Tag: "trick" at biology news

NHGRI study may help scientists develop safer methods for gene therapy

...he NHGRI researchers developed a simple laboratory trick for easily identifying the insertion site by capturing and then sequencing a small bit of the human genome immediately adjacent to where the retrovirus inserted. "Now that a high-quality, finished copy of the human genome is available in public data...

Deciphering how arteries contribute to hypertension

...pulmonary hypertension. Could there be some way to trick the arterial walls so that they wouldn't stiffen under increased blood pressure? Working with the Children's Hospital and University of Colorado Health Sciences Center in Denver, NIST researchers have used rat arteries--both normal and hypertensive--...

'Immortalized' cells enable researchers to grow human arteries

...to form an artery in the laboratory. So we stole a trick cancer cells use to keep dividing; namely we turned on hTERT to stop telomerase shortening." The researchers did not detect any signs of unwanted cellular proliferation in their bioengineered arteries, although Counter did emphasize that before these...

'Work stinks': It's more than just a slogan among ants, researchers find

...rizona. The scientists wanted to see if they could trick foragers into leaving a colony by enticing them with tiny beads that smelled just like patrollers. To accomplish that, researchers would arrive at the nests early each morning and round up all of the patrollers before they had a chance to return home...

Researchers developing 'sentinel plants' to warn of bioterrorism

...soil. In essence, it's telling you, 'Feed me.' The trick is to design plants that respond in particular ways to particular stimuli, and to amplify these responses so they can be detected readily." The key to manipulating plant response to environmental stimuli is to understand the role of certain genes, sa...

Tapeworm's chemical trick could make drugs more effective

...le environment, the lowly tapeworm uses a chemical trick to evade the propulsive nature of its intestinal home. Capitalizing on that tapeworm chemistry, scientists at the University of Wisconsin-Madison believe they may have found a way to slow the transit of drugs through the intestine, making them more e...

Proposed treatment for diabetes could have devastating side effects

...une response. The idea of this immunotherapy is to trick the body into tolerating the cells that it would otherwise attack by "training" the immune system to ignore the insulin producing cells instead of killing them. Earlier work had shown peptides derived from a protein known as GAD 65, that is expressed...

Researchers unwind secrets of biological clocks

...ning how the clocks actually work. It was no small trick to produce a model from a one-celled organism so simple that no one can even see just how it acts out its daily rhythms of life. The organism doesnt even have a nucleus, after all, much less a discernable daily routine. So Golden, a molecular biolog...

Puzzle solved on how influenza builds its infectious seeds

...rugs to combat the disease by exposing the genetic trick it uses to form virus particles. The new work is reported by a group led by Yoshihiro Kawaoka, a professor of pathobiological sciences at the University of Wisconsin-Madison School of Veterinary Medicine, who has a joint appointment at the University...

Deadly coral toxin exposes ion pump's deepest secret

...d - until now. Presto, you're an ion channel! To trick the sodium/potassium pump into revealing its true "ion channel"nature, Artigas and Gadsby applied palytoxin to cells and usedelectrophysiology - specifically the "patch-clamp" technique - to detect itseffects. The patch-clamp technique has enabled sc...

Even green pond scum can suffer from jet lag

... so that plants can use it for food. It is quite a trick for a single-celled organism to combine photosynthesis and nitrogen fixation because the two processes are biochemically incompatible. The Taiwanese discovered that the tiny organisms had solved this problem by inventing the practice of moonlighting:...

Researchers identify cause of aggressive childhood cancer

...been applied to cancer modeling," said Orkin. "The trick was to make the gene we wanted to delete, instead of being excised, to flip back and forth and then randomly settle in either the active or inactive orientation." By employing this technique, Orkin and Roberts created mice whose tissues had a delica...

Targeting enzymes that immortalize cancer cells: if you can't turn them off, round them up

Berkeley - Discovery of a clever trick that cancer cells use to make themselves immortal may lead to a way to stop their unchecked growth, according to scientists at the University of California, Berkeley. In a paper published the week of August 26, in the journal Nature Cell Biology, UC ...

Rad50 and the maintenance of genome stability

...omosome repair lead to early embryonic death. The trick here was to make a more subtle mutation, and to get a viable mouse," explains Dr. Petrini. In choosing their Rad50 mutation, the researchers turned to previous work in yeast. Dr. Petrini and colleagues made a point mutation in the Rad50 gene that res...

Researchers discover how herpes tricks the immune system

...pe of herpes virus makes its own version of RCA to trick the immune system and evade destruction by complement, but that the RCA mimic proteins help the virus only during acute infection. The researchers used a mouse virus called gamma-herpes virus 68 (gHV68), which is similar to Epstein Barr virus and the...

Stanford scientists flick genetic switch; may lead to new disease treatments

... in triggering some diseases. For researchers, the trick is learning how to deactivate these genes to treat illnesses. In a step toward reaching that goal, scientists at Stanford University Medical Center have developed a gene-therapy technique to switch off genes in mice. The finding could potentially lea...

Researchers developing technology to outsmart metastasized cancers

...s selectivity, researchers have developed a way to trick cancer cells into attracting and even ingesting anticancer agents that are attached to folate molecules. As a result, these chemotherapeutic agents can be delivered more specifically to cancer cells while leaving the surrounding normal tissue unharme...

Insect yields clues to evolution of species

...tors. "Youve got to have very good camouflage to trick a bird," said Sandoval, noting that birds have very good vision and are visual predators. The insect exhibits two genetically determined color patterns. The unstriped insect is more commonly found on the plant Ceanothus spinosus (commonly called bl...

Studying the strength of protein bonds one molecule at a time

... binding is the same for each individual pair. The trick to uncovering the strength of a single bond between proteins was the use of the laser tweezers. Laser tweezers cannot manipulate individual molecules, as such, but Penn scientists developed a new model system using tiny pedestals and beads that can b...

Mathematical analysis could aid flu vaccine selection

...on of the viral surface. "It can't repeat the same trick for evading the immune system," said Levin, noting that this information also may be useful in predicting the course of flu evolution. The researchers noted that the strength of their technique depends greatly on whether the viruses recorded in the d...

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