Light turns on anticancer agents
...der to not harm innocent tissue while aggressively treating diseases such as cancer with powerful medicine, scientists have been creating therapy agents that they can activate with light only at the site of a tumor. Until now, almost all photodynamic therapy agents have required oxygen. Yet, tumors are often...In gene regulation, small is beautiful
...s that would be critical if ATFs are to be used in treating disease. Next, Mapp's group plans to investigate exactly how their artificial activators work. "We haven't rigorously proven that they function by the same mechanism as natural activators, but they seem to be quite analogous," she said. The researche...Sweet success in targeting sugar molecules to cells in living animals
...the resulting "azido sugar" on the cell surface by treating it with a molecule called a phosphine to which any desired molecule, such as a probe for visualization, can be attached. This reaction, called the Staudinger ligation, is "bio-orthogonal," said Bertozzi -- meaning that it does not affect the cell's b...When is a mouse like a test tube?
... (azidothymidine) and phosphine-gold compounds for treating arthritis. Bertozzi figured that if she could attach an azide to a natural sugar and feed it to cells, she could insinuate the sugar into the sugar polymers (oligosaccharides) that decorate the exterior of cells, then use the Staudinger ligation to ...Nerve cells 'guided' to repair spinal damage: Technique
...te nerve cell repair that could ultimately lead to treating severed spinal cords. The technique, outlined in the July 6 online version of Biomaterials, involves imbedding a series of fibrous rods into a gel substance and then dissolving the rods, leaving a series of longitudinal channels. These channels are ...Alcohol-use and depression among pregnant and postpartum women
... "This not only provides further justification for treating these disorders together, it also indicates that f...ategies that address both these issues, instead of treating them separately and in isolation from each other. They may be causally linked. That is, women may ...Gene changes linked to increased eye pressure may have implications for glaucoma therapy
...de, and the new findings may have implications for treating this disease. The study currently appears in the online October issue of the Journal of Cellular Physiology . "Pressure is required in the eye to keep its shape, and this pressure is maintained in the front part of the eye by a fluid, the aqueou...Body's own defense against H. pylori, cause of stomach ulcers and stomach cancer
...ine, these results present a new way of looking at treating chronic inflammation associated with stomach ulcers, and introduces the possibility of preventing stomach cancer associated with H. pylori. Over fifty percent of the world's population is infected with H. pylori, yet only 2% are aff...Tobacco promising factory for biopharmaceuticals
...nant proteins are potential therapeutic agents for treating human and animal diseases and creating new vaccines. Plant-made vaccines are especially beneficial because plants are free of human diseases, reducing the cost to screen for viruses and bacterial toxins. "Recombinant protein production from transgeni...Joslin Diabetes Center launches research section on developmental and stem cell biology
...at stem cell research holds tremendous promise for treating a variety of diseases, including diabetes. There a... of such cells may have important implications for treating many of the long-term complications of diabetes. In addition, this comprehensive analysis of adult ...Newcastle scientists get UK's first stem cell license
...ly contribute to advancements in understanding and treating debilitating disease, but will lead to job opportunities in the region and attract and retain talented researchers." ...Scientist who discovered Sly syndrome finds new research path to explore for treating the disease
...he missing enzyme into the body - holds promise in treating physical problems caused by mucopolysaccharide acc...d that enzyme replacement therapy was effective in treating the brain if given while the mice were very young. "Until now, the reason why the central nervous s...New prostate cancer gene identified
...s us the opportunity to explore a new path towards treating a significant number of men with advanced prostate cancer. As TGen's mission is to translate laboratory findings into the clinic, we hope to use this information to ultimately help provide prostate cancer patients more treatment options and a better...Viral proteins may prevent bacterial infections
... these enzymes also makes them good candidates for treating infections as well. As they are larger molecules than antibiotics, Fischetti is unsure whether they can reach everywhere in the body that antibiotics do. "Until we do more animal studies we don't know how these enzymes will be distributed throughou...Babies with DiGeorge syndrome saved by immune supression, thymus transplant
...be rejected. Building on 12 years of experience in treating DiGeorge syndrome, Louise Markert, M.D., associate professor of pediatrics at Duke University Medical Center, and her colleagues found that quashing the rogue T cells with an immunosuppressant drug given for three days immediately before transplant s...Study: A little help from friends makes wounds heal faster
..., the researchers experimented with the effects of treating two groups of socially isolated hamsters with either oxytocin or a substance that blocks oxytocin production. Hamsters in the oxytocin treatment group were given oxytocin injections daily for five days prior to wounding and restraint stress, while co...JCI table of contents, 2 August, 2004
...these data into the context of the difficulties of treating stroke victims, and what additional information be...ow these data will be useful for understanding and treating stroke patients. TITLE: Administration of CD34+ cells after stroke enhances neurogenesis via angioge......these data into the context of the difficulties of treating stroke victims, and what additional information be...ow these data will be useful for understanding and treating stroke patients. ...Genetic discovery could dramatically reduce need for liver transplants in children
...e total annual cost, including transplant care, of treating all infants with biliary atresia is estimated to be $65 million. In a previous study published in The Lancet, Dr. Bezerra obtained biopsies of livers of 14 infants with biliary atresia. Using gene chip technology, he and the Cincinnati Children's res...'Smart gene therapy' protects against damage from heart attack
...r a significant advance over available methods for treating heart patients, which are limited in their ability to provide treatment in the narrow window of time before irreversible heart damage occurs, he said. The work, led by Dzau at Brigham and Women's Hospital prior to his move to Duke in July, was suppor...