Tag: "targeted" at biology news

Scientists call for better protection for coral reefs

...on of the world's reef resources." The papers are targeted to a wider audience, including advocacygroups that can benefit from a synthesis of available scientific andtechnical information on local challenges in coral reef use andprotection. Each will present the consensus expertise of some 2000 ISRSmembers ...

Targeted therapy for lung cancer patients shows promise in extending lives

...ts with advanced stage lung cancer: individualized targeted therapy--easier than chemotherapy, more specialize...the first efforts involving the combination of two targeted therapies in the treatment of advanced lung cancer without chemotherapy. Molecular profiles on each ...

Flies may taste bitter better, first map of insect 'tongue' reveals

...ponse or trigger an avoidance response might offer targeted repellants for human and agricultural uses, he added. Collaborators on the research include Natasha Thorne, Caroline Chromey and Steve Bray, all of Duke....

Salmonella infects cells and saves itself by altering host membrane lipids

...phages. Once inside a macrophage, the bacteria are targeted for death by a mechanism that transports them within a vesicle to a specialized compartment, the lysozome, designed to degrade foreign or unwanted materials. Once the bacterium is engulfed, it takes only about 30 minutes to reach a lysozome. T...

JCI table of contents, 15 June 2004

...lopment of new anti-tumor strategies. TITLE: Novel targeted deregulation of c-Myc cooperates with Bcl-XL to cause plasma cell neoplasms in mice AUTHOR CONTACT: Siegfriend Janz National Cancer Institute, Bethesda, Maryland, USA. Phone: (301) 496-2202; Fax: (301) 402-1031; E-mail: sj4s@nih.gov View the PDF of...

Whole body imaging allows better understanding of the immune system

... for patients, including a widely used molecularly targeted therapy for chronic myeloid leukemia (CML). But now, combining his experience as a cancer biologist and immunologist with that of a broadly interdisciplinary group of colleagues (chemists, engineers, physicists, mathematicians, nuclear medic...

JGI, VBI help unravel sudden oak death & soybean disease

...e identification of cellular processes that can be targeted for novel detection systems and for safe and effective means of chemical or biological control." "The genome sequences for these two Phytophthora [pronounced Fy-TOFF-thor-uh] species provide a framework for understanding how these plant p...

Common worm provides insights into salmonella virulence

...own," he said. "But with the identification of the targeted pathways in the host, we should be able to figure out how virulence factors influence the innate immune response." Aballay said that the C elegans system could be an effective living model for testing or screening new compounds or drugs for treating ...

Researchers identify two potential protein targets for new drug therapies for pancreatic cancer

...our study shows the feasibility of developing such targeted therapy for patients with pancreatic cancer."...

Novel therapeutic bortezomib moves to phase II trial in lung cancer patients

...e-drug combination including the novel molecularly targeted agent bortezomib, the first drug in its class, proved well-tolerated and showed promising efficacy in patients with advanced non-small cell lung cancer, according to phase I trial results reported Saturday at the annual meeting of the American Societ...

When combining new oral anti-cancer agents with standard chemotherapy, timing may be crucial

... to combining the new-generation oral, molecularly targeted anti-cancer agents with standard chemotherapy drug...linical Oncologists. "Many of the new molecularly targeted anti-cancer agents work by inhibiting cancer cell division and growth -- but in doing so, the new ag...

Avastin-Tarceva combo provides 'one-two' punch against lung cancer

...lts of the first clinical trial to combine two new targeted cancer drugs suggest that the combination may prov..., both delivered orally, are among newer so-called targeted cancer agents that focus on specific molecular features of cancer cells. Because they potentially ta...

Margaret Foti to be honored for significant contributions to cancer care

...a of translational cancer research and synergistic targeted therapies," she added. A native of Philadelphia, Foti has dedicated virtually her entire professional career to the AACR, first as an editorial assistant for the association's flagship journal, Cancer Research which she continues to serve as managi...

Why lung cancer in women is different from men

...se." Albain is calling for more research funding targeted to examining why lung cancer is so deadly and why it affects men and women so differently. "Cigarette smoke damages women's lungs more than men's lungs and lung cancer treatment affects women differently than men," said Albain, director, Breast Res...

Nanosphere announces genetic detection advance in Nature Biotechnology

...nge color change that detected the presence of the targeted mecA sequence from clinical samples of MRSA. Further, the high detection sensitivity and specificity of the colorimetric assay enabled testing to be performed without using amplification procedures. "Nanosphere's technology addresses a tremendous u...

RNAi delivery system crosses blood-brain barrier to target brain cancer

... with a weekly intravenous dose of Dr. Pardridge's targeted therapeutic, mice with brain tumors survive almost...nimized in the brain cancer cells treated with the targeted liposome packet. Furthermore, activated EGFR induces DNA replication and cell proliferation. A radi...

JCI table of contents, 1 June 2004

...ve now characterized the portions of EMC1 that are targeted by autoantibodies from the serum of lichen sclerosus patients. They find that patient's serum contains antibodies that detect many different portions of ECM1, but were able to identify a portion of this protein (amino acids 359 to 559) that is detec...

The skinny on diagnosing skin disease

...ve now characterized the portions of EMC1 that are targeted by autoantibodies from the serum of lichen sclerosus patients. They find that patient's serum contains antibodies that detect many different portions of ECM1, but were able to identify a portion of this protein (amino acids 359 to 559) that is detec...

Ecological science for a crowded planet

...of ecological science in decision-making, research targeted at sustainability of a human-dominated Earth, and cultural changes within ecology. "In 2002, the Governing Board asked the committee to develop a plan that would guide both the Ecological Society of America, as well as the science itself in address...

Drug combo effective in advanced breast cancer

...tient bedside found that combining the molecularly targeted therapy Herceptin with a specific chemotherapy com...tion and blocks its effect. It was among the first targeted therapies for cancer when it was approved by the U.S. Food and Drug Administration in 1998. Since th...

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