4 October press briefing to focus on minority recruitment to science and engineering programs
...d Grutter and Gratz messages, issued in June 2003, triggered confusion among academic, non-profit, and federal institutions seeking to extend the benefits of education to all. Standing Our Ground features a "legal primer" to help guide university counsels in interpreting the Grutter and Gratz rulings. It also...Researchers ID chlorophyll-regulating gene
...because it binds to phytochrome, a protein that is triggered by light and that controls a plant's growth and development. The researchers disabled the PIF1 gene in the species Arabidopsis thaliana, a mustard plant, and compared the mutant seedlings with a control group of normal plants. They grew the see......ntil recently, scientists knew these diseases were triggered by a problem with mitochondrial fusion, but didn't understand fusion itself, says Jodi Nunnari, a UC Davis professor of molecular and cellular biology. Mitochondrial fusion was tricky to understand because mitochondria are structurally complex, Nunn...Disruption of protein-folding causes neurodegeneration, mental retardation
...osis. "No one knew that the UPR cascade could be triggered by GM1 accumulation in the ER," said Alessandra Tessitore, Ph.D., formerly a senior research technician at St. Jude. "This finding was unexpected and an important step in the search for an effective treatment for GM1 gangliosidosis." Tessitore is th...Wrapping a memory with an experience, capacity for recollection detected in non-human species
...ues have been used to distinguish memory responses triggered by familiarity, the general sense that a person or thing has been previously perceived, from those triggered by recollection, the sudden rush of detailed memory. The BU team chose to determine whether analyse......also involved in another apoptotic process -- that triggered by a receptor protein called TNF alpha, which also triggers the inflammation process. The researchers found that Compound 3 also switched on apoptosis in cells treated with TNF alpha. Thus, said Wang, Compound 3 might also be used as an anti-inflamma...Long-term effects of carbon monoxide poisoning are an autoimmune reaction
...otion an autoimmune response in which lymphocytes, triggered to eliminate altered MBP, continue to attack normal MBP. Specifically, the researchers found that by-products of CO metabolism in the brain alter the charge and structure of MBP. "These changes in MBP have also been demonstrated in multiple scleros...Molecular staples shape a cancer killer
... proteases. They also found that SAHB specifically triggered the cell's power plants, the mitochondria, to release a protein that participates in launching apoptotic destruction. Their experiments with leukemia cells cultured in the laboratory revealed that SAHB could enter, and, more importantly, inhibit the...Men from early middle ages were nearly as tall as modern people
...dramatically in the 1300s, when the Little Ice Age triggered a cooling trend that wreaked havoc on northern Europe for the following 400 to 500 years. Colder temperatures meant lower food production as well as greater use of resources for heating. But many temperature fluctuations, ranging in length from about...Brain's reward circuitry revealed in procrastinating primates
...Laboratory of Neuropsychology. "The gene knockdown triggered a remarkable transformation in the simian work ethic. Like many of us, monkeys normally slack off initially in working toward a distant goal. They work more efficiently make fewer errors as they get closer to being rewarded. But without the dopamin...Revealing bizarre deep-sea secrets
...ed scientists using other tools. The system can be triggered to begin recording at programmed intervals to record animals attracted to bait or to an artificial lure designed to mimic the light given off by a common deep-sea jellyfish. (For more information about Eye-in-the-Sea and the jellyfish lure, please se...Depression traced to overactive brain circuit
...nts nor tryptophan depletion in healthy volunteers triggered the mood and brain activity changes. Brain scans revealed that a key emotion-processing circuit was overactive only in patients in remission whether or not they had re-experienced symptoms and not in controls. Since the abnormal activity did not re...New discovery may help transplants survive
...enting cells. They also believed that VEGFR-3 then triggered the APCs to move into the lymphatic vessels en route to the lymph nodes to make contact with the T-cells. Using in-the-dish (in vitro) and living mice (in vivo), the team was able to show that VEGFR-3 was responsible for mobilizing APCs to move into...Misfiring proteins tied to inflammation and sick feeling of type 2 diabetics
...esistance, Freund said, is serine phosphorylation, triggered by hyperinsulinemia, of the insulin receptor substrates. This phosphorylation, Freund said, "impacts other signaling cascades in cells, controlled by cytokines, especially ones like interleukin 4, an anti-inflammatory protein." A connection to the cy...Good bacteria trigger proteins to protect the gut
...vidence that the infiltration of white blood cells triggered the increased injury in MyD88-deficient mice. The researchers observed a generalized disruption in proliferation and differentiation of intestinal epithelial cells in the MyD88-deficient mice, implicating TLRs in overall maintenance of the tissue. Th...New view of leukemia cells identifies best treatment options, Stanford researchers say
...s were able to avert the normal cell-death signals triggered by chemotherapy. Learning to recognize the pathways most commonly disrupted in aggressive cancers could help researchers predict which patients won't respond to standard chemotherapy. Doctors could immediately propose that the person consider le...How wounds heal Clues from flies
...y distinct genetic programs and signaling pathways triggered by the wound. Since many aspects of the fly wound response resemble those in mammals, it's likely that the molecular components are also shared. That makes identifying the molecular underpinnings of wound healing a high research priority. And thanks ......ashed through a complex chain of molecular events, triggered by master control proteins. These control proteins act as recruiting officers, rallying other proteins to set up the inflammatory defense. One of the most important molecular sergeants is a protein called nuclear factor-kappa B (NF-kB), which can ord...Skin condition linked to genetics in Caucasian and Chinese populations
...matory dermatosis, is believed to be inherited and triggered by environmental, as well as genetic, factors. It affects "2%-5% of the Caucasian population and 0.1%-0.3% in the far East and China." This new connection suggests that genes in Caucasians and this specific Chinese population may be involved in the......cular structure and also to confirm that it indeed triggered the hardening process. In the first phase of the work, the team went to work to determine the genetic sequence of bursicon. Using cockroaches, Honegger's students were able to collect and purify a small sample of the hormone. They sent this sample t...