Dangerous Chemical Combination Presents Possible Scenario For Gulf War Illnesses
..., the chemicals caused neurologicaldeficits in the test animals similar to those reported by some Gulf War... inDallas. Chickens were selected over rodents as test animals because their susceptibilityto neurotoxic chemicals more closely resembles that of humans, t......a by providing the first realistic animal model to test newtreatments. Researchers have known for many years that schizophrenics behave as if theyhave too much dopamine in the brain's limbic system, which controls emotionand behavior. Conversely, not enough dopamine contributes to clinical depression.Alt...New Cancer Switch Discovered By Duke Medical Center Pharmacologists
...se the cancerous growth of human leukemia cells in test tubes. "These results suggest that inhibition of GRB-2 interactions may provide a useful therapeutic target for treatment of [chronic myelogenous leukemia] as well as other tyrosine kinase-associated human cancers such as breast, ovarian, glioma, squ...Key to Triplet Repeat Brain Diseases Open Door For New Way To Understand, Treat Genetic Diseases"
...more tightly to the enlarged disease protein. To test that theory, the Duke team made artificial strings of glutamines,either 20 glutamines, found in normal proteins, or 60 glutamines, foundin the mutant proteins. They then mixed these glutamine strings with brainproteins to see what proteins bound. The...Tumor Suppressor Gene Located In Liver Cancer Cells
...could help researchers develop an early diagnostic test for liver cancer as well as new treatments, the researchers said. The disease is often far advanced at detection, and the five-year survival rate in the United States is only 4 percent. A report on this tumor suppressor gene appears in the December...Second Breast Cancer Gene Located
...ner and other physicians at Duke have been using a test forthat gene in an experimental program to evaluate how best to counsel at-riskwomen. Because having a mutated copy of either BRCA1 or BRCA2 could make it difficultto obtain insurance or employment, it is important to couple testing withcoun...Computer Program For Quicker, More Detailed Mapping
... generally available computer programs have had to test everypossible combination of locations for each set of these DNA signposts tofigure out which one was correct. This method takes a large computer a relativelyshort amount of time if processing only 15 or 20 markers. However, eachof the human chromoso...Duke Researchers Discover Candidate Susceptibility Gene For Autoimmune Disease
...ein called tumor necrosis factor alpha (TNFa). To test their idea, the researchers injected the TTP-deficient animalswith an antibody that neutralizes TNFa. In a dramatic and almost completereversal, all signs of disease completely disappeared. The findings support preliminary results of human clinical...Duke Researchers Show "Editing" Can Fix Faulty Genes In New Approach To Gene Therapy
...iece of RNA sequence attached to its tail end. To test his idea of repairing faulty genes, Sullenger intr...uceda defective gene into mouse cells growing in a test tube. Then he engineereda ribozyme to recognize a short stretch of RNA near the genetic defect andsp......the field and subjected to mass spectrometry, they test positive for Spanish fly. "We don't think they get it from French chemists," Eisner said....DNA Techniques Allow Scientists To Become Pollution Detectives.
... bodies. "E. coli is a very convenient organism to test for," Tamplinsaid. "We use E. coli to measure the ...n these tests on it for them. We thinkthis type of test could be used all over the country to detectpollution in water." Despite hours of complex testimony ...Humble Pocket Gophers Shed Light On The Genetic Fortitude Of Cheetahs
...ion, whereas the Carmel Valley gophers did not. To test whether the immune systems of the Humboldt gophers functioned at all, the researchers grafted skin from the Carmel Valley gophers onto a few of the Humboldt gophers; the animals rejected them. Soule notes that the range of genetic variation among dif...Bee Sting Treatment Should Emphasize Speed, Not Method Of Removal
...oughcompression as would occur with pinching. To test the premise, Visscher and his UCR colleague, research entomologistRick Vetter, made bees sting them on their own forearms, and measured thesize of the resulting welts after scraping and pinching the stings out atvarious time intervals. Visscher and S...Virginia Tech Researchers Receive Patent For Rapid Virus Detection Technology
... water, recreational waters,and groundwater. The test can be used at water treatmentplants and in proces...er testsfor harmful viruses, Falkinham says. The test detects the presence orabsence of a virus indicator (coliphages). "The rapid virusdetection technolo...Hawaiian Whales Show 'No Overt Response' To Sounds Of ATOC Simulation
...ne-hundredth the power of the ATOC sound source to test effects of sound on nearby whales in relatively shallow water. Whereas the simulation sound source was located 1 kilometer offshore and 40 meters below the surface, the actual Kauai ATOC speaker will broadcast from 829 meters below the surfac...Genetic Alterations Linked To Cancer In Some Blood Samples
...urgery, and oncology. Sidransky cautions that the test does not appear useful as a screening test for cancer. "But it might be helpful in patient management for identifying patients with a very poo...Study Shows Songbirds Switch From Bugs To Berries To Fuel Fall Migration
...experiments with five species of migratingbirds to test the hypothesis that the diet shift to fruit aided birds' abilityto gain mass. These experiments demonstrated that a mixed diet of fruit andinsects led to a significantly greater weight gain for birds than did astrictly fruit or insect diet alone. For...Human-Like Ability, Categorical Perception, Found In Insects
...iology and behavior who gave crickets a perception test originally developed for human infants. "Crickets...or different?" So the neurobiologists turned to a test suggested by Cornell Professor of Psychology Elizabeth Spelke for another category of notoriously un...PET Project Helps Reduce Pollution Threat From Heavy Metals
...resent. Those same stormwater samples were used to test the lab-scale PET system, so the researchers expect the field-scale modelwill work effectively and inexpensively. "Our laboratory work has shown great promise for what weintend to do in the field with this prototype PET installation.We think the syst...Gene Discovery Could Overcome Aluminum Barrier To Higher Wheat Yields Worldwide
...ations includes: USDA scientists developed a new test that will help plant breeders around the world find rice plants that have genes for greater resistance to zinc deficiency. Sulfides formed in rice paddies make zinc unavailable, which costs farmers million of dollars in lost yields annually. [Contac...