Researchers determine genetic cause of Timothy syndrome
...ling molecules in the body, and perturbing calcium transport can cause a wide range of disorders. Howard Hughes Medical Institute investigator Mark T. Keating and his colleagues reported in the October 1, 2004, issue of the journal Cell, that a pinpoint mutation in the CaV1.2 calcium channel was the sole c...Rice finds 'on-off switch' for buckyball toxicity
...ke into account exposure rates, uptake mechanisms, transport within the body and much more. Most often, cytotoxicity studies are used as indicators of whether more extensive toxicological study is needed. Based on our results we think buckyballs should be studied in more detail, and we're already working to ar...Protein is key to fatal disorder and normal cell function
...a cellular body that packages proteins for use and transport within a cell. Cln3 also appears in complex fat pl...3 protein may be a crucial protein involved in the transport of vital lipids from the Golgi, where they are made, to where they are needed -- for example, at the...Hardy buoys: Texas A&M project predicts oil spill movements
...ns to raise the sunken ship off the sea bottom and transport it to shallower waters, making recovery operations feasible. But the Navy needed Texas A&M's help. "They wanted to borrow two of the buoys to aide retrieval purposes, especially to measure currents, winds and other data," he recalls. "We received pe...DuPont developing new protective suits for military, first responders
... warfare agents. Through the process of selective transport -- the diffusion of water across a selectively permeable membrane -- this membrane allows sweat evaporation and body heat to escape to keep wearers cooler while blocking harmful agents from entering the suit. The new suits for the military are expec...Proteins show promise for mosquito control
...ito cells. Cholesterol is hydrophobic. In order to transport it in a liquid medium, such as blood or cell fluids, organisms must have a way to shield it from the watery environment through which it moves. That shield is typically a carrier protein, such as SCP-2. Lan and her colleagues reasoned that if they ...Cell's gatekeeper for ammonia revealed in unprecedented detail
...red blood cells, Stroud said. The red blood cells transport ammonia from tissues to the kidney, and transport carbon dioxide to the lungs. The gases are excreted from these organs. "Knowing the mode of action o...Complex cells likely arose from combination of bacterial and extreme-microbe genomes
...talized "organelles" that carry out metabolism and transport molecules throughout the cell. Yeast cells are some of the most-primitive eukaryotes, whereas the highly specialized cells of human beings and other mammals are among the most complex. "A major unsolved question in biology has been where eukaryo...Extreme stretch-growth of axons
...wo possible mechanisms to explain this: increasing transport to a very fast rate or making the necessary proteins at the site, proximal to the growing axons. Smith believes that this form of growth commonly occurs in nature. "For example, it can be inferred that axons in a blue whale's spine grow more than thr...Convulsions in worms mimic epileptic seizures
...sociated with the synaptic vesicles, the sacs that transport neurotransmitter molecules, the team was able to v...molecular motor protein called dynein, which helps transport the neurotransmitter vesicles within cells. In further experiments, the researchers found that block...Other highlights in the September 1 JNCI
...xygen-deprived when they lack blood vessels, which transport these molecules. Cells deprived of glucose accumulate unfolded proteins, but such cells survive this stress by turning on a special molecular pathway--the unfolded protein response--that protects cells from the harmful effects of unfolded proteins. R...What actually influences air pollution over the Indian Ocean?
...here. The main maritime NOx sources are long-range transport of continental emissions, lightning and ships. The new data show pronounced, semi-regular plumes of nitrogen oxide pollution extending all the way across the central Indian Ocean, mainly in the middle troposphere, originating from Africa in the west ...Engineering endurance: The future of the Olympics?
...f gene transcripts and enzymes involved in glucose transport and metabolism. In the mutant mice, expression of these glycolysis associated genes and enzymes was significantly lower. The mutants' ATP levels, however, were normal. Without the molecular machinery to engage anaerobic metabolism, their muscles swit...Carnegie Mellon scientists reveal ways of studying, resolving PCB contamination in US rivers
...ite. ENVR 38. Temperature effects on PCB fate and transport in anaerobic near-surface sediment. (embargo 2:40 p.m. ET, Sunday, Aug. 22, Kathleen McDonough, Department of Civil and Environmental Engineering, presenting) The lazy flow of the Hudson and Grasse Rivers in summer belies their elevated release of da...Congress to fund Sequim-based coastal security research effort
.... Additionally,they will develop and improve ocean transport computer models that can analyze where a signature came from and predict where it's going. PNNL scientists will draw upon existing technologies and capabilities at the Sequim laboratory, as well as PNNL's research facilities in Richland and Seattle. ...Asian elephant sex pheromone transporter revealed
...agues report an unexpected finding about pheromone transport in the Asian elephant, an endangered species of wh...hmen behavior. Use of albumin in urinary pheromone transport is distinct from other mammalian pheromone transport systems studied so far. Furthermore, the exploi...Plumbing trees' plumbing reveals their engineering skill
...djust its anatomy and physiology to maximize water transport deep underground where the plant is less likely to... insights will improve theoretical models of water transport within trees. "If you're building a model of water transport and you don't take into account these d...Newly discovered protein may be key to muscular dystrophy
...ed too long and degenerate if the protein fails to transport the neurotransmitter acetylcholine away from the nerve-muscle synapse. Muscle degeneration is the hallmark of muscular dystrophy, one of the most common genetic diseases. The study was carried out in the roundworm, C. elegans, an animal which h...Ecologists help keep death off the roads
...andscape. According to the researchers: "The dense transport system results in high mortality. This gives clear management directives for dealing with reintroductions of lynx in Germany."...UCR earns $1.5 million grant to examine how engineered crop genes stray
...on human elements, including farmer management and transport of seed through local and international trade. The third team will employ state-of-the-art mathematical and computational modeling to estimate the timing and patterns of the spread of transgenes across space and national borders as well as their e...