Duke Researchers Discover Candidate Susceptibility Gene For Autoimmune Disease
...ings support preliminary results of human clinical trials beingconducted at Duke and other research institutions of an experimental treatmentfor rheumatoid arthritis (RA) that also uses antibodies to TNFa, Blackshearsaid. Such studies have shown antibodies to TNFa can significantly reducethe symptoms of RA ...Nutrition Study Reshapes Strategies For Athletes
...r Kersee fell victim to dehydration during theJune trials in Atlanta, a rare error in athletes at that level. The other key, Houtkooper says, is eating enough of the right kinds of foodsand eating them on a schedule coordinated with their competitions. Lighteris not necessarily better, which flies in the fa...... Promising results have been reported from Marquis trials in Arkansas, Indiana, and Michigan. A Cornell tri... Valley has been very successful. Semi-commercial trials are being prepared in southwest Michigan. Because there is international interest in large-berried s...Hawaiian Whales Show 'No Overt Response' To Sounds Of ATOC Simulation
...re just another noisy day in the ocean. "In 84 trials beginning in February and continuing through March off the Kona-Kohala coast of Hawaii, we saw no overt response from the whales. For example, a cow-calf pod remained about 100 meters from our playback boat throughout an entire playback," said Ad...Jefferson Scientists Discover Mechanism Of Viral Link To Disease Commonly Associated With Asbestos
... studies and is about to enter phase 1 clinical trials in humans. Dr. Giordano was the first to identify and clone the pRb-2/p130 gene and demonstrate that it could halt the growth of tumors. He has been studying the family of tumor-suppressor genes for nine years. "The findin...Gene Shears In Cutting Edge Anti-Aids Trial
...onary "gene shears" technology has enteredclinical trials in adults as the first step in developing a potent...SIRO, Dr Malcolm McIntosh, welcomed news thathuman trials of the anti-HIV gene shears were under way. "It is extremelypleasing that this fundamental Australi...New Gene May Intensify Breast Cancer Growth
...ied in breast cancer have led toclinical tests and trials of therapy. AIB1 may turn out to be a new candidatefor similar development, Meltzer noted. NHGRI oversees the NIH's role in the Human Genome Project, an internationalresearch effort to develop tools for gene discovery....Trojan Horse Virus Controls Hiv Infection
...es thepossibility is at least a year away and that trials in animal models are anecessary first step. The report says the novel VSV described would be most appropriate for limitingHIV production in people with late-stage disease, but the Yale team has moved onto develop VSV constructsthat incorporate other ...Oral Vaccine Protects Infants From Severe Rotavirus Diarrhea
...ve been intimately involved with the many clinical trials done totest several rotavirus vaccine candidates. Initially, Dr. Kapikian, Robert Chanock, M.D., chief of LID, and theircolleagues developed a monovalent vaccine against rotavirus in1984. Two years later, when it was considered that a monovalent vac...Triglyceride Blood Levels Predict Heart Attack
...rt diseaseare confirmed by other studies, clinical trials to develop new treatments toreduce triglyceride levels might be worthwhile," says Gaziano. "Ultimately,screening and treatment guidelines may require modification to allow greaterattention to be paid to fasting triglycerides." Gaziano and colleagues...Folic Acid Fortification Effective In Cereal Grains
...ts, who were 20 to 35 years old, participated in 7 trials of folic acid intake. Each individual had normal b...stream. The investigators conducted the final two trials tostudy a liquid supplemental dose of folate consumed either with or without a light breakfast. The ...Chlamydia Vaccine Developed At UMass
...ears perhaps as long as a decade before clinical trials are completed that could bring governmental approval for the vaccine. Current work is focusing on development of a nasal vaccine as an alternative to a strictly oral medication. Stuart and MacDonald worked together on the research beginning i...UPCI Researchers Find Drug Improves Cancer-Fighting Ability Of Vitamin D
...ncer in animals, and we have conducted preliminary trials of this agent in men with advanced prostate and other cancers. However, the use of 1,25-D3 has been limited because this drug causes a potentially life-threatening increase of calcium in the blood," said Donald Trump, M.D., an investigator on the st...Maillinckrodt Medical Licenses Invention For Concentration Of Rhenium Radioisotopes
...tenosis, rhenium-188 is used in physician-approved trials in collaboration with ORNL for the treatment of bone pain from skeletal metastases of cancers of the breast, lung and prostate. The clinical application of rhenium-188 for coronary artery irradiation has been approved by the U.S. Food and Drug Admini...Handfish Steps Back From Brink Of Extinction
...ape extinction as a result of successful breeding trials and research into its biology. "We believe we now have the techniques to proceed with developing a larger-scale breeding program for this and other related handfish species if required," said Barry Bruce, a biologist at CSIRO’s Division o...New Company To Turn UNC-CH, Army Inventions Into Improved Vaccines
...ions, he said. "Getting ready for clinical trials is a tremendously expensive processthat isn't always practical in a university setting," Johnston said. "Now wewill be able to see our experiments through, from the earliest laboratorystudies to the final tests of safety and efficacy in humans. And t...Experimental Trial Combines DNA Vaccine With Triple-Drug Therapy To Stop HIV
...professor ofmedicine and director of AIDS clinical trials at the Hospital of the Universityof Pennsylvania. MacGregor is principal investigator on the trial. "Also, we'reusing a broader-based, possibly more effective vaccine than in our earlierstudy, one that contains genetic material from four different HI...Timber Supplement From Paper And Plastic
...ct leader Dr Bob Coutts says that industrial-scale trials have begun with a paper/plastic product and it shows promise of being suitable for some applications that currently use timber. "Basically the ingredients are any waste thermoplastic material and waste paper," says Dr Coutts. "The paper,...Gene Therapy Enables Transplantation Without Immunosuppressive Drugs
...imal studies will be required before humanclinical trials of the approach can be considered, the advantages of such alocalized system for countering the immune-system rejection of newly engraftedorgans are potentially significant. The powerful immunosuppressive drugs nowrequired to allow a life-saving trans...Calcium Potentiates The Effect Of Estrogen And Calcitonin And Bone Mass
...n in the United States.This review of 20 published trials shows that bone health is best preservedin postmenopausal women who use a combination of estrogen replacement and atleast 1200 mg calcium daily, rather than either treatment alone....