International study findings link acne-like rash to effectiveness of new targeted cancer treatment
...circumstances, but an international study of a new targeted cancer treatment cetuximab has shown that patien... work. Cetuximab, also known as Erbitux, is a new targeted treatment a monoclonal antibody designed to home in selectively on a protein called the epidermal g...Phase II trials of second-generation antisense cancer drug planned following successful early study
...be doing something that we can't always say about targeted therapeutics and we were able to identify a biolo...ng the production of a protein from a specifically targeted gene. As a second-generation antisense drug, OGX-011 is an advance on earlier ones in that the molec...Award winning researchers reveal potential new role for Glivec
...ment where the analysis indicates that the pathway targeted by imatinib is activated." Said Professor Cvitkovi...ct more accurately patients who could benefit from targeted therapeutics. We are confident that this approach will first benefit patients by tailoring their tre...Trial shows which brain cancer patients benefit from temozolomide
...ely it would mean that temozolomide would become a targeted treatment. Dr. Monika Hegi told the EORTC-NCI-AACR...olomide. In other words, temozolomide can become a targeted treatment. It is a first step towards molecular diagnostics. In the future, biopsy material optimall...4 October press briefing to focus on minority recruitment to science and engineering programs
...nker mentality now prevails, despite the fact that targeted recruitment is still perfectly legal," said report co-author Shirley M. Malcom, director of Education & Human Resources at AAAS. Emerging from a recent invitation-only think-tank sponsored by the Alfred P. Sloan Foundation, Standing Our Ground prov...UCI scientists successfully target key HIV protein; breakthrough may lead to new drug therapies
...ainst HIV, UC Irvine researchers have successfully targeted an HIV protein that has eluded existing therapies. Researchers targeted Nef, a protein responsible for accelerating the development of acquired immunodeficiency syndrome, o...Researchers ID chlorophyll-regulating gene
...he University of California. The researchers targeted the PIF1 gene because it binds to phytochrome, a protein that is triggered by light and that controls a plant's growth and development. The researchers disabled the PIF1 gene in the species Arabidopsis thaliana, a mustard plant, and compared the muta...16th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics
...laboratory and means temozolomide can now become a targeted treatment. * Dr Ardeshir Ghavamzadeh: Trial results indicate arsenic should now be considered first-line treatment for one type of leukaemia *Dr Kim Chi: Successful results of Phase I trial of the first second generation antisense cancer drug - phase......wo. When mitochondrial fusion goes awry, cells are targeted for programmed cell death, or apoptosis. Apoptosis is a normal process in healthy individuals, but if mitochondrial fusion doesn't work, the wrong cells die, causing disease. This is what happens in two neurodegenerative diseases: dominant optic atr...Targeted therapy knocks out pediatric brain cancer in mice
.... The finding is encouraging in that such precise, targeted therapies may someday replace traditional treatmen...ies with HhAntag offer the hope that such precise, targeted molecular interventions could spare children from the devastating effects of surgery, toxic chemothe...Chemical genetics identifies SARS inhibitors
...were potent inhibitors of the virus; of these, two targeted the virus protease specifically, seven targeted the helicase, and 18 targeted a protein required for virus entry into cells. The successful identifi...Gene expression in liver tumors and patient prognosis
...dings may open the door to the development of more targeted therapies for liver cancer patients. While gene technology has previously been applied to some specific aspects of liver cancer, researchers led by Dr. Snorri Thorgeirsson of the NIH's National Cancer Institute, sought to uncover molecular prog...DuPont developing new protective suits for military, first responders
... to chemical and biological agents. The suits are targeted for use by U.S. soldiers, firefighters, and other first responders. Early feedback from wearers has been positive. The U.S. government has awarded nearly $2.5 million to DuPont and its partners to assist in the development of this new technology....Columbia research to examine gene influence on severity of peridontal disease, therapy response
...l allow the development of pharmacologic therapies targeted specifically to a person's own genetic predisposit...ce the risk of periodontitis and develop new, more targeted therapies." The patient's individual immuno-inflammatory response to the bacterial challenge is beli...Proteins show promise for mosquito control
...e entomology department are working on a new, more targeted approach to mosquito control: inhibiting their ability to metabolize cholesterol. Cholesterol, the sticky substance that accumulates on the lining of human arteries, is an important component of cell membranes in vertebrates and invertebrates. In m...PNNL lands $10.3 million NIH biodefense contract to unlock proteomes of salmonella and pox
...st proteins identified at PNNL as candidates to be targeted by drugs....The search for a kinder, gentler chemotherapy
...ould still absorb the nanoparticles. By applying a targeted heat source - like ultrasound - only to the tumor, doctors should be able to avoid killing healthy cells that happen to take in the nanoparticles. "The possibility for using these nanoparticles as vehicles to target and kill only cancer cells is part...Final Alert: 16th EORTC NCI AACR Symposium
...emozolomide genetic predictive test clears way to targeted treatment New study indicates arsenic could be su...cne-type side effect predicts effectiveness of new targeted treatment Laboratory tests show gossypol abandoned as a contraceptive can sensitise prostate can......ymes, called caspases, wreak lethal havoc in cells targeted for apoptosis. Smac's action is why it was named the "second mitochondria-derived activator of caspases." Specifically, Wang and his colleagues sought to make a small molecule to mimic the function of the Smac protein, since a smaller molecule is be...Chernobyl study: Risk of thyroid cancer rises with radiation dose
...be important in designing and maintaining programs targeted toward the victims of the disaster." While about 30 people were killed immediately from the blast, which remains the worst accident of its kind in history, an estimated 5 million people were exposed to the resulting radiation. "Prior to Chernobyl, t...