Tag: "uncover" at biology news

JCI table of contents, March 1 2004

...************************************* Researchers uncover physiological significance of two proteins, I kappa B alpha and I kappa B beta, previously thought to possess redundant properties in liver injury The NF-kappa B family of proteins orchestrates cellular responses to injury by regulating immune funct...

USC researchers link unusual DNA structure to cancer

...lleagues had previously used similar techniques to uncover the first new, stable structure in DNA, which was associated with an antibody-production process called class switching. This structure, however, looks different from the previous structure found, and is further distinguished by being associated with...

Nerac rebuilds TOC Journal Watch service with new search engine

...e the online system is so easy to use, clients may uncover journals they didn't even know existed," said Kevin Bouley, Nerac President. With coverage provided by the British Library, one of the world's leading resources for publications data, clients can search nearly 100 subcategories in the areas of Agricu...

The biological clock: What really makes us tick

... main reasons for studying circadian rhythms is to uncover the impact they have on human health and well bein... to various types of depression and may ultimately uncover ways to better cope with shift work and jet lag. Hardin's enthusiasm for this burgeoning field is ...

Carnegie Mellon U. conducts first comprehensive proteomic analysis of developing animal

..., together with other experimental tools, can help uncover the network of functions and interactions required for a variety of developmental processes and disease states." Minden said....

Molecular midwives hold clues to the origin of life

...stry journal Angewandte Chemie. "We are working to uncover how molecules similar to RNA and DNA first appeared on Earth around 4 billion years ago. Our theory is that small, simple molecules acted as templates for the production of the first RNA-like molecules. Many of these small molecules, or molecular mid...

Researchers caution against linking strep, neuropsychiatric disorders

...tions and behavioral difficulties in an attempt to uncover any link between the two. Every three months the children receive a physical exam, including a blood test, regardless of how they feel, since children with strep often feel fine. In addition, nurses obtain throat cultures from the children every mont...

Researchers identify unifying code among diverse classes of natural antibiotics

...tional methods to analyze molecular databases and uncover complex structure-function codes that would otherw...all secondary structures. These approaches did not uncover more comprehensive structural motifs that are conserved among diverse classes of antimicrobial pepti...

Nerac.com to deliver newswire feed twice daily

...feeds from international sources will help clients uncover today's global information before it becomes yesterday's news. "Through Newspaper Abstracts, ProQuest always delivered a top-notch product. Now with Newswire Feed, Nerac can offer a custom-built resource for our clients that is business targeted and...

Many scientists believe the dog genome holds information that will benefit human health

...tanding these genetic relationships will help them uncover the genes responsible for the physical features and behaviors unique to each breed as well as the diseases to which they are commonly susceptible, such as cancer, deafness, blindness, heart disease and hip dysplasia. The findings also have generated ...

Cell growth and death controlled by single pathway in lymphoma cancer model

... This fusion protein offered researchers a way "to uncover the relationship between two major pathways involved in cancer development," says Stoffel. The researchers first discovered the fusion protein acts like an oncogene, or cancer-causing gene, that can promote unrestricted cell growth. To identify the ...

Virginia Bioinformatics Institute researcher advances fight against sudden oak death disease

...s better understand P. ramorum's genome makeup and uncover valuable information to help cure and prevent sudden oak death disease. In addition, the sequencing of the P. ramorum genome represents the fastest tracking time between the identification of a complex pathogen (in 2000) and the completion of its gen...

UNC scientists uncover crucial mechanism for blood vessel development

...1 are poorly understood and have been difficult to uncover until now, said Bautch. Research by Bautch's group reveals for the first time that flt-1 positively controls sprouting by regulating endothelial cell migration. UNC co-authors postdoctoral researcher Joseph Kearney and graduate student Nicholas Kappa...

Monkey business: Studies show tiny callimicos have unusual characteristics

Sometimes it takes time to uncover nature's secrets. Take the case of callimicos, also called Goeldi's monkeys, a reclusive and diminutive South American primate. Discovered a century ago by Swiss naturalist Emil August Goeldi, the animals were once considered to be a possible "missi...

A protein's role in progressive renal disease

...erited forms of FSGS as probes, scientists hope to uncover the mechanisms that unleash the disease and to find ways to stem the damage. Mutations in the ACTN4 gene, which encodes a protein called a-actinin-4, cause an inherited form of FSGS. The protein normally remodels actin filaments, the primary structu...

Lupus Research Institute awards $3 million in novel research grants to further new science in lupus

...ation and cell death. In addition, this work will uncover whether HMGB1 can be a target of therapy. Luminita Pricop, MD, Hospital for Special Surgery, New York GENETIC AND ACQUIRED MODIFIERS OF APC FUNCTION IN SLE. Dr. Pricop's extremely novel research concept focuses on the role of inhibitory Fc rec...

Flies may taste bitter better, first map of insect 'tongue' reveals

...tion of the remaining Gr receptors. As researchers uncover the key molecular components underlying insects' senses of taste and smell, the findings might be applied to the development of improved insect repellants, Amrein said. For example, compounds that specifically block proteins underlying insects' feedi...

Argonne scientists determine structure of staph, anthrax enzyme

...eral months. By analyzing genomes, the researchers uncover information that will lead to structure-based or "rational" drug design. The problem is that researchers don't know what half the proteins coded by the genome do or how they work. Now that the researchers understand the enzyme, they hope to find a wa...

Genetic model for devastating form of paraplegia suggests new treatments

... "It may seem surprising that a fly can be used to uncover the molecular basis of human disease, but it has been shown over and over again in the last several decades that insights gained from Drosophila studies provide immediate insight into the human condition. There is a long history of Drosophila researc...

Scientists describe the world's smallest, lightest fish

... by researchers at Scripps and around the world to uncover new information about the animal world. "Collections such as these provide an enormous library of materials that allow us to make comparisons for new discoveries," said Hastings. "Unless you know what's already known, you don't know what's new."...

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