Tag: "ulcerative" at biology news

University Of Chicago, Hopkins Narrow Search For Inflammatory Bowel Disease Genes: New Study Provides Evidence For Important Gene-Gene Interaction

...bowel disease (IBD)--including Crohn's disease and ulcerative colitis--hasfocused and narrowed the search for th...ry bowel disease includes Crohn's disease (CD) and ulcerative colitis(UC), chronic disorders that primarily affect the intestines, causing pain,severe diarrhea, i...

New Evidence For Growth Factor Role In Crohns Disease

...activity in bowel tissue from surgery patientswith ulcerative colitis, the second major inflammatory bowel disorder, one thatinvolves only the colon. Lund says the bowel in some CD patients "tries to overgrow, something goes wrongand the structural support elements of the tissue grow excessively, and so youget ...

A few gut parasites could do you the world of good

... Inflammatory bowel disease-an umbrella term for ulcerative colitis andCrohn's disease-appears to be caused by an overactive immune system. Symptomsinclude diarrhoea, abdominal pain, bowel obstruction and bleeding. Weinstock noticed that the rise in inflammatory bowel disease waspreceded by a decline ...

Vitamin D deficiency and bowel diseases connected

...ciency worsens the symptoms of Chron's disease and ulcerative colitis. Treatment with Vitamin D for as little a... develop the symptoms of either Chron's disease or ulcerative colitis were also made vitamin D deficient at birth. The mice were then either maintained deficient...

Little-known substance regulates inflammatory response

...gs designed to treat inflammatory diseases such as ulcerative colitis, Crohn's disease, rheumatoid arthritis and...proval for treating inflammatory disorders such as ulcerative colitis, Crohn's disease and arthritis. However, "these therapies are not always effective," said ...

Researchers identify 170 genes involved in Crohn's disease and ulcerative colitis

... the first genetic profile for Crohn's disease and ulcerative colitis, two types of inflammatory bowel diseases ... individuals who had Crohn's disease (CD), 12 with ulcerative colitis (UC), and six unaffected controls. The scientists screened 7,306 human genes, searching for ...

Hormonal changes during physiological development can alter immune response to viruses and infections

...em, such as systemic lupus erythematosus, diabetes ulcerative colitis, and arthritis. Why men and women respond differently to infections caused by viruses or other parasites remains a mystery. How the immune system adopts certain strategies towards particular illnesses has not been determined. Examining ge...

Enzyme mimetic reduces tissue damage in colitis animal study

...matory bowel disease, including Crohns disease and ulcerative colitis, said Daniela Salvemini, Ph.D., MetaPhores Vice President of Pharmacology and the principal investigator. The protective effects observed in this model appear to be a result of the SOD mimetics ability to inhibit superoxide and cytokine pro...

Cancer-fighting drug may work in prevention and treatment

...f America, Clapper has focused on individuals with ulcerative colitis, which increases the risk of colon or rectal cancer by 10 times. In studies with laboratory mice, Oltipraz has proved to inhibit colitis-associated colon cancer. This research will form a basis for designing the first trial of a preventive ...

Control of intestinal inflammation by PGE2 and its receptor

...gastrotoxicity and might also prove beneficial for ulcerative colitis and Crohn disease, conditions where the gastric mucosa is prone to inflammation and tissue damage....

Stressed intestine can give rise to food allergy

...ious intestinal diseases, such as Crohn's disease, ulcerative colitus and irritable bowel syndrome can in part be caused or enhanced by chronic stress. The mechanism behind this has yet to be elucidated....

Univ of MD study on prevalence of celiac disease

...ase, making it twice as common as Crohn's disease, ulcerative colitis and cystic fibrosis combined," says Alessio Fasano, M.D., the study's principal investigator and professor of pediatrics, medicine and physiology at the University of Maryland School of Medicine. Celiac disease is a digestive disorder that ...

Study shows ulcerative colitis patients achieve remission with probiotic composition VSL#3

...6 percent in patients with active mild to moderate ulcerative colitis who were not responding to conventional th...Week (DDW) meeting. Affecting 500,000 Americans, ulcerative colitis (UC) is a form of inflammatory bowel disease that causes the gastrointestinal tract to becom...

Curcumin may be an inexpensive, well-tolerated, and effective therapy for inflammatory bowel disease

... bowel disease (IBD) refers to Crohn's disease and ulcerative colitis, debilitating illnesses characterized by chronic recurrent ulceration of the bowel, abdominal pain, digestive problems, diarrhea or constipation. The National Institutes of Health estimates that some two million Americans suffer from this di...

Critical Therapeutics announces issuance of US patent for novel anti-inflammatory technology

...ses such as rheumatoid arthritis, Crohn's disease, ulcerative colitis and sepsis. Patent No. 6,610,713 stems from research conducted by the inventor - CTI co-founder Kevin J. Tracey, M.D. - and his colleagues at North Shore-Long Island Jewish Research Institute's Laboratory of Biomedical Research. CTI in-licen...

Celiac disease is a risk factor for schizophrenia

...uded dermatitis herpetiformis, Crohn's disease and ulcerative colitis.The researchers found a small number of sc...h a history of celiac disease. Crohn's disease and ulcerative colitis were not associated with an increased risk of schizophrenia. "More research is needed to u...

U of T researchers isolate gene for Crohn's disease

...physicians distinguish between Crohn's disease and ulcerative colitis, the other major form of inflammatory bowe...l disease known. The malfunction is not present in ulcerative colitis, so this gene alteration provides a diagnostic test to help distinguish between the two dise...

Flagellation in Crohn disease

...rols and from patients suffering from another IBD, ulcerative colitis, were nonreactive. These findings underscore the link between the innate immune response and the pathogenesis of IBD and offer leads to the identification of other causal antigens in CD....

JCI table of contents, 17 May 2004

...uce IL-13 characterize an atypical Th2 response in ulcerative colitis AUTHOR CONTACT: Ivan J. Fuss, National Institutes of Health, Bethesda, Maryland, USA. Phone: 301-496-6810; Fax: 301-402-2240; E-mail: ifuss@niaid.nih.gov View the PDF of this article at: https://www.the-jci.org/press/19836.pdf * Idiosyn...

JCI Table of Contents, 15 July 2004

...e properties of apoA-IV in a mouse model for human ulcerative colitis. By feeding mice with a heparin-like poly... colitis that has several characteristics of human ulcerative colitis. In experiments examining DSS-induced colitis in mice that were given exogenous apoA-IV and...

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