Stem cell research targets cerebral palsy
...y different types of cells, donated stem cells may trigger an immune response, much like a transplanted organ. So Dr. Carroll also will compare the success of transplants that include the immunosuppressive agent, cyclosporine-A, to those that don't. He'll also look at the bottom line: whether the motor skill...Protective gene may enhance vaccine responses
...tes, genes that interfered with the processes that trigger cell death. Their search led them to Spi2A. Spi2A, they found, was produced in higher amounts in memory T cells. It suppressed cathepsin B, a potent digestive enzyme that can induce cell death. T cell populations in which Spi2A levels were reduced ...Last of known genes identified in complex obesity syndrome
... as to open or close the cell's entry points or to trigger relocation of "freight" within the cell. "That this type of molecule could cause BBS is particularly intriguing," says Katsanis. In additional experiments using the worm C. elegans, the researchers proved that ARL6 normally functions only in cilia, s...Leukemia stem cells identified by Stanford researchers
...y, any one of which might activate the pathway and trigger self-renewal. One goal of Weissman's lab is to identify cancer stem cells in a broad range of cancer types to learn more about which proteins go awry in these cells. Eventually, he said this work could lead to new drugs that shut down these inappropr...UCSD researchers are first to demonstrate molecular link between inflammation and cancer
...he infection. In normal mice, these two compounds trigger both inflammation and, a few months later, tumors called adenocarcinomas. In this study, DSS and AOM were given to two additional groups of mice one group bred without IKK beta in the epithelial cells of the intestine; the second group without IKK b...Early clinical treatment can halt progression of Alzheimer's disease, UCI researchers find
... accumulation of amyloid plaques is the initiating trigger of the disease process constitutes the "amyloid cascade hypothesis" a controversial theory in neuroscience. By showing that the progression of Alzheimer's can be stopped by early treatment of the plaques, the new findings strongly support the hypoth...New discovery may help transplants survive
...uch of his research to finding the mechanisms that trigger immune responses, and, in the case of corneal transplants, the "unwanted" immune response that causes corneal transplant rejection. VEGFR-3's role in activating the immune response in the cornea is the most recent in a series of discoveries by Dana a...Forest fire sensor inspired by nature
... that automatically monitor large forest areas and trigger an early warning in the event of fire. Zoologist at the University of Bonn have taken an important step towards this goal. They have constructed a forest fire sensor which could be produced more cheaply than commercially available infrared detectors,...Environment influences learning: U of T study
... becomes apparent that environmental cues can also trigger the memory of odour as a cue for starvation," said Law. "This is something people intuitively said was important. This is an important bridge between psychology and neurobiology. Affecting an environment affects your ability to learn." The resea...Gene therapy reaches muscles throughout the body and reverses muscular dystrophy in animal model
... is able to 'home-in' on muscle cells and does not trigger an immune system response. The delivery system also includes use of a growth factor, VEGF, that appears to increase penetration into muscles of the gene therapy agent. Chamberlain said the formula was the result of about a year of trying different me...Good bacteria trigger proteins to protect the gut
...his colleagues discovered that beneficial bacteria trigger proteins called Toll-like receptors (TLRs) to maintain the health of intestinal epithelial cells and to activate machinery that responds to injury. Previously, TLRs were thought to function strictly as assassins, recognizing molecules on the surface ...Hormone helps fish to mate, may affect human hearing
...s. Rather, the Cornell biologists found a hormonal trigger for a complex auditory system. Andrew H. Bass, the Cornell professor of neurobiology and behavior who led the research team that reported the findings in the July 16, 2004, issue of Science ("Steroid-dependent Auditory Plasticity Leads to Adaptive...New model explains why costly insect 'outbreaks' hard to predict
... a model that appears to untangle the factors that trigger such outbreaks, and that helps to explain why outbreaks are so unpredictable. By combining elements from two prevailing but flawed insect-outbreak theories, and supplementing the combined theory with additional data, the researchers produced a ...'Anti-plume' found off Pacific Coast
...rating downward through the Earth may be enough to trigger the growth of bacteria at startling depths. Last year, in an unrelated study, OSU oceanographer Martin Fisk and a team of researchers found bacteria in a hole drilled 4,000 feet through volcanic rock. Basalt rocks have all of the elements required fo...Brain serotonin enzyme finding might explain psychiatric disorders
...rotransmitter," a chemical that one neuron uses to trigger a nerve impulse in its neighbors. Thus, serotonin levels can profoundly affect brain function, and therefore behavior. "For the first time, we've identified a naturally occurring genetic difference that controls the production of serotonin in the bra...Study suggests first molecular target to halt spread of HPV
... E7 proteins, the virus would no longer be able to trigger cellular proliferation. "There are some unique characteristics of E6 and E7 which make them good targets, most importantly, their critical role in overcoming cell growth control pathways," said Clawson, who is also director of the Jake Gittlen Cance...Asian bird flu became highly pathogenic through continued circulation and gene swapping
... Jude. "In order to reduce the ability of H5N1 to trigger another poultry epidemic, officials in East Asia must follow Hong Kong's lead," Webster said. "Otherwise, H5N1 will likely continue to infect birds and other animals and eventually could evolve into a dangerous human pathogen as well." Webster and W...Researchers discover how worms' noses sense oxygen
...ding fish. Humans may also have such a detector to trigger hyperventilation during exercise or exposure to anoxic environments. "We are immersed in a 21 percent oxygen atmosphere all the time, and our blood stream and lungs maintain the optimum oxygen levels in our tissues. So, we take oxygen levels for gra...Tracing a killer's path in Lou Gehrig's disease
...aggregation of the mutant protein with Bcl-2 could trigger the cell death machinery by either depleting Bcl-2 or even converting it into a cell death activator, concluded the researchers. The preferential aggregation of mutant SOD1 in spinal cord mitochondria "defines a potential Achilles' heel that may rend...Spanish scientists develop powerful tool for exploration and integration of biological information
...d Valencia expect this highly connected network to trigger a revolution in new text-mining tools that will bring biomedicine within closer reach of both the scientific community and the wider public....