NASA Research Helps Map Protein Structures -- Key In The Development Of New Disease-Fighting Drugs
...ly improvethe quality of life of people on insulin therapy by reducing the number ofinjections they require. It also would reduce the cost of treatment, whichaccounts for one-seventh of the nation's health care costs. A protein crystal growth study conducted during a recent Space Shuttleflight obtain...UF Discovery Of Chicken Gene Mutation Aids Study Of Rare Inherited Eye Disease
...aid. Rowland now is developing a form of gene therapy for chickens with thedisease. "The eye offers a unique opportunity to employ gene therapy because itis a closed system," she said. "The cells in the eye are highly specializedfor the work th...University of Kentucky Neuroscientist Develops Unique Device For Treatment Of Brain Tumors
...spite aggressive treatment with surgery, radiation therapy andintravenous chemotherapy, Patchell said. Intravenous chemotherapy often causessevere toxicity, so patients cannot be given enough of the drug to haveeffective results. In addition, many anticancer drugs cannot cross theblood-brain barrier in con...Antisense Therapy Prevents Burkitt's Lymphoma In Mice
...archers at Jefferson Medical College have used DNA therapy and thehost immune system to stave off the develop...mith, Ph.D, have used a treatment called antisense therapy to prevent the development ofBurkitt's lymphoma in laboratory mice, showing that this protection is ...Transplanted Skeletal Muscle Mimics Heart Muscle; Helps Failing Heart Pump, Duke Researchers Say
...Mary Reedy, and Kelley Hutcheson, hopes totest the therapy by next year in patients with severe heart failure who areawaiting heart transplants. The research was funded in part by the AmericanHeart Association and a grant from the National Science Foundation EngineeringResearch Center. The researche...Molecular Circuit Breaker Can Prevent Runaway Cell Growth
...itive to themany conventional forms of anti-cancer therapy that act by damaging the DNA oftumor cells.......H. pylori cure rate than other methods. The triple therapy is a combination ofthree drugs: a powerful acid-in...cluding OHSU. Patientsin the study took the triple therapy drugs twice a day for either 10 or 14 days.Among those patients who followed the full course of trea...UNC Scientists Succeed In Inserting Gene In Human Cells Via Artificial Chromosome
... "I want to stress that this work is not a gene therapy cure for anydisease yet, but I do think it is a major technical step forward," Vos said. "Itmoves the field from working with shrunken versions of human genes to entirefunctioning genes. We have shown the genes function and function for a longtime." ......al patient can help determine who needs additional therapy to improve their chance of cure," explained Dr. Howard Scher, chief of the Genitourinary Oncology Service at Memorial Sloan-Kettering and a co-author. BPH Found Not to be a Precursor to Prostate Cancer In a related finding, researchers found that ...Research Team Finds Gene Causing Two Types Of Muscular Dystrophy
.... "We are aboutto embark on safety trials in gene therapy for some of the muscular dystrophies,and finding new genes means more possibilities for intervention using genetherapy." The current discovery caps a process that began 15 years ago when Brown met withmembers of a family affected by an unusual muscl...International Conference Addresses Drug-Resistant TB Epidemic Ravaging Russia
... decades of refusal to adopt the WHOstandard of TB therapy used successfully around the world to contain, treat andcure TB patients. Already, one in 10 of the 1.5 million prisoners in the penalsystem has active TB and at least 12 percent have MDR-TB. In some prisons suchas Colony No. 33 in Mariinsk of the K...Gene Therapy Showing Promise In Fighting Melanoma
... This study is unique, Hogge said,because the gene therapy can produce a broad range of immune responses agai...id this study closely parallels work in human gene therapy to treatcancer, and provides additional information that benefits those projects. "Wetry to target a......ction or thatstimulates TTP production, or as gene therapy to increase TTP production in apatient. The Food and Drug Administration recently approved a Crohn's diseasedrug, infliximab, that neutralizes TNF through another mechanism -- butillustrating, Dr. Blackshear said, the applicability of the res...Gene Therapy Animal Study Offers Hope For Some Neurodegenerative Diseases
...o researchers offers the first evidencethat a gene therapy technique involving ribozymes, molecules that disr...autosomal dominant diseases, saidLaVail. Most gene therapy approaches have focused on diseases that occur when the twocopies of a particular gene fail to produ...Combination Therapy For Brain Tumors Holds Promise For Longer Survival After Surgery
... twodecades. Right now, surgeons rely on radiation therapy after removal of thetumor to mop up microscopic ca...tivate erbBreceptorproteins. One is a form of gene therapy to make cancer cells express anon-active receptor. "The second form of inhibition, which is even mor...Out On A Limb: Young Burro Receives Artificial Leg At Colorado State
...ng process." She gave Lee instructions forphysical therapy on the burro but said, "I don't know how much physical therapycan help, because Primrose is on that leg all the time, and once those musclesget tired, there's little more you can do." The couple will burro-sit Primrose in the near future to f...Hutch Researcher Wins 'Nobel Prize Of Applied Research'
... specifically mammals, reptiles and birds. In gene therapy experiments, researchers typically use viruses as ...as used in 1990 duringthe world's first human gene therapy trial at the National Institutes of Health, it is the first time a retroviral gene expression kit ha...Stroke Risk Increased In Patients With High Oxygen Use In Brain
...isk." But the investigators think surgical therapy may be helpful. They wantto revisit a surgical tec...ed that the EC-IC bypass was nobetter than medical therapy in reducing risk of stroke, but that was before therisk of hemodynamic failure had been clarified. N......week data showed that 88% of patientstaking triple therapy with Agenerase+Epivir+Retrovir achieved viral load...V treatment calls for first line use ofcombination therapy that generally includes a protease inhibitor. Since beingintroduced in late 1995, protease inhibito...Gene Therapy In A Liquid May Lead To Quicker, Easier Methods For Treating Disease
...Medical College have successfully administeredgene therapy orally, effectively curing lactose intolerance in rats. In provingthat gene therapy may potentially be given this way, the work may eventuallylead to treatments for important human dis...