Duke Researchers Discover Central Role Of Nitric Oxide In Hemoglobin Action
...tanding mystery of how blood carries oxygen tobody tissues and extracts waste carbon dioxide while keeping vessels openand blood pressure steady. Scientists say the discovery, detailed in the March 21 issue of the Britishjournal Nature, could quickly pay off in developing the first effectiveblood s...Dangerous Chemical Combination Presents Possible Scenario For Gulf War Illnesses
... death insome chickens. A laboratory analysis of tissues in the central and peripheral nervous systemsshowed that multiple chemical exposure caused enlarged axons and axonaldegeneration, a sign of widespread nervous system damage. Tests also suggested that the severity of clinical signs depends on howact...Duke Researchers Discover Candidate Susceptibility Gene For Autoimmune Disease
...als had characteristic antibodies against theirown tissues that represent an inflammatory autoimmune response. By comparingtheir mice with other animals that had similar clinical signs, the researchershypothesized the animals were producing too much of a potent inflammatoryprotein called tumor necrosis facto...KU Researcher Eyes The Rain Forest Through The Trees
...ses?'" Terwilliger is hoping her research on plant tissues and plant growth in Central America will help developing countries start a reforestation trend and possibly turn the native plant life into a profitable resource. "In the countries where I have worked, such as Panama, Nicaragua and Costa Rica, there ...New Study Shows Steps Leading To Colon Cancer
...ng genes on and off, the protein tells cells which tissues they should make and directs, for example, development of arms and legs, Peifer said. The process occasionally goes awry, however, when beta-catenin becomes active in places where it should not. It then triggers cells to reproduce indefinitely, or ...Erodible plastic microspheres could be effective oral drug delivery system
...adable plastics, which become moreadhesive to body tissues as the plastics degrade in water. The spheres range insize from 0.1 to 5 micrometers. For purposes of comparison, one thousand1-micrometer spheres could fit end-to-end on a pinhead. A novel proprietaryprocess, dubbed PIN for "Phase Inversion Nanoenca...Purdue Study Aims To Boost MRI Capabilities
...onance imaging allows physicians to "see" internal tissues by using magnetic fields to interact with the protons in hydrogen atoms in the patient's body. When the patient enters the imager, the small internal magnetism of the protons partially lines up with the powerful static magnetic field that is always ...Evolution Re-Sculpted Animal Limbs By Genetic Switches Once Thought Too Drastic For Survival
...to grow a leg out of its head--orient theembryonic tissues as to where they lie in the body. In the case of that particular fly mutant, if the homeotic gene calledAntennapedia is turned on in the head segment, "the cells that bud off from thefly's head think, 'oh, we're sitting in the thorax, we're supposed ...Smoking Mice Lead To Emphysema Breakthrough
...proteinases good for? They apparently help remodel tissues during growthand wound healing, but their role in healthy adults is unclear, Shapiro says."Before we give people drugs to block these enzymes, we really need to know whatthe enzymes do," he explains. Other strains of "mighty mice" will undoubtedly be...Plant-Based Therapies Examined For Colon Cancer Prevention
...dapoptosis goes awry. When apoptosis is disabled, tissues that rely on it nolonger have a way to regulate their cell populations and cancer may ensue. In the study, Shiff and fellow researchers will examine the influence ofadministering different amounts of either curcumin, rutin or quercetin on t...Further Proof That An Altered Rb-2/p130 Gene Leads To Lung Cancer
...107 , are ubiquitous throughout the body’s tissues and play vital roles in cell growth control. Th... gene is ubiquitous throughout the body’s tissues and organs, he believes that the work may have applications to similar diagnostic tests for ot...NIDR Supports Total Genome Studies Of Major Oral Pathogens
...nvolves surgical or mechanical removal of diseased tissues ("scalingand planing"), coupled with antibiotic therapy. Despite such extensivetreatment, the condition can still recur. Without treatment, LJP can result intooth loss by the age of 20. The pathology of Aa is poorly understood. It is known that ...First Selenium-Based Orally-Active Antihypertensive May Lead To New Family Of Therapeutic Agents
...archers to studylevels of selenium in various body tissues of the animals to gain anunderstanding of how it is metabolized. Levels of the hydroxylatedselenium compound in brain tissue were significantly lower than in othertissues, confirming the findings of the behavioral studies. The compounds are therape...Purdue Researchers Track Oil Spill's Effects On Sea Otters
...ems, has studied the Alaskan sea otter's blood and tissues for the past two years. In the course of his field investigations, he developed a technique to determine the level in the otter of an enzyme that metabolizes aromatic hydrocarbons -- a biomarker that may indicate the level of exposure to oil. Initial...Biological Clocks No Longer Found Only In The Brain
... hope that understanding the location of the clock tissues and cells, as well as identifying which genes and ...confirm that body clocks run independently in many tissues outside the brain, and are reset by light, implying that cells harbor novel photoreceptors that aren......ressed in the thymus and in other immunological tissues is still disputable. It is however likely that the APECED gene and its product are taking part in a chain of biological events that regulate immune response. The APECED gene is the first gene which is solely responsible for regulati...Genetic "Short Circuit" Leads To Cleft Palate
... a cleft that runs the length of the hard and soft tissues that form the roof of the mouth. The more severe ...the other molecules is altered so much that palate tissues practically stop growing and a cleft forms in the roof of the mouth. The three key components of th...Gene Therapy Enables Transplantation Without Immunosuppressive Drugs
...to foreign antigens such as those presented by the tissues of atransplanted organ. The term costimulatory refers to the fact that two chemical signals arerequired to trigger T cells to attack foreign tissues. A primary signal thatalerts the cell to the presence of a foreign antigen occurs at the sit...Washington University Licenses Its New Antibacterial Technology
...rethe structures that allow them to cling to human tissues and therefore causedisease. Gram-negative bacteria have an outer lipid layer and do not take upGram stains. Most of Hultgren's work has focused on strains of E. coli that infectthe kidney and bladder. But the same principles apply to many ot...Molecular Mechanochemistry: An Emerging Discipline At The Nexus Of Biology And Physics
Cells and tissues have evolved to thrive in an environment continuallysubjected to fluctuating physical constraints. For example, the constantlychanging fluid dynamics of blood flowing past endothelial cells that linearteries and veins has caused these cells to develo...