Stress Lowers Sperm Count By Overwhelming Cells That Make Testosterone
...HSD are known but only 11ßHSD-1 is active in testicular cells.Hardy's data suggest the presence of a third, previously unknown form of theenzyme. "We don't know exactly what this enzyme is, though it is very similar to11ßHSD-1. And we can see what it is doing. This enzyme is the one that maintainste...Reanalysis Of International Data Finds Sharp Decline In Sperm Density
...s, where spermcounts have fallen, the incidence of testicular cancer has increaseddramatically over the last 25 ...land, where sperm counts arestill relatively high, testicular cancer rates have remained low. #......t of the cell--and thereby causing sterility,as in testicular maturation arrest. In the UCSF study, the researchers determined that a gene, known asNDT80, plays a critical role in this pachytene stage of meiosis in yeast. Theyfound that the NDT80 gene encodes the critical protein that acts to stim...Discovery Of Mutation May Lead To Help For Male Fertility Problems
...It also is possible that morc could be involved in testicular cancer. "One theory of human testicular tumors is that germ cells are blocked insperm production," Zinn said. "This blockage during cell dif...Researchers discover location of a testicular cancer gene
...t. The genetic basis for susceptibility to testicular cancer, as well asthe basis for its extraordinary ...he identity of genes controlling susceptibilityfor testicular cancer is not known in either humans or in animals. Similarcancer susceptibility genes have already ...Human genome bears a virus related to HIV-1
...opies appear to be active at a low level in normal testicular and placental tissue. The HERV-K genes show even more activity in certain cancers, especially those involving the testes, "but there doesn't seem to be a harmful effect from the activity of these genes," Cullen said. The consistent presence of HERV-K...Disposable nappies may explain the increase in male infertility
...y increase the temperature of the scrotum - the testicular sac - in boys, the research shows. Temperature is critical to normal testicular development and sperm health. The research team monitored the scrotal temperature of 48 health...Scientists discover gene required for testis development
...ertebrates, and helps elucidate the basis of human testicular degeneration syndrome. The Dmrt1 gene has for m...sis, a disease characterized by severely defective testicular development. Although Dmrt1 maps to the position on chromosome 9 which is deleted in these patients...TDS - a new syndrome hitting men's reproductive health says Danish fertility expert
...ting at Lausanne today (Monday 2 July) that rising testicular cancer incidence, poor semen quality, high frequen...Denmark show that reproductive diseases, including testicular cancer, are still increasing. Nearly 1 in 100 (mostly young) men are now treated for testicular canc...Research: U.S. boys also reaching puberty earlier than in past years
...ssessment of which is less subjective than that of testicular growth. The difference could be greater if the gen...arts puberty, the higher his risk is of developing testicular cancer, just as early-maturing girls are at greater risk of developing breast cancer. Then there are...Worlds largest scientific society convenes regional meeting October 10-13 in Lincoln, Neb.
...d for decades in treating small cell lung cancer, testicular cancer and Kaposis sarcoma. The researcher will present synthesis and properties of new members of the etoposide drug family. (David Berkowitz, University of Nebraska at Lincoln, Department of Chemistry, 402-472-2738) Bakers and other food proce...Exposure to toxin in certain foods could cause testicular cancer
... compound found in certain foods may be a cause of testicular cancer in young men. Writing in the February issu...or even before birth may set up the testes so that testicular growth during puberty triggers the launch of testicular cancer. Ochratoxin A results from molds tha...Gene linked to infertility in mice
...ween the human homologue of piwi, called hiwi, and testicular cancer. (Please visit http://www.dukemednews.org for a news release featuring the Oncogene paper.) There are a number of genes linked to male infertility, but only two, which includes miwi and crem, have been directly linked to sperm produ...New cell line increases research opportunities
...here who are working on male infertility problems, testicular cancer, and possibly for germ cell gene therapy. Germ cell gene therapy is a form of gene therapy that involves altering the genetic makeup of eggs or sperm, permanently changing the genome of an individual's offspringas opposed to standard gene ther......didymal semen it was 73 boys for 100 girls and for testicular semen it was 91 boys for 100 girls respective ratios of 1.19, 0.99, 0.73 and 0.91. When divided into single and multiple births the respective ratios were: single births: 1.10, 0.98, 0.83 and 0.71multiple births: 1.14, 1.00, 0.65 and 0.90 The resear...Mice become first animals to produce other species' sperm
PHILADELPHIA -- With pinhead-sized grafts of testicular tissue from newborn mammals, scientists at the Uni...e scientists a valuable model to better understand testicular function, many aspects of which remain murky. Dobrinski and colleagues grafted as much as one cubic ...Islet cell transplantation for diabetes turns corner
... The mixture of cells consisted of islet cells and testicular Sertoli cells taken from neonatal pigs. Sertoli cells are thought to have a special ability to subdue immune system T cells, which normally fight against the presence of anything foreign. The researchers gave the cells to 12 children with type 1 diab...Sertoli cell transfer restores sperm production in infertile mice
...n be caused either by defective germ cells or by a testicular environment that fails to promote proper spermatogenesis," Brinster said. "While several assisted reproductive technologies, such as in vitro fertilization or intracytoplasmic sperm injection, are now available for patients with low sperm counts, in...Two landmark fertility studies give hope to young male cancer patients
...two world 'firsts' mice born from frozen immature testicular tissue taken from one set of mice and matured in others, and a rabbit born after maturing testicular tissue in a host mouse. In the second study UK researchers have shown that it is feasible to obtain ......nd neck, brain, cervical, prostate, pancreatic and testicular cancers, results in decreased expression of TSP-1 and increased tumor blood vessel formation," says Rhoda M. Alani, M.D., assistant professor of oncology, dermatology, molecular biology and genetics in the Kimmel Cancer Center at Johns Hopkins and di...