Scientists Identify Retrovirus-Like Components In Corn Genome
... and they indicate that some plants may be able to thwart certain viruses that are devastating to humans. Every living organism has a genome, the DNA in each cell's nucleus, which includes the active genes that determine the organism's characteristics. However, the genome also contains inactive pieces of DN...Study: Hydrogen Bonds Aren't Key To DNA Pairing After All
...l: Nucleoside analogs are already used as drugs to thwart the enzymes that copythe genes of tumor cells and viruses. The work was supported by the National Institutes of Health....Biochemists Gain Crystal-Clear Insight into 'Ancient' Enzyme
..."There are a great many places one could target to thwart this enzyme,"Fierke said....Clever Chemistry Protects Beetle Babies
...scopic body hairs, Epilachna borealis pupae can thwart just about anything that would eatthem, Cornell University researchers report in the July 17 issue of the journal Science . "Industrial chemists have only begun practicing combinatorial chemistry in thelast five years. They generate a very large n...Structure Of Enzyme Involved In Gentamicin Resistance Revealed For First Time
...d presents a possible targetfor designing drugs to thwart resistance. "Our structure of this antibiotic-resistance enzyme reveals how remarkablysimple proteins can present life-threatening problems for critically illpatients," says senior author Stephen K. Burley, M.D., D.Phil., Richard M. andIsabel P. Furl...NASA Using Space Incubator To Understand Breast Cancer
...eir growth, and how we might use that knowledge to thwart malignancies before they are created. The type of mammary cells we are growing comes from an individual susceptible to breast cancer, and that susceptibility is likely driven by damage caused by ionizing radiation. Space exploration will involve slig...Cellular Target Of Leprosy, Deadly Viruses Found
... to prevent nerve damage in leprosypatients and to thwart infection by the deadly viruses, according to tworesearch teams that reported these findings in two articles in the December 11,1998, issue of the journal Science . One team included scientists from theHoward Hughes Medical Institute (HHMI) at the U...UCSF Lab Makes Observation That Could Explain Ability Of Modified Cold Virus To Kill Cancer Cells
...usethese cells would lack the defense mechanism to thwart the viral replicationprocess. The genetically engineered virus would be able to replicatecontinuously, disrupting cell behavior, and ultimately causing cell death. This theory has borne out, first in laboratory cell cultures and now in clinicaltrial...Roundworm studies yield new insight into organ formation
...ction of the mouse enzyme, and possibly newways to thwart the cancer gene. "If the mouse gene works in C. elegans , we can then look forinhibitors of the gene, and if we find them, ask whether these inhibitors affectcancer progression in mouse cells," said Kimble. The scientists also plan to insert the w...Errant nerve cells risk a clockwork death
...sends a signal back to the main nerve cell body to thwart thesuicide program. Experiments are underway to isolate the survival signals....Chromosome centers defined and sequenced for model plant
...ondensed, packed and coiled so tightly that it can thwart many types of anaysis. The techniques that allowed genetic and physical mapping of the centromeres in yeast required researchers to analyze the genetic contents of "tetrads" -- clusters of four reproductive cells that are formed from a single parent ...Researchers glimpse polio virus as it enters host cell
...s gives you a route to potentially making drugs to thwart them," says Hogle. Ironically it was the onset of good hygiene, brought about by improved sanitation systems at the turn of the century, that turned polio from an endemic disease, with a few cases here and there, into a public health disaster. Depri...Scientists discover key molecule in transmission of AIDS virus
...venue to develop therapies or a vaccine that could thwart HIV infection in the body. Dendritic cells are a subset of immune cells that present foreign proteins or antigens to another group of cells called T-lymphocytes, the foot soldiers of the body's immune system and the ones targeted by HIV. Once ...Scientists move in on genes conferring susceptibility, resistance to cancer
...tep would be developing drugs that either mimic or thwart this molecular outcome. Significantly, the process of identifying individual genes in the mouse is becoming increasingly efficient, thanks to progress on sequencing the overall mouse genome. Comparing gene regions that confer susceptibility or res...NHLBI study shows reduced fat intake to lower cholesterol is safe and beneficial for children
...n children with high levels of LDL cholesterol may thwart the development of atherosclerosis without adverse effects." During the past decade, scientists have found increasing evidence that atherosclerosis begins in childhood and that children and adolescents with high cholesterol levels are more likely tha...Hopkins' Young Investigators' Day winners shine in the spotlight
...ve behavior. Her work could help develop drugs to thwart metastasis. These other young scientists have won awards: The Mette Strand Research Award goes to Michael T. Hemann for work focusing on how telomeres the structures that protect the ends of chromosomes can lose their function and how that lo...UF researchers reverse metabolic disorder in mice
...es adherence to an unpleasant protein-free diet to thwart development of mental retardation. Now University of Florida researchers report a small victory on the road to a cure: In male laboratory mice, they have effectively reversed the condition with a single treatment of gene therapy. The findings raise ...Scientists discover how some viruses take strong hold of cells
...e Structural Biology, may lead to improved ways to thwart viral infections, and may help scientists design virus-based vehicles for gene therapy. The study reveals that the receptor protein for coxsackievirus (known as coxsackievirus-adenovirus receptor, or CAR) forms pairs on the surface of human cells, wi...Study: King Midas' feast offered golden opportunity for fungi
...to the chemistry of wood decay may suggest ways to thwart fungal growth at existing historical sites," he says. Currently, Filley and Blanchette are working on microbial decomposition processes in the Canadian Arctic where soft-rot fungi are quite active. As a pilot study, they traveled to the High Arctic t......ed that their host bacterium will not find ways to thwart or resist their lifecycle; the enzymes they employ to get out of the bacteria target essential components of the bacterial cell wall that will be difficult to change. To verify this theory that resistance will be a rare event, the researchers repeat...