Study in worms shows how genes linked to complexity in animals
...said. "Lin-48 itself is a transcription factor it turns on other genes that theoretically help C. elegans handle excessive levels of salt. But we don't know what other genes it affects. "Differences in gene expression contribute to structural and functional differences between species," she said. "In......Injection of amylin, or treatment with a drug that turns on the amylin pathway, might help correct the bone loss and osteoporosis seen in these diabetics. ...Jefferson researchers uncover biochemical clues to how cells migrate in embryos
...s into disease processes, including cancer. Cancer turns deadly when it spreads to other areas in the body. Dr. Farber and his co-workers report their findings in the February 2004 issue of the journal Developmental Cell. "We have identified an enzyme in zebrafish and there is a companion paper in th...Passwords to guard entry aren't enough to protect complex data
...rial authorized for his or her role. If a good guy turns bad - as in the case where a disgruntled employee with access privileges decides to do some damage - the database becomes endangered. A severe disadvantage to the access-driven security model is that it requires that all of the contents be well organ...New evidence points to pollution as main cause of much coral reef destruction
...nvironments," says Lapointe, "That finding kind of turns the whole field over." Lapointe says the group's results make it difficult to accept the view held by some coral biologists that reduction of grazers by overfishing is the main driving force behind the damaging spread of algae on reefs, a view known ...MIT student dances with robots
...llow seamless transitions between swing-outs, tuck turns and Texas Tommies. You might call this swing dancing. Or you might call it a highly evolved system of communication and control via haptic (touch-based) signaling. Graduate student Sommer Gentry, an expert swing dancer, sees it both ways. Gentry, who...Monkey talk, human speech share left-brain processing
...ey hears a call from behind, it characteristically turns its head to the right, suggesting that the primitive vocalizations are being processed in the left hemisphere, which receives greater input from the right ear than from the left. Also, a monkey's ability to perceive such calls is impaired if it lacks...Signal chemical primes plants for pest attack
... Science . Jasmonic acid is a plant hormone that turns on plant defenses, including VOCs, which are the chemicals that attract the caterpillar's parasites and predators. They usually do not appear until hours after the initial attack on the plant. "The GLVs appear to be like a vaccine, turning on the def...Predicting progression of common cancers
... cancer cells go through a fateful transition that turns them into fast-growing, invasive, metastasizing tumors first surfaced in the early 1970s. By the mid-1980s histological analysis revealed a similarity between the tumor "microenvironment" and that of a healing wound, prompting Harvard pathologist Har...Gene essential for development of normal brain connections resulting from sensory input discovered
...t example of a transcription factor-a protein that turns genes on and off-that appears to be specifically r...ilar between mice and humans," says Ghosh. "If it turns out that CREST plays a role in learning and memory in the mouse, then it is very likely it also play...UF study suggests life on Earth sprang from borax minerals
...r Miller's conditions." Ribose, like most sugars, turns into tar if not handled carefully. "It is like bak...und in Death Valley," he said. "Without it, ribose turns into a brown tar. With it, ribose and other sugars emerge as clean products." Benner then showed sim...Study by UCSD gives new insight into how anthrax bacteria can evade a host's immune response
...cade of proteins activating one another ultimately turns on cytokine genes, causing the macrophage to churn out large quantities of cytokines. It turns out that there are two separate, sometimes cooperating, routes in the cell by which series of protei...MIT helps unlock life-extending secrets of calorie restriction
...bolism leading to a slower rate of respiration, it turns out that respiration in yeast cells under calorie restriction goes up, not down. "A high respiration rate is intimately connected with calorie restriction in yeast," he said. "A high respiration rate activates SIR2. When respiration goes up, NADH goe...'Smart bomb' delivery destroys tumors in mice
...t encounters the alliinase, the resulting reaction turns the normally inert alliin molecules into lethal allicin molecules, which penetrate and kill the tumor cells. Due to the precise delivery system, neighboring, healthy cells remain intact. Using this method, the team succeeded in blocking the growth o...EGFR: A molecular lab rat let loose in systems biology
...ks or unlocks the desired reaction in the cell. It turns out that a strong and decisive snap of the bolts -...second ligand, so what's the difference?" Big, it turns out. If you swap domains, you alter the rates of secretions on the surface of the cell, and the cell...History of frog deformities suggests emerging disease
... culprit for many of the deformities in amphibians turns out to be the tiny parasitic worms, says Johnson, adding that both field and lab studies show that the more abundant the parasite, the more frequent and severe the malformations. Knowledge of this connection between parasites and deformities came i...Little-studied waves in the heart may be cause of defibrillation failure
... difficult to view and to study," Wikswo said. "It turns out cardiac tissue provides a beautiful example of these waves." Although cardiac graded responses have been considered for some time, recent advances in high-speed imaging, data processing and numerical modeling are just now allowing their quantitat...Expedition will retrace legendary Steinbeck-Ricketts voyage to the Sea of Cortez
...e it to the published version of the narrative. It turns out that Steinbeck keeps a lot of Ricketts' wording, and that huge chunks are simply cut and paste.'' A few months ago, Ed Ricketts Jr. provided Rodger a newly discovered typescript of his father's original notes, which include previously unpublished...Professor uses satellites to protect Amazon forests, global climate
...his felled wood becomes harvested timber; the rest turns to waste. Selective logging dominates current landscape use in Brazil and is also among the biggest threats to the global environment. At the same time, people involved in the timbering process - clearing land and removing wood with tractors - furthe......nes were imprinted in humans," Piedrahita said. It turns out that Piedrahita's group discovered two new imprinted genes that have never been reported before. The implications are far reaching. "What all of this is telling us is that the mechanisms that are dis-regulating genes in the pigs can be translate...