Tag: "ted" at biology news

International study findings link acne-like rash to effectiveness of new targeted cancer treatment

Geneva, Switzerland: Acne is not a condition that anyone would welcome under normal circumstances, but an international study of a new targeted cancer treatment cetuximab has shown that patients who developed an acne-like rash responded better to the treatment than those who did not....... Professor Eric Van Cutsem told a news briefing today (Thursday 30 September) at the EORTC-NCI-AACR[1] Symp...

Molecular motor implicated in tissue remodeling

St. Louis, Sept. 30, 2004--A well-known enzyme present in the skin and other tissues turns out to be a molecule-sized motor that extracts its fuel from the road it runs on, according to researchers at Washington University School of Medicine in St. Louis. Their discovery appears in the Oct. 1 issue of Science.... ...The enzyme, MMP-1, is a member of a group of enzymes that breaks down collagen, a...

Alzheimer's disease is not accelerated aging

Certain brain changes that are common in normal aging are not the beginnings of Alzheimer's disease. Recent research by cognitive aging experts suggests that changes related to Alzheimer's disease appear in distinct regions of the brain and reflect unique pathology compared with changes that occur in older adults without dementia. ... ..."We're getting a better understanding of the complex const...

Safety of isoflavones in dietary supplements targeted by Illinois initiative

CHAMPAIGN, Ill. -- A multidisciplinary team of scientists at the University of Illinois at Urbana-Champaign is embarking on a comprehensive five-year study of the effects of soy isoflavones found in dietary supplements on various body tissues.... ...At the heart of the project is the safety of phytoestrogens -- estrogen-like ...compounds in plants that are generally thought to have driven the an...

Targeted therapy knocks out pediatric brain cancer in mice

Scientists have identified what may be the first nontoxic treatment for a subset of medulloblastoma, the most common type of malignant pediatric brain tumor. The finding is encouraging in that such precise, targeted therapies may someday replace traditional treatments that can have overwhelmingly negative side effects for pediatric cancer patients. The research is published in the September issue...

Researchers develop fast track way to discover how cells are regulated

SALT LAKE CITY, Sept. 17, 2004 -- Researchers at Huntsman Cancer Institute (HCI) at the University of Utah and a collaborator at the University of California at Santa Cruz report they have developed a unique computational approach to investigate a regulatory network for gene expression that is implicated in cell growth and development. The study was published today in the journal Science.... ......

Simian virus 40 not associated with non-Hodgkin lymphoma, study shows

Non-Hodgkin lymphoma (NHL) patients are no more likely than healthy people to have been exposed to or infected by simian virus 40 (SV40), a macaque polyomavirus that contaminated poliovirus vaccines in the mid-20th century, according to a new study in the September 15 issue of the SV40 has been suggested as a cause of human cancers, including NHL....... In the United States between 1955 and 196...

IBD (Crohn's, Colitis) 'joins' cancer, inflammatory diseases in associated blood vessel growth

Snowmass, Co. (September 13, 2004) Over at least the last decade it has been recognized that the growth of new blood vessels is critical in the pathogenesis of cancer because it increases blood supply to malignant tissue. Relatively recently, a novel pathogenic role of angiogenesis has been established for such chronic inflammatory diseases as rheumatoid arthritis, psoriasis and atherosclerosis....

Sugar-coated sea urchin eggs could have sweet implications for human fertility

For many years scientists have believed they understood how closely related species that occupy the same regions of the ocean were kept from interbreeding. It turns out they were only seeing part of the picture.... ... New research from the University of Washington's Friday Harbor Laboratories shows that common assumptions about sea urchin reproduction don't hold true for all species of the inver...

Researchers report new gene test for isolated cleft lip and palate

Researchers have developed a new genetic test that can help predict whether parents who have one child with the "isolated" form of cleft lip or palate are likely to have a second child with the same birth defect. Isolated clefts account for 70 percent of all cleft lip and palate cases.... ...The National Institute of Environmental Health Sciences, the National Institute of Dental and Craniofacial...

