Dendritic Cell Therapy For The Treatment Of Cancer
... somecancers. However, substances produced by the tumour prevent the cells fromdeveloping into a more matur...ies in culture. They can then be shownbits of the tumour to which the immune system will react (tumour antigens) andreinfused into the patient. A recent cli...Major Risk Factor For Cervical Cancer Found
... a key control point in the body's defence against tumour formation. Itprotects the genetic information in the cells from things which can damage themsuch as ultra violet radiation or certain chemicals. If p53 goes wrong then acell has a greater chance of becoming cancerous. Dr Alan Storey, leader of th...Persistent Organic Pollutants, The Danger Is Not Over
...stem, hormonal systems, the immune system and tumour formation", recommends the project group heading the research programme on persistent organic pollutants and which has advised the production of the Monitor 16 report. Briefs from Monitor 16: Reduced levels of to...The Body's Anticancer Weaponry Backfires In Old Age
...gher rates. Many cells in the body produce tumour necrosis factor (TNF), a proteinthat helps to destroy diseased cells by triggering the cell's self-destructmechanism. Most cells ignore the suicide instructions, and even switch onprotective mechanisms when exposed to TNF. But infected or cancerous c...The Origins Of Hereditary Breast Cancer -- Studies With Knock-Out Mice Reveal Underlying Mechanisms
...ne removed from the mammary glandcells developed a tumour within one year. The scientists noted that another...te some time, namely that the BRCA-1 gene acts asa tumour suppressor since it is involved in repairing damaged genetic material.Its loss of function causes a ...High fibre diet lowers risk of prostate cancer: study
...a reduction in the male sexhormones that stimulate tumour growth," says lead author Professor David Jenkins of the department of nutritionalsciences. "The hormones, which are produced from cholesterol, circulate through the body and a proportion of thesesteroids are excreted through the digestive process. S......ich no effective therapies have existed so far. As tumour cells form different types of receptors, specific ... them also in humans, e.g. for viral infections or tumour diseases. Dr. Dieter Willbold (34), Institute for Molecular Biotechnology, Jena Dieter Willbold inte...Cell division study aids cancer drug search
...le drugs which can arrest E2F activity and prevent tumour cell proliferation." This research contributes to a larger programme of work identifying targets for drug development being carried out by Prolifix Ltd, the UK-based cell cycle company. Professor La Thangue is chief scientific o...New liver cancer treatment; the current picture
... them. This process, termed electrolysis, destroys tumour and liver tissue in much the same way as electroly... of the 10 patients showed no evidence of residual tumour at the treatment site. 5 of these 8 patients had developed new areas of tumour spread, but 3 showed ......ervention. It may be possible in future to control tumour growth by using combinations of different target-b...ed at other times. The purpose would be to control tumour growth rather than destroying the number of tumour cells, shifting our overall aim from the often un...High hit rate in drug development
...s and also offer new promising starting points for tumour therapy (Angew. Chem. Ind. Et. 2002, in press). A ...ctron microscopic photographs of polymer beads and tumour cells. The tumour cells floating in front of the polymer beads were used in a cytotoxicity assay. Th...New test offers hope of easy and affordable screening for hereditary breast cancer genes
...tage of this test is that it can be carried out on tumour material stored from previous operations, which en...r the same loss was seen in the same place in both tumour samples. All genes and DNA material come in pairs, and when genetic material from one half of a pai...Scientists develop new drug to combat tamoxifen-resistant tumours
...t the activities of the oestrogen receptors on the tumour cells, while tamoxifen and raloxifene were only pa...d that TAS-108 and DeET-TAS-108 accumulated in the tumour tissue, thereby boosting the anti-cancer effect of TAS-108. Meanwhile Mr Yamaya carried out work to ...New study could cut overtreatment
... the pattern of gene expression in the tumour. The tumour tissue of the patients whose breast cancer had metatasised within five years had a different profile one in which the genes involved in the regulation of the cell cycle, cancer invasion, metastasis and angiogenesis (formation of blood vessels) were ...Candidate genes found which may play a role in cancer progressing from non-invasive to invasive
... actually responsible for suppressing or promoting tumour invasion. A few other laboratories are looking at ...patient care. If we do find genes responsible for tumour invasion, and if we can develop treatments to correct or prevent defects in them, then we have the c...Markers that can predict cancer spread could save women from unnecessary chemotherapy
...e of being cured of the disease by just having the tumour surgically removed without any follow-up therapy. ...metastasising, and found that markers for p53 (the tumour suppressor gene which is involved in many cancers), E-cadherin (the gene involved in making cells st...Scientists find groups of genes associated with different types and stages of breast cancer
...RNAs to identify which genes were related to known tumour and/or patient characteristics (such as whether the oestrogen receptor were positive or negative, tumour size and grade, lymph node involvement and menopausal status). They found patterns of gene activity ...Researchers identify gene for most common paediatric malignant brain tumour
...n medulloblastoma, the most common malignant brain tumour found in children. This research is reported in th...ther forms of cancer. Medulloblastoma, a malignant tumour that occurs in the cerebellum, accounts for 20 per cent of all paediatric brain tumours. It is a rap...Chips that analyse cancer genes
...Genetic material, DNA and RNA, is removed from the tumour and labelled. "This tissue sample is placed on th...all the characteristics that will show you how the tumour might behave. Thousands of genes can be tested simultaneously." Although scientists have a good dea...... it is possible to work out what might happen to a tumour before treatment has begun." Using DWMRI, the researchers were able to visualise and measure the water characteristics in the tissues of mice with colon carcinoma before and after chemotherapy. They found a significant correlation in the water diff...