New 'Twist' In Proteins Offers Possible Route To Improved Antibiotics
... of the bacteria. Specifically, LpxA catalyzes the transfer of the14-carbon fatty acid hydroxymyristate, to the acceptor, UDP-N-acetyl glucosamine,and functions as the first step of lipid A biosynthesis. Lipid A servesas the outermost coat of bacteria like E. coli. Thus, LpxA is "essentialfor bacterial growth...New Discovery About Genes Has Implications For Genetic Therapy
...some of the information carried by the introns and transfer it to the genes at a very specific site. Much more work will be required before the process could be used for any therapeutic purposes, he said. Lambowitz's team, along with researcher Phillip S. Perlman, a biochemist from the Southwestern Medica...Transgenic Rice Plants Resist Insects, Drought And Salt Damage
...ologies. Now that molecular biologists know how to transfer the insect-resistance gene to rice, Wu predicted, it should work against any lepidopteran (or caterpillar type) insect that eats plants in the larval stage -- and that is about 70 percent of the known insect pests worldwide. Among crops damaged by l......cantharidin; they eat the compound, presumably for transfer to their mates at copulation. "We aren't the first to prospect for useful compounds," said CIRCE-founder Eisner, who advocates "chemical prospecting" to explore and inventory undiscovered sources of potentially useful, natural compounds. "Here is ...Chemists Compute Answers To The Origin Of Gout
...he catalysis. One of their conclusions is that the transfer of a hydroxide ion is involved in the catalysis rather than an oxygen atom as previously believed. This detailed analysis should help the development of inhibitors for the illness. The Computational Chemistry Group uses the latest computer tools t...Maternal Lead Exposure Linked To High Numbers Of Cavities
...vepinpointed breast milk as a likely route of lead transfer frommother to offspring, and that reduced saliva flow has beenimplicated as a likely mechanism of decay in lead-inducedcavities. "Lead is not something that most dentists think of when theytalk about the causes of cavities, but they should," say...E. Coli Genome Reported: Milestone Of Modern Biology Emerges From Wisconsin Lab
...n it was used in the discovery of spontaneous gene transfer or bacterial sex. As a result, the strain, known as K-12, was universally adopted for fundamental work in biochemistry, genetics and physiology. In recent years, it has become the workhorse of biotechnology and is used as a living factory to produce ...Computer Model Offers New Insight On Bacterial Photosynthesis
...st the understandingof light absorption and energy transfer in photosynthesis -- the processthat converts solar energy into chemical energy -- and eventually lead tothe development of more efficient and environmentally clean energy sources. In the August issue of the journal Physics Today, University of Illi...Trojan Horse Virus Controls Hiv Infection
...g in thefusion of the cell and viralmembranes, and transfer of virus from the infected to the uninfected cell. Turning around what occurs naturally, the remodeled shell of VSV -- which nowlooks like an uninfected T cell -- tricks HIV-infected cells into fusing with itinstead. This enables VSV, which easily......RRI). "The normal process of pollen formation and transfer is very sensitiveto a range of weather conditions ..."In most crop plants, the male parts of the flower transfer pollento the female parts, prompting the grain to develop," Dr Chaudhurysaid. "But we are aiming to...Colorado State Scientists Tackle Genetic Makeup Of Obscure Bacteria
...e is a possibility thattechniques could be used to transfer genes that make the bacteria susceptible todrugs into the strain of bacteria that is not currently receptive to drugs andtriggers disease. "One of the important aspects of this research is that not much is knownabout what makes this organism ......l be examinedand children's performance on various transfer task (e.g. evaluating anddesigning tests and explaining outcomes of tests) will be assessed. "Together, the lab and classroom findings will form the basis for thedesign of new curriculum units that are grounded in cognitive theory and will b..."Genetic Factors Influencing Cholesterol Response To Diet"
...receptor (LDLR), apoAI-CIII-AIV, cholesteryl ester transfer protein (CETP), andmanganese superoxide dismutase (MnSOD) was tested with genetic markers flankingthese candidate genes using nonparametric sibpair statistical linkage analysis. The results confirmed significant (p<0.01-0.05) linkage of...Dog Blindness Gene May Help Humans
...y cloning the normal gene, inserting a copy into a transfer vector such as a harmless virus and injecting thegene-carrying vector into the back of the eye. The transfer of the normal gene to diseased retinal cells might prevent orreverse the disease. Aguirre, Acland a...UPMC Researchers Report On Gene Therapy Advances
...gonist protein, or IL-1Ra. Seven of the nine gene transfer procedures approved by the FDA for this protocolha...e safety of the procedure and to confirm that gene transfer to humanjoints is possible. The protocol is the result of extensive pre-clinical safetytesting and ...Yale Announces New Biotech Firm
... For more information about Yale's technology transfer initiatives,contact Gardiner at (203) 432-5446....Gene Transfer Process Generates Seedless Summer Days
...tion of etiquette. Yi Li hassuccessfully used gene transfer techniques to produce seedless tomatofruits and is... the productivity of those fruits. Using the gene transfer process, Li is able to bypass MotherNature by inserting a fusion gene into a fruit plant. This inser...Virginia Tech Scientists To Evaluate Risks Associated With Release of Recombinant Organisms
...tocontact pigs in small and large herds as well as transfer of its foreign DNA toother microorganisms." While recombinant organisms are being developed in laboratories aroundthe world, Inzana explains, some questions exist regarding the safety ofreleasing these organisms into the environment. This s...... at once. It can help us identify the best way to transfer a new gene into a particular plant, determine which are the best switches to turn it on, and whether it is working as it should," explains Dr Adrian Elliott, a member of a small team led by Dr. Christopher Grof that aims to understand sucrose meta......lable starches. If it was possible to transfer this characteristic to graminaceous and other species, it would open a wide range of novel applications of starch as a renewable resource. In addition, cold sweetening is a severe problem in the potato processing industry as...