New dye directly reveals activated proteins in living cells

CHAPEL HILL -- A series of experiments reported on this week in the journal Science shows for the first time that novel biosensor dyes can directly reveal activation of proteins in individual living cells....... The research, led by Dr. Klaus M. Hahn, professor of pharmacology at the University of North Carolina at Chapel Hill's School of Medicine, demonstrated that at least one of the dyes Hahn...

Two Virginia Tech energy-related inventions win R&D 100 awards

Blacksburg, Va. -- Sensors invented by researchers with the Center for Photonics Technology, led by Electrical Engineering Professor Anbo Wang, will make oil wells more productive. Meanwhile, an economical fuel cell material created by faculty and students with the Macromolecules and Interfaces Institute, led by University Distinguished Professor of Chemistry James McGrath, will reduce our depend...

Cell's gatekeeper for ammonia revealed in unprecedented detail

Bacteria thrive on it, red blood cells carry it in high concentration, yet the human brain can't tolerate it. The ability of cells to acquire or dispose of ammonia can be a matter of life and death. In the September 10 issue of , UCSF researchers publish the first atomic-level structure of the channel that controls the passage of ammonia in and out of cells....... -- was determined in greater d...

Novel IBD therapeutic approaches reported from Washington Univ., Barcelona, LSU at APS meeting

Snowmass, Co. (September 9, 2004) Inflammatory Bowel Diseases, comprised of Crohn's Disease and ulcerative colitis, are for the most part incurable and their causes are still unknown. About 1 million Americans suffer from IBD and research around the world on new therapeutic strategies against IBD is being reported at a conference sponsored by the American Physiological Society. ......... ...Below...

Wrapping a memory with an experience, capacity for recollection detected in non-human species

(Boston) -- For millennia, the process of memory and remembering has intrigued scholars and scientists. In 350 B.C., Aristotle, in his seminal treatise on the subject, described it as having two forms: familiarity and recollection. Of these, he considered recollection to be a purely human condition. ... ...That tenet is now being challenged by researchers at Boston University. ...... Neurobio...

Common cold virus can cause polio in mice when injected into muscles

DURHAM, N.C. -- Virologists at Duke University Medical Center have discovered that, under the right conditions, a common cold virus closely related to poliovirus can cause polio in mice. ......The researchers injected a cold virus called Coxsackievirus A21 into mice that were engineered to be susceptible to this particular virus. However, instead of developing a cold, the mice unexpectedly displa...

'Defensive' action by influenza viruses demonstrated by Hebrew university researcher

Combating viruses is often a frustrating business. Find a way to destroy them --- and before you know it, they've found a way to defend themselves and neutralize the anti-viral treatment. ......How, exactly, do the viruses do it? In an article published as the cover story in a recent issue of the journal Proteins, a Hebrew University of Jerusalem researcher, Prof. Isaiah (Shy) T. Arkin, has reve...

Single isolated mouse skin cell can generate into variety of epidermal tissues

Researchers at the Howard Hughes Medical Institute at The Rockefeller University have isolated stem cells from the skin of a mouse, and showed, for the first time, that an individual stem cell can renew itself in the laboratory and then be used in grafts to produce skin, hair and oil glands. ... ...The study, published in the September 3 issue of the journal Cell, not only demonstrates for the fi...

Battle between bubbles might have started evolution

Howard Hughes Medical Institute researchers are proposing that the first battle for survival-of-the-fittest might have played out as a simple physical duel between fatty bubbles stuffed with genetic material. The scientists suggest that genetic material that replicated quickly may have been all the bubbles needed to edge out their competitors and begin evolving into more sophisticated cells. ......

Diabodies act as guided missiles targeted to mammary tumor growth

A mini-antibody bearing a payload of tumor-busting radiation thwarts the growth of human breast cancer in laboratory animals, according to research published in the September 1 issue of the journal Cancer Research. ... ...The research shows that a diabody, an antibody surrogate just one third the size of native antibodies, can be used effectively as a targeting vehicle for radioimmunotherapy, sai...

