Synthesized molecules studied as weapon to stop cell division in cancer cells
...s by changing a peptide bond within Cdc25 from the trans shape (a flattened-Z shape) to the cis U-shape and...in a protein. The researchers synthesized cis and trans shaped inhibitors and introduced them into cancer cells. These inhibitors mimic part of the Cdc25 pr...Genetics, genes and intelligence
...terestingly, CTSD is transported by IGF2R from the trans Golgi network to the lysosome. Citation source: Molecular Psychiatry 2003 Volume 8, number 1, pages 14-18. For further information on this work, please contact Anthony (Tony) Payton, Centre for Integrated Genomic Medical Research, Stopford Building, ...Chemists explore the shape of the key that signals cell division in cancer cells
...s by changing a peptide bond within Cdc25 from the trans shape to the cis shape and back. It is a simple ch...ge conformation change. "We don't know whether the trans shape or the cis shape signals Cdc25 to begin mitosis -- which is the active shape," says Etzkorn. ...Trans fatty acid consumption may increase risk for type 2 diabetes
...eriod between 1980 and 1994. Increasing the use of trans fatty acids by as little as 2% significantly incre... influenced the incidence, but high consumption of trans fatty acids increased the risk for the disease. The main sources of trans fatty acids in the womens...Consume less trans fat, more vitamin B6 and B12, studies suggest
... Americans consume by the millions of tons contain trans fat (hydrogenated oils). Most of these foods are ...ists report. So what should people do? Eat less trans fat and more foods rich in magnesium, B6 and B12, says Fred A. Kummerow, professor emeritus of food ...A New Look At Margerine And Health
... margarines are enhanced whenthey are also low in trans fatty acids, substances which raise total bloodcho...olyunsaturated or monounsaturated, with or without trans fatty acids. Thirtyeight men and women with mildly elevated cholesterol took part in the feedingtria...Lights, Camera ... Reaction: Charting The Biological Effects Of Light InBillionths Of A Second
...le initial structuraltransformation -- namely this trans to cis isomerization." "In the dark, the system is cocked and ready for structural changes," explainsMoffat. A single photon provides enough energy to pull the trigger. Although this paper focuses on only the first nanosecond after light exposure,the......of dietconstituents, such as monounsaturated fats, trans fatty acids, fish oils, andvitamins, not only on the lipoprotein profile but on atherosclerosis itself,"Breslow added. "Genes, Vitamins, Homocyst(e)ine and Cardiovascular Diseases" will be thesymposium topic of Malinow, a scientist at the Oregon......eled residue was on the cis ("outside") or trans ("inside") of the membrane....