Tag: "tissue" at biology news
'Trap' crop saves Texas cross timbers melon production
... postulates meant: Identifying the bacterium in tissue
samples of plants during all stages of infection; Isolating the bacterium by growing it in culture dishes; Reinfecting a healthy plant with the isolated bacterium to see if it would result in infection; and Letting squash bugs feed on infected...
Mitochondria in spinal cords is ALS target according to UCSD medical researchers
... to the motor neurons." In laboratory studies with tissue
from animals and humans, the UCSD team determined ...t SOD1 ignores all other mitochondria in cells and tissue
outside of the spinal cord, and binds only to the mitochondria in the large motor neurons that begin...
Other highlights in the July 7 JNCI
...es of molecular drug effects in tumor or surrogate tissue
or functional imaging studies, were not routinely incorporated into the study design and rarely formed the primary basis for dose selection. The authors conclude that although phase I studies of targeted anticancer agents in general continue to use ...
RICE gets $1.1m from DOD to study neurofibromatosis
...ch causes tumors to grow in various types of nerve tissue
throughout the body. But while the cause of the disease is well-known -- a mutation in the gene known as NF1 -- nagging questions remain about the biochemical processes that govern the illness. Why, for instance, are some patients more severely affec...
Technology could enhance accuracy of breast biopsy
... biopsy at the right spot, they take up to a dozen tissue
samples. "If you're in the wrong spot and you don... to add another dimension of information about the tissue
properties at the needle tip. Light can provide structural information such as cell or nuclear size,...
Croatian skeletons reveal changing status of cancer in Europe across the centuries
...r evidence of neoplasms (uncontrolled and abnormal tissue
growth). The remains in the collection date from 5...ed bone neoplasms (obviously, as bone was the only tissue
remaining): two fibrous cortical defects, an osteochondroma and an osteoma. All three conditions wer...
UCSD team determines cellular stress within body is critical
...ur findings to cancer cell biology," Ho said. "The tissue
microenvironment of tumors is unique because the u...as previously thought that the kidney was the only tissue
in the body that was subject to osmotic stress. The kidney controls how much water and salt is in o...
Chemoradioimmunotherapy for advanced breast cancer: hope for the future?
...gs and radiation therapy. Using metastatic tumour tissue
taken from a patient with advanced breast cancer, Dr. Giannios's team analysed the cells to determine if known oncogenes were being overexpressed. In addition to finding overexpression of the oncogenes bcl-2, HER-2, Raf-1 and cdc25c they also detecte...
Macrophages, not stem cells, correct liver disease by fusion
...ng many scientists that stem cells repair diseased tissue
by transforming into other cell types in a process...ch more targeted toward treatment of damaged liver tissue
than using whole stem cells from which they're derived. The discovery "strongly argues against stem...
Combination of gene therapy and gene silencing prevents neurodegenerative disease
...biophysics, and neurology. "We have had success in tissue
culture, but translating those ideas to animal models of disease has been a barrier. We seem to have broken through that barrier." Davidson and her colleagues used a viral vector (a stripped-down virus) to deliver small fragments of genetic material ...
Therapeutic cloning no longer a dream, says scientist who produced first cloned embryonic stem cell
...d stem cells. These could eventually be used for tissue
repair and transplantation medicine, said Professor Shin-Yong Moon at a media briefing. Professor Moon and his colleagues at Seoul National University, South Korea, took 242 eggs from 16 healthy donors. Using the cloning technique somatic cell nucl...
Early dexamethasone exposure has long-term neurodevelopment, neuroendocrine effects
...ted to the drug's direct effects on catabolism and tissue
accretion. Dexamethasone-treated animals were also found to have decreased gross brain weights. When corrected for variations in somatic weight, brain weights did not differ between groups in males, but were still lower in females. Neurodevelopmen...
Measuring blood sugar with a wave of the arm
...lly unlimited lifetime that could be placed in the tissue
of the skin," says Craig Grimes, Ph.D., a professor of electrical engineering at Penn State University and lead author of the paper. Designed as an inexpensive device to continually monitor the blood glucose levels of people with diabetes, the passiv...
Endometriosis: Could angiostatic therapy be the new treatment of the future?
... disease. Endometriosis is a disease of the lining tissue
of the womb. It can be very painful and can have a serious impact on the lives of women. At present, there is no satisfactory treatment or cure for the condition, which affects between 10-25% of women of reproductive age1. Annemiek Nap, a doctor at...
Hopkins to found first center for comprehensive study of epigenetics
...ive medical examination to go along with blood and tissue
samples," says Feinberg. "There is great scientific value in what they have and what they do." In particular, Feinberg points out that researchers at the IHF invented high-throughput, quantitative phenotyping -- the ability to rapidly assess the biol...
Clemson researcher places hope on pushy photons
... a pattern of multiple cell types, simulating the tissue
environment on a small scale so we can isolate ce... dead cells with scar cells in heart muscle. Scar tissue
makes heart muscle stiff and can lead to a heart attack. If scientists understand this message, the...
Mice with hyperactive Wnt10b gene eat all they want, but have half the body fat of normal mice
...ich is present in artificially high amounts in fat tissue
from the experimental mice. Wnt10b is one of a fam...0b gene activity repressed fat cell development in tissue
cultures. Now, in the first study in living animals, MacDougald and Kenneth A. Longo, Ph.D, a U-M re...
Early predictor of breast cancer aggressiveness
...te Cell Adhesion Molecule (ALCAM) in normal breast tissue
samples from primary breast tumors. To do this they counted the number of mRNA transcripts of the AL...
Scientists discover genetic marker responsible for two-fold increase in risk of rheumatoid arthritis
...yperresponsive, causing increased inflammation and tissue
damage. "This is not an abnormal gene," said Dr. Gregersen. "It is present in a substantial fraction of the normal population, so it's probably there for a good reason. It may, in fact, help defend against infection." When it comes to the ...
Common chemicals morphing into potential toxins in Arctic
... team also found the compounds in polar bear liver tissue
samples. Other studies are examining exposure levels in humans living in the far north. "It does appear to be an issue that's going to affect Arctic food webs and Arctic people who depend on them. We don't know toxicologically how much of these chem...
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