Pig-human transplantation not PERVerted

Organ or tissue transplantation is a potentially life-saving measure for millions of individuals who have suffered organ failure or require tissue grafts for a variety of reasons. Today thousands die while waiting for suitable organs or tissues to become available. One potential means for relieving this shortage has been through xenotransplantation, that is to use organs or tissues from other o...

Patented process preserves transplant tissues/organs

Body tissues such as blood vessels, cartilage and skineven whole organs such as kidneys, livers and heartscould become more widely available for transplants as a result of a patent issued recently to Organ Recovery Systems of Chicago for a method to chill body tissues and organs well below freezing without forming ice crystals. The new process for tissue "vitrification"-chilling tissue and organs...

Advances in tumor angiogenesis Dendritic cells co-opted to the dark side

(Philadelphia, PA) Researchers at the University of Pennsylvania School of Medicine discovered that in ovarian cancer immune cells can change into blood-vessel cells, and eventually promote the life-sustaining vasculature of the tumor. These findings were initially observed in a mouse model of ovarian cancer that the investigators generated and then confirmed in human ovarian cancer. This work m...

Tiny collars fitted on youngest-ever tiger cubs

NEW YORK, NY (August 26, 2004)- Scientists from the Wildlife Conservation Society (WCS) and their Russian colleagues from the Sikhote-Alin Reserve have fitted three wild Siberian tiger cubs under six months old with tiny radio-collars, marking the youngest wild tigers to be tracked by scientists. The collars-made with an elastic designed to expand and eventually break and fall off of the growing...

New genetic research demonstrates possible cause of inherited form of Parkinson's disease

Columbia University Medical Center and Albert Einstein College of Medicine researchers have identified a possible cause of an inherited form of Parkinson's disease, which may be related to more common forms of the disease. The findings are reported in the August 27, 2004 issue of Science.... ...While the cause of most cases of Parkinson's disease is unknown, a few cases are inherited and can be...

Unicellular organisms contribute more nitrogen to ocean that reported earlier

Large, nutrient-poor expanses of the open ocean are getting a substantial nitrogen influx from an abundant group of unicellular organisms that "fix," or chemically alter, nitrogen into a form usable for biological productivity. ... First identified about five years ago, these organisms about 7 microns in diameter are fixing nitrogen at rates up to three times higher than previously reported for...

Sensors at Watts Bar being evaluated by ORNL

OAK RIDGE, Tenn., Aug. 24, 2004 -- Hundreds of barges, tow boats and recreational craft passing through Watts Bar on the Tennessee River will be monitored for nuclear material as part of an effort to thwart terrorists....... The project, scheduled to start in September, is a collaboration among the Department of Energy's Oak Ridge National Laboratory, the Tennessee Valley Authority and the U.S....

Women who have donated eggs sought for national study

Over the last two decades, thousands of American women have donated eggs to help themselves or other women bear children. But little is known about what motivated these women to become egg donors and what, if any, physical and psychological effects resulted from their experience. ... To answer these and other questions, University of Washington researchers have begun a national study and are look...

Length of sex act in flies dictated by genetics

CORVALLIS New research on fruit flies has revealed that genes which are part of the animal's "biological clock" and control a variety of daily rhythmic behaviors also have other distinct and powerful effects which have nothing to do with light, dark or the rhythms of a 24-hour-day. ... The study was just published by scientists from Oregon State University in a professional journal, Current Biol...

Livermore research in accelerator mass spectrometry highlighted at ACS meeting

LIVERMORE, Calif. -- DNA damage formed during carcinogenesis is just one of the topics researchers from the Lawrence Livermore National Laboratory will discuss during the 228th National Meeting of the American Chemical Society in Philadelphia....... Paul Henderson of Livermore's Biology and Biotechnology Research Program (BBRP) will host a mini symposium titled "Emerging Applications of Accelerat...

