual cancer patients, as is expected, researchers suggest that within afew years oncologists will routinely be able to order new laboratory tests --making use of sophisticated biosensors called "microarrays" -- to obtaindetailed rea...