Harvard, Duke Researchers Discover 'Off-switch' Inside Human Cells
...damentally new route to regulating cellactivity to treat heart disease, neurological disorders and other medicalproblems, say the researchers. In a report in the Sept. 12 Nature, the researchers reported discoveringa protein called RGS10 in human cells that seems to turn off, or desensitize,G proteins. G...Newly Discovered Gene Halts Cell Division and May Have Cancer Link
...ay open the door to finding more effective ways to treat such tumors. "We think the MAD2 gene stops cells ... inactivate the checkpoint in tumor cells and then treat those tumors with spindle inhibitors. The research is supported by grants from the National Scienc...... such as in planning for precision neurosurgery to treat cognitive dysfunctions mapped to a specific brain site....Proteins Interacting With RNA And DNA Are Surprisingly Similar
...ly. Consequently, the antibiotic, which is used to treat earinfections inanimals, can be administered only externally, as a salve. "But you can't do that for an internal infection, such astuberculosis,"Draper said. A water-soluble antibiotic that worked the same wayasthiostrepton could be administered oral...Laser Microscope At Cornell Images Serotonin In Live Cells
...e antidepressant Prozac (fluoxetine) is thought to treat depression by inhibiting re-uptake of serotonin into cells from which secretion occurs. The Cornell technology may be useful in gaining an understanding of a broad spectrum of physiological and psychological effects of this -- and other -- neurotrans...Blood Test Can Identify Some Children With Strep-Related Behavioral Disorders
... rare opportunity to catch a disorder early and to treat itaggressively," she said. Swedo urges doctors who... young people for strep, and ifstrep is present to treat it with penicillin. In some cases, OCD or tics willabate when a child is treated for strep throat, s...Ten Years of Progress For Superfund Basic Research Program
...n't have to concentrate theirsamples. "The less we treat the sample, the morecontamination-free it's going to be," summed up Caruso. Researchers in the College of Medicine will also present theirfindings concerning the molecular and biochemical mechanisms ofdegradation and the mutagenesis of toxic metals. ...Erodible plastic microspheres could be effective oral drug delivery system
...insulin, growth hormone, anderythropoetin (used to treat anemia) are examples of drugs that would benefitfrom this new form of oral delivery. The delivery of corrective gene sequencesin the form of plasmid DNA could provide convenient therapy for a number ofgenetic diseases such as cystic fibrosis and hemo......to a potential new target for therapeutic drugs to treat hepatitis C," said the principal investigator, Dr. Michael G. Katze (kates), UW professor of microbiology and associate director of the UW's Regional Primate Research Center. The UW's Office of Technology Transfer has negotiated a patent-base...NIH Team Discovers Endocrine Tumor Gene
...des a target for the design of drugs to prevent or treat both benign and malignant endocrine tumors. The MEN1 gene, a tumor suppressor gene--a gene that inhibits abnormal cell growth--intrigues researchers because it is unlike any of the tumor suppressors currently known, according toAllen Spiegel, M.D., s...Project Shows Native Bacteria Can Destroy Widespread Pollutant In Groundwater
... it is one of the most widespread and difficult to treat groundwater contaminants in the country. The researchers -- working at Edwards Air Force Base in Southern California -- have completed the first full-scale test to determine if TCE can be removed from groundwater using a method called in situ biore...Emory Researchers Advance Gene Therapy Studies For Metastatic Melanoma Treatment
...esearchers believe it might be used to effectively treat advanced cases of melanoma. In gene studies on m...nter are developing a new protocol using GM-CSF to treat patients with advanced melanoma in the very near future. "The most effective strategies for treati...Duke Study Shows Early Marrow Transplant Key To 'Bubble Boy' Disease Cure
... conservativewhen compared with recent attempts to treat SCID in utero. Neonatal treatmentbypasses the instrumentation risks associated with pre-term treatment, shesaid....Duke researchers find existing drugs can stop fungus that attacks AIDS patients
... discoveredthat an existing class of drugs used to treat organ transplant recipientsmay also help fight a t...sive drugs cyclosporin and FK506,which are used to treat organ transplant recipients, prevent C. neoformansfrom growing at body temperature, but not at room ...New Evidence For Corn's Ancestry Could Lead To Insect And Drought Resistant Crops
...hey are goingto have an outbreak, they now have to treat all their fields with extremelytoxic chemicals." Tripsacum is drought resistant too, and Eubanks plans to testher experimental hybrid for that trait as well. Moreover, her Tripsacum -teosinte hybrids are perennials, and couldconceivably be explo...Scientists Bridge Gap In Cell Communication
...lications for the development of new strategies to treat diseases caused by malfunctioning genes or disrupted pathways of communication. Communication -- or miscommunication -- between cells is the basis for many diseases. For example, in humans it is believed that there are many layers of genes ......developing countries. Antibioticscurrently used to treat TB manage to prevent growth of the bacteria, but thelong-term drug treatments needed to cure the disease give the organism time tomutate into new, resistant forms. Making treatment even more difficult is thefact that many TB sufferers stop taking ant...... for DNA testing sometimes outstrips the abilityto treat any disorders that may be discovered. Is it better toknow and not be able to do anything about it or to be ignorantof one's predisposition for a genetic illness? In Does It Run in the Family?, VirginiaTech Professor Doris Teichler Zallen gives peo...Insulin Resistance Is A Risk Factor For Atherosclerosis In Whites And Hispanics
...rs could prescribe drugs already onthe market that treat insulin resistance. The study marks an expansion in the use of ultrasound to detect diseasebefore symptoms appear. "Typically ultrasound is used on sick people," Howardsaid. "But it's also a good device to measure disease in the generalpopula...