Tumor Suppressor Gene Located In Liver Cancer Cells
... it readily accessible for use in both liver tumor therapy and diagnosis. Researchers often work backwards from the biological changes involved in cancer to find the genes responsible for these alterations. In this case, however, the functions of an already-identified gene led Jirtle and his team to hypothe...Duke Researchers Show "Editing" Can Fix Faulty Genes In New Approach To Gene Therapy
...slated into protein. The editing approach to gene therapy ignores the defectivegenes, which are encoded in D...e proof-of-conceptstage, Sullenger's twist on gene therapy addresses many of the problemsthat have complicated early gene therapy efforts....Florida Researchers Discover Gene For Fatal Childhood Disease
...igashi syndrome, and in the long run offer genetic therapy for it." People and mice who have Chediak-Higashi syndrome are much moresusceptible to cancer, which spreads faster and more widely than in typicalcancer patients, Kingsmore added. A better understanding of the gene's role in the spre...Low-Protein Diet May Reverse Kidney Disease
...pkins study shows. The results suggest the dietary therapy should be tried before drug treatment for nephrotic syndrome, a chronic kidney disorder that often leads to kidney failure. Scientists have not solved the paradox of why eating less protein benefits some patients -- sufferers already lose too much pr...Green Glow: Not Only For Halloween
...e therapy, doctors could inject GFP along with the therapy substance, and by checking for fluorescence, determine whether the therapy had been properly delivered. By "tuning" the green dye to different colors, scientists studying vis...Animal Studies Indicate Aging Brain Responsive To Estrogen
...dsto the cognitive decline. "Estrogen replacement therapy might 'shore up' the synaptic connectionsof neurons affected by the disease," said Einstein. Earlier behavioral findings from Williams' lab had already shown that olderfemale rats' spatial memory is improved by estrogens administered in a cyclicfash...Bacterial Protein Structure Hints At Mechanism Of A Class Of Premature Aging Diseases
... understandingmay eventually help to work out gene therapy techniques." Collaborators on the project were Adhar C. Manna, Karnire S. Pai, DirksenE. Bussiere and Christopher Davies....New Nonviral Gene Therapy System Could Help Fight Cancer
...rs at Ohio University haveinvented a nonviral gene therapy system that could aid scientists inthe search for ...ceractivity," Wagner said. The T7 vector gene therapy system is unique because it is anonviral system that works in the cytoplasm of a cell, Wagner said.O...Erodible plastic microspheres could be effective oral drug delivery system
...peuticagents not taken orally today--exist in gene therapy and in the use ofvaccines; in treating AIDS, cance...n the form of plasmid DNA could provide convenient therapy for a number ofgenetic diseases such as cystic fibrosis and hemophilia. Edith Mathiowitz, who led ...Herpes-Based Gene Therapy Is Key To Promising Liver Tumor Vaccine
...accine is oneof the first to be created using gene therapy and to target livercancer. It's also rare for a va...oup turned to Dr.Federoff in an effort to use gene therapy to supplement thebody's immune response. The modified cells created by Drs. Federoff and Fong a...Herpes-Based Gene Therapy Is Key To Promising Liver Tumor Vaccine
...ccine is one of the first to be created using gene therapy and to target liver cancer . It's also rare for a...up turned to Dr. Federoff in an effort to use gene therapy to supplement the body's immune response. The modified cells created by Drs. Federoff and Fong act a...... his team's research is an important first step, a therapy for HCV is not around the corner. The study is published in the April 14 edition of Virology (vol. 230, no. 2, pp. 217-227, Academic Press) and funded by the National Institutes of Health. Co-authors are Drs. Marcus J. Korth, Norina M. Tang, ...Emory Researchers Advance Gene Therapy Studies For Metastatic Melanoma Treatment
...ough the circulatory system." Most clinical gene therapy for melanoma now being conducted around the countr...indeed fast-growing, calling for a more aggressive therapy than might a more gradual growth. For example, Drs. Ansel and Armstrong have recently completed a...Genetic Trickery Offers New Way to Target HIV
...strategy opensup a new research avenue in the gene therapy of AIDS. They havefiled for a patent on the process. To replicate itself, HIV depends on a molecule known as atRNA primer to attach to a strand of HIV's genetic template,providing a foothold so that the enzyme reverse transcriptase can copy the ...Jefferson Scientists Discover Mechanism Of Viral Link To Disease Commonly Associated With Asbestos
...ansmitted. They are also working to develop a gene therapy approach to restore growth-suppressor function of the pRb2/p130 gene. To date, the treatment has shown success in animal studies and is about to enter phase 1 clinical trials in humans. Dr. Giordano was the first to id...Gene Shears In Cutting Edge Anti-Aids Trial
...ene Shears licensees plan to test theribozyme gene therapy against a range of other human diseases. Research is also well-advanced into uses of ribozymes in the agriculturaland food industries. For example, a range of virus-resistant vegetablecrops developed with gene Shears' ribozymes will undergo field t...Researchers To Investigate Years Before Menopause
...mones from birth control pills and replacement therapy are unknown. "Much of what we know about women's reproductive cycles came from the first cohort of the Tremin Trust," says Mansfield, a faculty member in both Colleges of Health and Human Development and the Liberal Arts. "Informatio...Molecular Piracy Turns Protein Into Traitor
...ne antagonists may lead to novel approaches to HIV therapy either to prevent initial infection or to slow down disease progression in an already infected patient. Importantly, this research shows for the first time that it is possible to block both types of chemokine receptor used by HIV with one molecule. "...Gene For Last Major Form Of Batten Disease Discovered
...or LINCL. The finding also opens the door togene therapy and enzyme therapy for the disease. Preliminary studies of enzymetherapy have been partially successful for Gaucher?s ......or manymonths or years, "this gene-based intrakine therapy should have a potent andlong-lasting anti-HIV effect." In contrast to Chen's approach, the best current HIV treatment is withcombinations or "cocktails" of drugs. While these combinations of medicationsshows promise of extending the lives of ...