Dog Blindness Gene May Help Humans
...t advances in genetic therapy may allow doctors to treat retinitis pigmentosa (as well as rod-cone degeneration indogs) by cloning the normal gene, inserting a copy into a transfer vector such as a harmless virus and injecting thegene-carrying vector into the back of the eye. The transfer of the normal gen...UPMC Researchers Report On Gene Therapy Advances
...hase of this research in humans is not designed to treat disease, butto ensure the safety of the procedure ...both IL-1 and TNFa, suggestthat gene therapy might treat not only local, but systemic diseases, includingosteoporosis and RA. Research using muscle cells to...Jefferson Researchers Use Gene Therapy To Treat Rare, Inherited Brain Disease
...r the first time attempting to use gene therapy to treat Canavan disease, a rare, fatal metabolic brain dis...inical trial. To date, the Jefferson team plans to treat four Canavan disease children. The therapy will consist of a ventricular catheter implanted under th...UNC-CH Researchers Discover Key Cancer Control Mechanism
...ay. After more research, it might bemanipulated to treat cancer more successfully or detect it earlier. "While this work is not a cure for cancer, it is very important forseveral reasons," said Dr. Yue Xiong, assistant professor of biochemistry at theUNC Lineberger Comprehensive Cancer Center. "Fi...Research Indicates Molecule Sabotage May Slow Brain Cancer
...s a tumor. "Gliomas are exceptionallydifficult to treat because their cells have an unusual ability to travel longdistances through normal brain tissue and set up new tumors," says Hockfield. "One approach to controlling the cancer would be to block the glioma cells'ability to travel, without harming heal...Pitt Researchers Develop Strategy To Use Dendritic Cells To Treat And Prevent Tumors
...ially be adapted for usein the clinical setting to treat patients," commented Louis D. Falo, Jr., M.D.,Ph.D., assistant professor of dermatology, vice chairman of dermatology at Pittand member of the University of Pittsburgh Cancer Institute (UPCI). "Usingtumor cells taken from patients, we may be able to...One Year Follow-Up Of Non-Invasive Angina Treatment Suggests A Lasting Benefit
...y also tended to use less of their nitroglycerinto treat their chest pains," Chou says. With EECP, pressure cuffs wrapped around the patient's legs and buttocksare used to pump extra blood to the ailing heart muscle while the patientreclines. Inflation of the EECP pressure cuffs, an event t...Can The Economic Promise Of Drug Discovery Continue To Preserve The Suriname Forest?
... began to work in Suriname todiscover new drugs to treat human ills and to give the country reasons topreserve the diversity of its forests -- combining the ancient knowledge ofshamans with modern chemical screening techniques and biotechnology. So far, theresearchers have identified one novel compound wit...Hard Hearts: New Discovery Of Bone In Heart Tissue May Explain Valve Disease
... lead to the development of therapies toprevent or treat heart-valve disease. The broader problem of valve calcificationis the leading reason for heart-valve-replacement surgery. According to theAmerican Heart Association, more than 71,000 Americans required the life-savingprocedure in 1995. This ...Evaluation Of The Two Types Of Cardiac Pacemakers Indicates Only Modest Differences In Value
Implanted cardiac pacemakers have been used to treat people with slow heartrates for more than two decades. But until recently there had never been acomprehensive evaluation made of the quality of life associated with the twodifferent forms of the therapy. As a result, discretion on which to use has ...Naturally Produced Enzyme May Be Useful In Inflammatory Arthritis
...earchers have discovered a potential method tohelp treat inflammatory forms of arthritis by using an enzyme naturallyproduced by the human body. Researchers found that the enzyme neutral endopeptidase (NEP) couldreduce some of the effects of inflammatory arthritis, according to a studyin a recent iss...Chocolate Treats Can Land Racehorse Trainers In Trouble
COLUMBUS, Ohio -- Chocolate may be a harmless treat for humans, but itcould land a competitive racehorse into trouble with officials. Researchers at Ohio State University found that three horses fed a vending-packof M&M’s® chocolate-coated peanuts every day for eight daysshowed detectabl...Jefferson Scientists Devise Way To Treat Animals Chronically Infected With Hepatitis B
...een approved by the Food and DrugAdministration to treat HBV. Recently, a drug called lamivudine has beenapproved to treat the disease. However, the virus can become drug-resistant. Dr. Block notes that the drug wor...New RNA Repair May Lead To More Successful Gene Therapy
...ope that one day we will be able to cure - notjust treat -- beta thalassemia, an inherited deficiency of hemoglobin, theessential protein that carries oxygen and gives blood its red color," said Kole,a member of the UNC Lineberger Comprehensive Cancer Center. "We are still a fewsteps away from trying this ...Pediatric Academic Societies Report Progress In Children's Health
... system. The next step is to apply the approach to treat laboratoryanimals with diseases mirroring human disorders, he said....High-Pressure Chambers Could Prevent Paralysis After Spinal Cord Injury
WASHINGTON D.C. -- High-pressure chambers used to treat deep sea diversfor decompression sickness could play a key role in preventing permanent spinalcord damage and paralysis to many of the thousands of Americans who sufferspinal cord injuries every year, a doctor from Scotland reported today. Dr...Study Highlights the Use of Viruses as Tools for Material Science and Drug Delivery
...ance similar to heparin--which isroutinely used to treat coronary thrombosis--into cowpea chlorotic mottle virus. Because this phenomenon of gating is possible for a large number of viruses ofdifferent shapes and sizes, there is no reason to think that options for drugdelivery are limited to any particular...15 Drugs, Dyes And Other Chemicals Newly Listed As Known Or Likely Human Carcinogens
...n immunosuppressive drug. THIOTEPA, a drug used to treat lymphomas and tumors of the breast andovary. It ha...be Human Carcinogens: AZACITIDINE, a drug used to treat acute leukemia. p-CHLORO-o-TOLUIDINE and its HC1 salt, used to produce azo dyes forcotton, silk acet...Gene Detected That Decreases "Bad" LDL Cholesterol In Men May Cut Heart Disease Risk By 50 Percent
... in the field of drugdevelopment. Most drugs that treat high cholesterol work by removing excessamounts. However, the MTP variant helps reduce production of LDL. Some drug companies have already begun looking at MTP inhibitors, tohelp lower LDL. Even though the study was conducted in men,......nt andcommercialization of products to prevent and treat cancer....