Imported fitness

...Powdery mildew is a typical fungal infection in crop plants and only the regular application of fungicides prevent huge yield losses in agriculture. Some crops, however, hold a natural resistance against powdery mildew like cultivars of the European barley with a mutation in the Mlo gene. Scientists from the Max Planck Institute for Plant Breeding Research (MPIZ) in Cologne have collaborated...

Illustrated guidebook published for Chinese biomedical scientists and students

Of the half million students from foreign countries studying in the United States, the largest proportion originate from mainland China, Hong Kong, and Taiwan. China is among the top six countries of origin of foreign-born scientists and engineers employed in the U.S. Like many similar institutions, Cold Spring Harbor Laboratory, the world-renowned center for cancer and genetics research in Long...

Researchers report new gene test for isolated cleft lip and palate

Researchers report they now can predict whether some parents are more likely than others to have a second child with the "isolated" form of cleft lip and palate, one of the world's most common birth defects, according to results of a study published this week in the . The research was supported in part by the National Institute of Dental and Craniofacial Research and the National Institute of E...

Embryonic stem cell therapy shows steady benefits in rebuilding infarcted heart

BETHESDA, MD (August 18, 2004) - Despite improvements in earlier diagnosis and treatment, cardiovascular disease is far and away the leading cause of death in the U.S. and the world. ...... According to the latest posted statistics, heart disease causes 700,000 deaths in the U.S. each year, with the number of adults diagnosed with heart disease exceeding 23 million, or 11.5% of the adult populati...

Institute for OneWorld Health nominated for the 2004 World Technology Awards

San Francisco, Calif. Aug. 16, 2004 The Institute for OneWorld Health, the first nonprofit pharmaceutical company in the U.S., announced today that it has been nominated for this year's World Technology Awards in the category of Health & Medicine. The award is sponsored by the World Technology Network (WTN) and held in association with Nasdaq, Microsoft, TIME magazine, magazine, and CNN. ......

Travelers' diarrhea not improved by restricted diet

Travelers suffering from "Montezuma's revenge" may not necessarily have to avoid tasty cuisine. In a comparison of two groups of patients receiving antibiotics to treat travelers' diarrhea, those who restricted their diet to broth and bland foods did not recover any faster than those who ate anything they wanted, according to an article in the August 1 issue of Clinical Infectious Diseases, now a...

Related productivity tools complement computed tomography in lung cancer detection

Palo Alto, Calif. August 3, 2004 The diagnostic imaging modality of computed tomography (CT) scan is very helpful in lung cancer assessment as it spots even small lung tumors that might go undetected in conventional chest X-ray and other tests. ... ...However in general, CT scans could generate as many as 600 images in a single seating most of which might appear repetitive and can lead to inf...

Activated signaling pathway may predict lung cancer patients' response to gefitinib

There are multiple signaling pathways in a cell that control its behavior, such as the ability to survive and divide rapidly. A new study in the August 4 issue of the has found that, among patients with nonsmall-cell lung cancer (NSCLC) whose tumor cells contain a specific activated signaling pathway, the cancer drug gefitinib (Iressa) was associated with a better response rate, disease control...

Dr. Brenda Milner promoted to Companion of the Order of Canada

On July 29, 2004, Her Excellency the Right Honourable Adrienne Clarkson, Governor General of Canada, announced 79 new appointments to the Order of Canada. Dr. Brenda Milner was promoted to a Companion, the highest honour within the Order and one of only two Companions named in this announcement. There can only be 165 living Companions at any given time.... ...Dr. Milner is the Dorothy J. Killa...

Gene defects found in age-related macular degeneration

Howard Hughes Medical Institute (HHMI) researchers have identified subtle defects in a single gene that underlie a hereditary form of age-related macular degeneration, the leading cause of irreversible vision loss in the developed world.... ...Although the genetic mutations discovered by the researchers affect only about two percent of patients with the disorder, the findings offer important insi...
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