New study may explain how fats damage neurons in Alzheimer's patients
... the telltale amyloid deposits and neurofibrillary tangles indicate the presence of the disease in people with Alzheimer's. "The involvement of cholesterol and ceramide in the neurotoxic actions of beta amyloid, and their strong associations with the way the Alzheimer's progresses, suggests a novel approach ...Altered protein involved in a novel link to Alzheimer's disease
...used by increased Abeta peptides), neurofibrillary tangles caused by hyperphosphorylation of tau, and brain atrophy/loss of neurons. Only low levels of the protein P25 are found in healthy brains. However, in the brains of people with Alzheimer's, the p25 proteins are significantly increased. P25 is ...Early clinical treatment can halt progression of Alzheimer's disease, UCI researchers find
...ques and neurofibrillary tangles. Both plaques and tangles accumulate in specific brain regions critical to l... specifically targeted against the neurofibrillary tangles — will be effective. Such a therapy would help treat more advanced stages of Alzheimer's. In t...