New study shows hope for treating inhalant abuse
...ime "seeking" toluene in that location after being treated with GVG than animals treated with a placebo. This elimination of conditioned place preference -- a model of craving in which anim...International study findings link acne-like rash to effectiveness of new targeted cancer treatment
... 346 patients with advanced colorectal cancer were treated in the study in Leuven and other Belgian and U.S. centres. All the patients had metastatic cancer and had failed to respond to at least two prior chemotherapy regimens, although all still had a reasonable quality of life, either being fully active or...Chemical derived from vitamin-E shows early promise as cancer drug
...eclinical animal models. Mice in the study were treated with alpha-TEA for 21 days after an injection of m... to five of 10 untreated control mice. None of the treated animals showed any type of general symptoms of toxicity to alpha-TEA, which Kline chose for further ...Award winning researchers reveal potential new role for Glivec
...nical responses to imatinib. The ten patients were treated with 800mg of imatinib daily. Of the eight with locally advanced disease, two achieved complete response that was pathologically confirmed through resections of the regions where the tumour was present and two achieved complete response confirmed by ...Trial shows which brain cancer patients benefit from temozolomide
...lioblastomas are likely to live longer if they are treated with temozolomide, and which patients are likely t...In this tested group 106 of the patients have been treated with radiotherapy and temozolomide. There was a 46% survival rate at two years for the 46 patients i...Preclinical safety study shows adipose-derived stem cells improve heart function after heart attack
...action (LVEF) at six-months post-infarction in the treated group over the control group, as measured by 2D echocardiography. Similar trends were observed by measuring LVEF via cineangiography, as provided in the data table below. LVEF is a measure of the heart's ability to pump oxygenated blood throughout th...Knock knock knocking on rhythm's neural doors
...l models, notes that researchers have historically treated both kinds of movement as fundamentally the same in terms of control -- to say that one is a special form of the other. Thus specialists studying discrete movement have considered rhythm a subset of discrete movement -- the same thing speeded and rep...Enzyme maintaining chromosome ends is linked to bone cancer recurrence, decreased survival
...ted with an unfavorable outcome for children being treated for osteosarcoma," said Jeffrey S. Dome, M.D., ass...samples taken from osteosarcoma tumors of children treated at St. Jude during a 20-year period. Telomerase is an enzyme that helps cancer cells survive and pr...A novel, safer strategy for regulating gene expression
...ut the development of leukemia in several children treated with gene therapy, this new method adds an importa...ded ribozyme, into the retinas of mice. When they treated the mice with a ribozyme-inhibiting drug, the gene turned on and the animals' retinas began producin...Study explores gene transfer to modify underlying course of Alzheimer's disease
... in the study. The first patient in the study was treated on July 27. Dr. David Bennett and Dr. Zoe Arvanitakis of the Rush Alzheimer's Disease Center are the co-principal investigators. Bennett is director of the center. Ceregene, Inc., based in San Diego, (a minority owned subsidiary of Cell Genesys, Inc....Experimental drug shown to block mutant protein causing blood disease
...ancer drugs. In the study, mice with MPD that were treated with the oral compound PKC412 significantly outlived those given a placebo. When tested in a single patient, a 52-year-old woman with MPD, the drug reduced her dangerously high white blood cell count and shrank her enlarged spleen and lymph nodes. Ho...USC study links historical increases in life span to lower childhood exposure to infection
...redisposed to heart disease, for example, could be treated starting at a much younger age. "These people would have a special lifestyle recommendation from the earliest years," Finch said. "We noticed that improvements in the environment may be reaching a maximum which would mean that further increa...JCI table of contents September 15, 2004
...her showed, using microarray analysis, that in the treated retinas, several genes that showed increased expression were genes involved in blocking cell death. Taken together, the data from this study indicates that regardless of the underlying genetic defect, the relationship between retinal vasculature and ...Byproduct of water-disinfection process found to be highly toxic
...ction byproduct (DBP) found in U.S. drinking water treated with chloramines is the most toxic ever found, say... in chloramines-treated water, 28 percent in water treated with chlorine-dioxide, and just 8 percent in ozone-treated water. Of the structurally identified DB...Molecule awakens and maintains neural connections
...s a receptor comes from an experiment in which Shi treated neurons with a molecule that mimicked Dasm1, but in which the portion of the molecule that extends into the cell had been replaced by a segment from another protein rendering it unable to interact with Dasm1's usual partners inside the cell. This tr...New treatment for fibromyalgia
...ss to tenderness--the female fibromyalgia patients treated with duloxetine improved significantly over those treated with a placebo. One of the most dramatic changes was in the reduction of the number of tender points...The impact of genetic variations on the treatment of early rheumatoid arthritis
...immune disease. Traditionally, patients have been treated with disease-modifying antirheumatic drugs, or DMA...orrelated with treatment responses. Among patients treated with standard-dose etanercept, those with two copies of the shared epitope were four times more like...Novel IBD therapeutic approaches reported from Washington Univ., Barcelona, LSU at APS meeting
...both clinically and by histological criteria. Mice treated with CTLA-4-Ig and TNBS had a 100% survival rate and a significant reduction in colonic TNFmRNA expression regardless of IDO inhibition. IDO inhibition with 1-methyl-tryptophan (1mT), however, prevented colitis abrogation by CTLA-4-Ig both clinically......mal intestinal lining cells. When the embryos were treated with retinoic acid, normal cell development was restored. Because zebrafish and humans share many genes, including the APC gene, researchers often use the little black-and-white striped fish as models to study various aspects of human development. ......hat Compound 3 also switched on apoptosis in cells treated with TNF alpha. Thus, said Wang, Compound 3 might ...e that, for example in rheumatoid arthritis, if we treated with something like Compound 3, it would cause TNF alpha to trigger apoptosis in the cells that caus...