Heart size and function uncoupled by researchers
...es in heart size and function and have genetically uncoupled them, a discovery the scientists hope will lead to better treatments for those with cardiovascular disease. "We initially had a hint that the protein called PTEN controls cell size," says Josef Penninger, professor of medical biophysics and immunolog...Oxidative damage to eNOS by tissue peroxynitrite
...f recombinant eNOS, the combination of coupled and uncoupled catalysis generates NO and superoxide, and therefo... homodimer, leaving an enzyme that operates in the uncoupled mode. The structural change thus favors the production of more superoxide and peroxynitrite, which c...MCG researchers study hormone that may prevent bone being lost in space
...n bone. The balance of bone loss and production is uncoupled by weightlessness and by hormonal loss that occurs with age, Dr. Isales said. "You can break down bone, but you don't form it as well," without the natural force of gravity. Bone loss and production are constants in life, with the average person refo...Brain neurochemicals, not gender, tell a female to act like a female
...gonadal sex and social/reproductive tactics may be uncoupled from each other and regulated independently within the same brain region." Goodson adds, "Apparently, the process of evolution has modified reproductive and social behavior independent of the gonads. This blending of characteristics should make mo...