New Cancer Switch Discovered By Duke Medical Center Pharmacologists
...bility allows cancer cells to survive chemotherapy treatments that would kill normal cells. Reporting the findin...st, the discovery offers the possibility of cancer treatments that eliminate drug-resistance by selectively rendering tumor cells vulnerable to normal cell death ...Tumor Suppressor Gene Located In Liver Cancer Cells
...y and cancer center member. The lack of effective treatments also makes it a particularly deadly disease, he said. "As a consequence, knowing something about liver tumor formation or having a handle on how one could detect these tumors when they're much smaller could have a significant impact on survival," he ...Florida Researchers Discover Gene For Fatal Childhood Disease
...ully by understanding the gene we can forge better treatments forChediak-Higashi syndrome, and in the long run o...e spread of cancercould lead to new medications or treatments for all cancer patients, he said. Meanwhile, researchers discovered that mice with Chediak-Higas...Protein Glitch May Be Early Problem In Inherited Alzheimer's
... it, intervening at this point with drugs or other treatments might be ideal, according to Sangram Sisodia, Ph.D., an associate professor of pathology and neuroscience. Sisodia and Gopal Thinakaran, Ph.D., David Borchelt, Ph.D., and Michael Lee studied presenilin in cell cultures and in mice that contained cop...Animal Studies Indicate Aging Brain Responsive To Estrogen
...opic studies that allowed themto determine how the treatments affected neurons called granule cells inthe rats' hippocampus, a brain region involved in spatial memory. The scientists'study of single neurons revealed that the rats exposed to acute estrogentreatment had 40 percent more connective elements, called...No Such Luck: Nitrogen From Air Pollution Unlikely to Moderate Global Warming
...al areas of Europe," said Tilman. "Two of our nine treatments went beyond these rates to try to predict the longer-term effects of nitrogen deposition." Tilman and Wedin found that more than half of the plant species were lost across the nitrogen addition gradient, with the greatest losses occurring at ...New Nonviral Gene Therapy System Could Help Fight Cancer
...ve the negativeside effects of some current cancer treatments because onlydiseased cells are attacked. "This is the benefit of this technique over chemotherapy,"he said. "Chemotherapy kills all cells on contact, even healthycells. The T7 system allows for a more selective treatment thattargets only the ca...ORNL Finds Common Genetic Cause For Epilepsy, Migraine
...improvediagnosis and may aid in development of new treatments for migraine. In addition to the role of genes suggested by family-, twin- andpopulation-based studies, such other factors as emotional stress and certainfoods and additives have been associated with migraine attacks. Isolation of the human episodic ...Blood Test Can Identify Some Children With Strep-Related Behavioral Disorders
... combined with behavior modificationtherapy. These treatments target control of symptoms, not elimination ofcauses. Medical personnel often consider the onset of tics or other involuntarybehavior in children to be the result of parental pampering and coddling, saidPatricia Moore, president of the Rhode Island...Children With AD/HD Have Significant Functional Disabilities Related to Attention Deficit
...ed in a broader study, they should be the focus of treatments in children with AD/HD, Lock stated. Other researchers involved in the study were Nadine L. Duchan, Sue E. Olexenko, and Michael E. Msall, of the UB Department of Pediatrics. The study was sponsored in part by the Children's Guild of Buffalo....Researchers Find Production Point Of Key Protein In Fragile X Syndrome
...ss synapses are deleted. While stressing that new treatments for fragile X syndrome won't immediatelyresult from the findings, Greenough said, "The knowledge allows usto focus on a particular aspect of the brain and its development in effortsto better understand the disorder." "It had been known from studies ...Duke researchers find existing drugs can stop fungus that attacks AIDS patients
...erature. "It is difficult to find effective treatments for fungal infectionsbecause fungi, unlike bacteri...earchers have tested many calcineurin inhibitorsas treatments to prevent organ transplant rejection, Heitman tried severalthat had been rejected as organ transpla...Scientists Bridge Gap In Cell Communication
...t may lead to the development of new genetic-based treatments for disease. It also reveals that the pathway from cell surface to the gene is remarkably direct. CONTACTS: Allen Laughon , (608) 262-2456, alaughon@facstaff.wisc.edu ; Sean Carroll , (608) 262-6191, sbcarrol@facstaff.wisc.edu...Jefferson Scientists Discover Mechanism Of Viral Link To Disease Commonly Associated With Asbestos
... team is pursuing research that may lead to new treatments for mesothelioma and lung cancer. The team hope... to determine mesothelioma in early stages, and treatments that will allow the genes to restore normal function." The SV40 findings are the lates......gs, anunexpected finding that can help develop new treatments that specificallyinhibit this function. "...vent growth of the bacteria, but thelong-term drug treatments needed to cure the disease give the organism time tomutate into new, resistant forms. Making treatme...E. Coli Genome Reported: Milestone Of Modern Biology Emerges From Wisconsin Lab
...enetic aspects of all disease, leading to improved treatments and even cures. The NHGRI, a component of NIH, is a major partner in the Human GenomeProject, the international research effort to map the estimated 50,000 to100,000 genes and to read the complete set of genetic instructions encoded inhuman DNA. N...Imaging Studies Illuminate Brain's Response To Cocaine
... rush versus the craving experience - oras broader treatments for cocaine abuse and addiction." Additional funding forthis study was provided by the National Heart, Lung, and Blood Institute and theNational Alliance for Research on Schizophrenia and Depression.......velop a cost-effective screening test and identify treatments for the sick veterans." The agreement between UT S...t but cannot cure diabetes, we believe we can find treatments to allow these Gulf War veterans to live more comfortable and productive lives."...Further Proof That An Altered Rb-2/p130 Gene Leads To Lung Cancer
...nts. This information can help physicians begin treatments earlier, and tailor them to specific patients, depending on how aggressive the cancer is. “Now a tumor grading test is much closer to reality,” said Giordano, who is also president of the Sbarro Institute for Cancer Researc......d by other studies, clinical trials to develop new treatments toreduce triglyceride levels might be worthwhile," says Gaziano. "Ultimately,screening and treatment guidelines may require modification to allow greaterattention to be paid to fasting triglycerides." Gaziano and colleagues compared triglyceride and...