Tag: "uncontrolled" at biology news

Blocking the binge: UF researchers explore for uncontrolled eating

...of binge eatingepisodes, with four patients ending uncontrolled consumption completely, saidDr. Nathan Shapira, an assistant professor of psychiatry at UF's College ofMedicine. Shapira, who led the research effort while on the faculty of the University ofCincinnati, presented the findings today in a poster sessio...

Enzyme discovery may link underlying processes in cancer and heart disease

...ovasculardisease. In the case of cancer, rapid and uncontrolled cell division leads to tumorformation. In cardiovascular disease, abnormal cell growth leads to theformation of plaques seen in hardening of the arteries (atherosclerosis) and inthickening of the blood vessel walls, which causes high blood pressure....

Enzyme inhibitor reduces cardiac cell death in heart attack

...inates damagedor diseased cells. However, uncontrolled apoptosis causes many human illnesses, includingheart disease, cancer, neurodegenerative diseases and autoimmune disorders. Cryns' research is aimed at understanding and describing the apoptoticpathways -- the crucial steps that activate the ...

Mutation in PTEN gene can cause cancer and autoimmune disease

...o interrupt cell signaling andbegin the process of uncontrolled cell growth." Mutations of the PTEN gene are found in a large number of human tumors. Theseinclude cancers of the breast, prostate, endometrium, ovary, and colon, as wellas melanoma, glioblastoma. and lymphoma. The inherited inactivation of one copy ...

'Frozen pictures' allow far-reaching glimpse into the cells protein factory

...e day improve the ability to fight the pathogenic, uncontrolled protein production characteristic of cancer cells. Prof. Ada Yonath holds the Martin S. Kimmel Professorial Chair. This research was funded by the Max Planck Society, the US National Institute of Health, the German Federal Ministry for Education an...

'Cell junctions' respond to environmental signals

...tions. Mutations in tumor suppressor genes lead to uncontrolled cell growth and, consequently, tumor formation. Genes that are first discovered in fruit flies often lead the way to way to important advances in our understanding of human diseases, including cancer. Another presentation will focus on how a cancer...

Awareness, quick action key to battling canine bacterial disease

...e vomiting may occur. The dog also may have rapid, uncontrolled fine muscle twitches." Fenwick said a consistent a...ions. At an early stage vomiting may occur. Rapid, uncontrolled fine muscle fasciculations are often noted. A consistent and important clinical finding is a very hi...

Non-toxic peptide blocks spread of prostate cancer in rats

...nt added. "But we believe aberrantly regulated or uncontrolled cell migration will prove to be equally important. There appears to be a biochemical 'on switch' controlling tumor cell movement, which may be activated by the defective receptor pattern of key receptors on cancer cells. Our goal is to learn how to...

International trade imperils U.S. plants, animals and crops

...e than 100,000 different seeds are involved in the uncontrolled seed trade today, with at least 59,000 species available in U.S. seed catalogs alone, she said. In addition, many species introduced as ornamentals have become highly invasive and ecologically damaging plants. These range from kudzu and the tree me...

Study stopped early: high blood pressure drug less effective than diuretic

... heart attacks, strokes and other complications of uncontrolled hypertension. The approximately 9,000 study participants who took Cardura had 25 percent more serious complications from hypertension than the group taking the diuretic chlorthalidone. The participants in the Cardura group were also twice as likely...

Magnetic fields may hold key to malaria treatment, UW researchers find

...s what causes malaria's hallmark symptoms: fever, uncontrolled shivering, aches in the joints and headaches. Infected blood cells can block blood vessels to the brain, causing seizures and death. Other vital organs are also at risk. Lai's research appears to take advantage of how the parasites feed. Malaria ...

UC Berkeley biologist disputes current dogma that genetic mutation is the cause of cancer

... of genetic mutations that drive a cell into wild, uncontrolled growth. Molecular biologist Peter Duesberg, better known for his claim that the human immunodeficiency virus is not the cause of AIDS, contends that mutation is not the cause of cancer. Rather, he says, cancer results from disruption of the normal nu...

White House honors Hutchinson Center Scientist with Presidential Early Career Award

...d, are the same ones that later mutate and produce uncontrolled cell growth in cancer. "Development is a process that includes cell differentiation, cell growth, cell division and cell death - many of the same processes that are going wrong during cancer growth," she says. "So it stands to reason that many of the...

Protein found in yeast and humans appears to play a key role in regulating cell growth

...s protein may be a very sensitive indicator of the uncontrolled cell growth characteristic of cancer," says Reeder, also an affiliate professor of zoology at the University of Washington. Because of its potential commercial applications, Reeder and colleagues have filed a patent application on the gene that produ...

Two NHLBI studies confirm finding of gene in primary pulmonary hypertension

...re." PPH is a rare lung disease characterized by uncontrolled proliferation of cells in the blood vessels in the lungs. This build-up of cells leads to blockages in the blood vessels, forcing the heart to pump harder and increasing blood pressure in the pulmonary artery. The disease affects twice as many wome...

Chemists report new approach to synthetic fragments of medically important Heparin

...re Heparin fragments could be used to turn off the uncontrolled cell growth that causes cancer. While the actual medical use of novel Heparin fragments is still some years away, the matching of the fragments to proteins is much nearer. "We believe that in two years, we will be able to test larger fragments on p...

Scientists develop chemical switch for natural signaling molecules, opening new approach to biomedical research and drug design

...ning overactive enzyme activity often involved in uncontrolled tumor growth, Shokat says. Shokat is confident that mutant kinases in animals will prove useful for screening such drugs. "In our experiments, we essentially identify potential drugs to inhibit kinases as we are proceeding in our basic research...

UCSF-led study offers insight into cancer development, resistance to therapy: finding focuses on Ras oncogene

... certain critical genes that nudge a cell into the uncontrolled growth that is the hallmark of cancer. The Ras oncogene's ability to suppress p53 could explain, says co-lead author Carola Biederer, PhD, a postdoctoral fellow in McCormick's lab, why some cancers are resistant to radiation therapy. Irradiation dama...

Yale scientists give the Golgi apparatus its own identity, paving the way for more targeted cancer research

...vision process and of the processes present in the uncontrolled cell division that marks cancer. In normal cell division, a mother cell divides into two daughters and the division is regulated until it stops. In a skin melanoma, for example, the cell division inexplicably starts up again and continues unregulate...

Millennium's LDP(PS)-341 inhibits growth and induces death of cancer cells, appears to overcome chemotherapy resistance

... the immune system's plasma cells undergo abnormal uncontrolled growth and reproduction. Multiple myeloma cells prevent the marrow from forming normal plasma cells and other white blood cells important to the immune system. Patients with multiple myeloma may not be able to fight infection and disease and often ...

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