Tag: "tissues" at biology news

Researchers pave the way to protein therapy in humans

...y," Dowdy says. The liver, lung, and other tissues of the injected mice also turned bluewhen exposed to the enzyme's target. The animals' entire brains also stainedblue within four hours of injection, indicating that a lot of the bacterialenzyme had refolded there by then. Importantly, the PTD didn't...

Stem cells may be powerful gene shuttle

...tle thanviruses for delivering corrective genes to tissues throughout the body, sayresearchers from the Howard Hughes Medical Institute (HHMI) at Children'sHospital in Boston and Harvard Medical School. Stem cells are immature cells that have the unique capacity to give rise topopulations of mature, functio...

Advance may put gene chip technology on scientists' desktops

...ed chips containing DNA from specific organisms or tissues cantake months to make and cost as much as $12,000 each. "Now, the chips are expensive. You use it one time and throw it away," saidRoland Green, a UW-Madison post-doctoral fellow and a lead author of the NatureBiotechnology paper. The new technique,...

Advances in engineering heart tissue reported by MIT scientists, colleagues

...trode array, they applied electricalsignals to the tissues and got them beating. They then studied parameters...ucts conducted electrical impulses half as fast as tissues grown theold-fashioned way (in an animal's body). A second paper, which appeared in the September 1...

Researchers discover hemoglobin's enzymatic nature

...in evolvedthe ability to carry oxygen molecules to tissues and cart away the waste gascarbon dioxide. In recent years, studies from a number of laboratories have identified avariety of roles for hemoglobin. Stamler, for example, has demonstrated thatwhen hemoglobin binds to nitric oxide it causes blood vess...

Jefferson scientists propose mechanism to control the body's red blood cell and platelet production

...ally control blood cellproduction. For our tissues to have the oxygen they crave, we need to have enoughcirculating red blood cells. Athletes, for example, may artificially increasethe number of blood cells using a hormone, erythropoietin, which helps immaturered blood cells mature. But at the same t...

Major grants support immunology, transplant and diabetes research at the University of Chicago

...uade the immune system to accept certainbeneficial tissues yet remain vigilant against harmful invaders. The Networkwill initially focus on the challenges presented by the rejection of foreigntissues such as a transplanted kidney or insulin-producing beta cells and on theautoimmune diseases such as type I di...

Mechanism found that appears to keep body tissues together

...keep cells from ripping apart."Cadherins hold soft tissues together by binding to identical proteins onadjace...larjunctions play an important role in holding our tissues together. The proteinsare also important in facilitating the cell-sorting process during embryonicd...

A safer way of altering genes

...cdisorders by adding therapeutic genes to specific tissues in the hope that theywill be taken up by enough cells to correct the defect. While this ensures that sperm and egg cells do not become contaminatedby the added genes, it isn't very efficient. As a result, many gene therapytrials have had only...

Harvard and Alexion researchers report successful transplantation of immuneprotected neurons in primate model of Parkinson's disease

...n refers to thetransplantation of non-human cells, tissues and/or organs into human patients. This news release contains forward looking statements. Such statements aresubject to certain factors which may cause Alexion's plans to differ or resultsto vary from those expected including unexpected pre-clinical...

Yale and Alexion report advance in spinal cord repair

...n refers to thetransplantation of non-human cells, tissues and/or organs into human patients. This news release contains forward looking statements. Such statements aresubject to certain factors which may cause Alexion's plans to differ or resultsto vary from those expected including unexpected pre-clinical...

Whitaker Foundation funds Washington University biomedical engineering facility

...neering analyzes biological systems such as cells, tissues and organs, as well as the organization of these s...ing new vessels, tissues, bone, and the healing of tissues after trauma such as a heart attack; molecular engineering, which covers the areas of genomics, bioi...

Science and Amersham Pharmacia Biotech award Young Scientist Prize

...east and worms, and to take a closer look at human tissues that have traditionally been difficult to characterize. There is another SAGE conference in the United States scheduled in 2000. Velculescu was born in Romania, and moved to California with his family in 1977. His interest in the sciences is lifelong...

MGH researchers first to identify genetic malfunction in type 1 diabetes

... called T cells learn not to attack the body's own tissues through the action of MHC Class I molecules, which sit on the surface of B cells and macrophages. There the molecules display tiny bits of "self" proteins to the T cells, the immune system's killers, essentially teaching them to ignore the body's ow...

UroGenesys researchers discover new target antigen for prostate cancers

...erate a renewable supply of primary and metastatic tissues thatare otherwise difficult to obtain. UroGenesys utilizes these tissues in its gene discovery andvalidation programs. "Use of these xenografts is critical to the discovery...

Gene found for Papillon-Lefevre syndrome--a disorder affecting skin and gums

...hat the normal gene is active in skin and gingival tissues and also white blood cells of the immune system. "It is possible that the absence of a functioning cathepsin C affects the structural integrity of the protective barriers formed by skin cells and cells lining the gums, and may also cause the immune ...

Study: avoiding vitamins A, E might improve cancer therapy

...srestricted only to the brain tumors, while normal tissues were not affected by depletion ofantioxidants in the mouse diets." In mice getting low levels of vitamins A and E, no negative effects were seen in normal cells, butabout 19 percent of tumor cells showed evidence of apoptosis. In those ingesting nor...

NYU researchers find that genetically engineered corn releases insecticidal toxin into soil

...giensis (Bt). The toxin is present in the plant's tissues and kills the larvae of caterpillars that attack the plant. It was previously believed that the Bt toxin molecule was too large to be released through the plant's root system. Recently it was shown that the toxin is also present in the pollen of Bt...

Gene mutation may no longer protect certain populations from alcoholism

...ehyde to acetate." Acetate is then metabolized by tissues outside of theliver. "Acetaldehyde is a toxic compound," said Ting-Kai Li, Distinguished Professor at the IndianaUniversity School of Medicine and one of the study's authors, "and the body has an aversive reactionto it." This aversion can manifest ...

Mouse embryo hints at how mammalian body forms

... -- a process that gives rise to the three primary tissues from which all organs and cells of the body emerge... blastocyst they develop normally and form all the tissues of the mouse. We want to understand how to bring about that differentiation in cell culture," he say...

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