New signaling pathway found, may be linked to movement disorders
...GF14 does at the molecular level, I believe we may uncover a new mechanism for regulating nerve cell function." The work is published in the July 3 issue of the journal Neuron. It is the first study to examine the role of FGF14 in living animals and could provide new targets for testing future drugs designed...Emory School of Medicine teams with deCODE Genetics to study link between genes and disease
... for conducting population-wide linkage studies to uncover the genetic factors involved in common diseases. ...tudies within Emory's diverse group of patients to uncover the full range of mutations or versions of these genes that might predispose individuals to disease....Unraveling the genetics behind melanoma and colon cancer
...ing and tumorigenesis is less well established. To uncover novel genes that are activated in response to b- and g-catenin expression, Dr. Ben-Ze'ev and colleagues preformed a DNA microarray analysis of human renal carcinoma cells expressing b-catenin and/or g-catenin. Of 10,000 genes analyzed, Nr-CAM was the...LSU part of national Tree of Life effort
... NSF Tree of Life Project is an enormous effort to uncover the evolutionary history and characteristics of all groups of organisms. Over the next 10-15 years, a modern scientific view of the evolutionary tree that unites all organisms on Earth will be assembled and made available on the Internet. The LSU Mu...Laboratory study explains clinical promise of anti-angiogenesis cancer drug
...990s, research at the U-M and elsewhere started to uncover the role of copper in angiogenesis -- both the normal process that goes on constantly in the body, and the uncontrolled angiogenesis seen in cancer. Researchers found that copper was important to various "growth factors" that are necessary to the org...Heart disease gene linked to prostate cancer
... and colleagues will conduct additional studies to uncover the pathway that the MSR1 gene controls and confirm the prevalence of MSR1 mutations in larger studies....UCLA science profs awarded $1 million Howard Hughes Medical Institute grants
...l use state-of-the-science genomic technologies to uncover significant genes. The course will teach students how to think critically about experimental science and societal issues raised by emerging new genetic technologies. "Students will emerge from the course with a conceptual background in what genes are...Newly revealed viral structure suggests a continuum in the evolution of viruses
...e has combined two different imaging techniques to uncover the molecular-level framework of a common bacteriophage, a virus that infects bacteria. The results, reported in the October issue of Nature Structural Biology, suggest that viruses developed a continuum of progressively more complex architectural s...Mosquito genome sequence--Published in the journal Science
...number of sequenced genomes grows, scientists will uncover more information about the behavior, development, evolution, and often complex and highly adapted body plans of insects. Researchers have identified different molecular and chromosomal forms within the A. gambiae species. These forms may occupy di...Tourists, soothsayers & scientists try to predict peak Fall foliage color
... color, but it will take years of further study to uncover the many mysteries of autumnal color displays. Scientists do know that cold temperatures and less daylight trigger the breakdown of green chlorophyll from leaves to reveal the yellow that exist hidden beneath all summer. "Then the leaves can also pro...Study to determine if infidelity among birds an attempt to avoid inbreeding, diversify genes
...understand. Another mystery scientists have yet to uncover is what are the consequences of inbreeding? "We don't have a good measure of what would have been the fertility of the eggs or the growth and survival of the chicks after hatching if she had not selected a mate other than her partner," Sandercock sai...JGI to decode DNA of destructive plant pathogen
...e two Phytophthora genomes, the scientists hope to uncover clues to virulent diseases that are attacking 17 species of trees on the West Coast, including redwoods, big leaf maples, bay trees and Douglas fir, and causing serious damage to soybean crops in the Midwest and South. "This is an ideal opportunity f...Families with two or more children with autism sought for $10.2 million study
... a $10.2 million University of Washington study to uncover the genetic and neurobiological causes of autism. The National Institute of Child Health and Human Development, one of the National Institutes of Health, is funding the study, which is also designed to develop intervention programs to assist child...Experimental 'gene switch' increases lifespan with no ill effects
...s are having their cake and eating it too." "As we uncover more about how these and related genes function we hope to learn how youthfulness and longevity can be extended in humans without any side effects as well." Kenyon made international news in 1993 when she discovered that blocking daf-2 activity in C....Field Museum plays key role in massive project to map Tree of Life
...hylogeny ($2 million) This project will attempt to uncover the evolutionary patterns among archosaurs, focusing on theropods. Archosaurs vary tremendously, from marine crocodiles to bipedal, flying birds. "They're arguably the most dominant group of terrestrial vertebrates from the Triassic to the present an...UCSD bioengineers develop first computer model that predicts disease variant based on genetic defect
... scientists are feverishly developing processes to uncover SNPs that are related to variations of diseases such as cancer, heart disease and a host of inherited disorders. Until now, most approaches have relied on statistical correlations between reported mutations and occurrences of disease variants. Pals...UT Southwestern scientist helps identify gene that may lead to treatments for sleep disorders
...T Southwestern Medical Center at Dallas has helped uncover key information in the treatment of sleep disorder...t flies have long been used as a model organism to uncover the molecular basis of the circadian clock. Researchers isolated the first identified clock gene, pe...Researchers find genes connected to seasonal reproductive clock in hamsters
... some animals, this study is unique in helping uncover at least part of the genetic basis for determining how the reproductive system shuts off in the fall and restarts in time for spring. "This study offers some of the ...Search for cholesterol absorption genes narrows to two chromosome regions
...ere to look, we can use a variety of techniques to uncover their identities." Cholesterol: good and bad Cholesterol is an essentially fatty molecule found in blood and in all body cells. But, when too much of it floats throughout the blood, this waxy substance can clog arteries that feed the heart and brain,......egion on a specific chromosome (chromosome15) . To uncover the gene in that region, they then turned to Profs. Doron Lancet and Jacques S. Beckmann of the Crown Human Genome Center at the Weizmann Institute's Molecular Genetics Department. Both teams, after four years of intensive research, discovered and ch...