Tag: "unable" at biology news
Nerac.com and Infinata partner to offer BioPharm Insight(TM) Resource
...ide data that both our Specialists and clients are unable
to find through other resources," said Nerac's President Kevin Bouley. With access to the BioPharm Insight resource, Nerac's Information Specialists will be able to search for drug development activities that include recently approved drugs, drugs wi...
Academic clinical research is under threat from the EU
... death or years of suffering because they would be unable
to benefit from new and better treatments for their cancers. The discovery of a new and effective treatment for a rare and difficult-to-treat cancer has highlighted the way international collaboration can be translated into benefits for patients in a...
Researchers solve the mystery of a key structure in immune system cells
...ng T-cell receptors. The modified mice were indeed unable
to form a well-organized immunological synapse, or...o strong antigen signals. But Dr. Shaw's study was unable
to show exactly why the defective T-cells weren't functioning correctly. To decisively prove the con...
SPR Annual Meeting features newsworthy discoveries
...heir bodies, a nightmarish state in which they are unable
to control so much as an eye blink and, until recently, making it nearly impossible to communicate their thoughts or needs. The Thought-Translation-Device (TDD) uses a web-accessible computer platform allowing patients to communicate directly with a ...
Old drug works new tricks for iron overload heart disease
...on are causing damage to those who are genetically unable
to adequately metabolize and excrete it. Other researchers on this paper are Hui Sun, Maria Trivieri, Fayez Dawood and Mehrdad Yazdanpanah of the Heart & Stroke/Richard Lewar Centre of Excellence and the Departments of Medicine and Physiology at U of...
Watching social behaviour evolve
...anthus genome. The resulting non-social mutant was unable
to swarm effectively on soft agar and was used to ...s of the evolved strains were constructed that are unable
to make fibrils and are therefore do not swarm. The swarming defects of these mutants, however, coul...
JCI Table of Contents
...th gonadotropins. The exogenous gonadotropins were unable
to drive follicle development to the preovulatory stage in the presence of antiVEGFR-2 antibodies. These results show that the intraovarian VEGF/VEGFR-2 pathway is critical for gonadotropin-dependent angiogenesis and follicular development. TITLE: Va...
Leishmania mutant provides insight into disease and may lead to a vaccine
...nt they were completely eliminated. They also were unable
to survive in macrophages. Next, the investigators injected the parasites into mice that were genetically susceptible to leishmaniasis. As expected, the animals did not become sick, suggesting that the parasites had not survived. Surprisingly, thoug...
Scientists identify new sperm protein required for fertilization
...xamined in the laboratory, sperm without SED1 were unable
to bind to an egg. Further, mice without SED1 had greatly reduced fertility even though the sperm appeared normal in number and motility. These results strongly suggest that SED1 plays a critical role in the initial association between sperm and ...
How AIDS destroys immunity
... other methods to block the ATR gene and render it unable
to help the AIDS virus vpr gene stop cells from re...three cases, interfering with the ATR gene left it unable
to help the AIDS virus' vpr gene. As a result, the cells in the experiment were able to replicate. T...
Researchers find a pattern in evolution of lizard groups
...ory suggests that ecologically similar species are unable
to coexist through long periods of time in the same geographic area. If lineages with different ecological adaptations arose early in the history of a group, their descendants could coexist geographically through long periods of evolutionary time by ...
Respiratory manifestations may be secondary to inflammation in cystic fibrosis patients
...n by blood neutrophils, dexamethasone (10 6 M) was unable
to repress secretion of IL-8 by airway neutrophils. In addition, comparison of cytokine production by airway neutrophils from children with CF and children with dyskinetic cilia syndrome also documented distinct profiles of secretion. Conclusion...
Fears of second-hand smoke confirmed
...ss of elasticity). At that point, the air sacs are unable
to completely deflate and are therefore unable
to fill with fresh air for adequate ventilation. Two of every 1,000 Americans develop this disease...
Protein that fights bacteria and viruses cloned by Scripps scientists
...tation in a mouse gene that made mouse macrophages unable
to sense certain pathogens, thus weakening their i...irus," says Beutler, adding that the mice are also unable
to respond to bacterial endotoxins, like lipopolysaccharide (LPS) molecules, which are found in the ...
Wildland fire impact on watersheds: A special conference of the Geological Society of America
...( firstname.lastname@example.org ). Writers interested but unable
to attend should contact Ann Cairns for assistance. Partial funding for this conference is provided by the U.S. Geological Survey Joint Fire Science Program, the U.S. Environmental Protection Agency, and the Colorado Department of Public Health and E...
Emory researchers discover novel mechanism of how anthrax impairs immunity
...equently, the dendritic cells become lethargic and unable
to act normally, thereby preventing the activation...anthrax lethal factor, the innate immune system is unable
to stimulate the immune response, thus permitting the microbe to spread unchecked. Our ultimate goal...
Penn researchers identify secondary pathway for survival of cancer cells
...functioning inside the cell), were cancerous cells unable
to survive and died. The Akt pathway is well studied because it plays many roles in cancer progression, including a key role in cancer cell survival. Both Pim-2 and Akt survival pathways were found to operate independently; Pim-2 was not activated...
Study results show promise for development of gene therapy to treat blood diseases
...o the donor red blood cells. "Currently, we are unable
to transplant an adequate number of genetically al...e able to carry sufficient oxygen. If the body is unable
to produce adequate amounts, the result will be anemia that begins in early childhood and lasts thro...
Abnormal plant shows scientists path to plant, animal development
...The mutated gene, designated as lowercase pkl, was unable
to repress the embryogenesis genes. The result is a plant that is dwarfed compared to a normal plant, has a pickle-shaped root, and characteristics of both an embryo and an adult plant. Ogas said they found that embryo-promoting genes are expressed a...
Scientists uncover amyloid-like proteins in bacteria
...streptomycetes lacking specific chaplin genes were unable
to erect aerial hyphae, but that this condition could be restored through the application of exogenous chaplin proteins. The authors suggest that coating of the aerial hyphae by chaplin proteins may confer hydrophobicity to these structures, allowi...
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