Punching the timeclock of life
... "We're also not saying that humans are, for sure, undergoing programmed aging. But, most likely, most organisms undergo programmed longevity. Life is programmed. Whether death is programmed or not is yet to be determined." ...Knock knock knocking on rhythm's neural doors
...ts, who performed a simple flex of the wrist while undergoing fMRI monitoring. A visual signal instructed the subjects to do one of three actions: rhythm -- flexing the wrist repeatedly at a comfortable pace, back and forth; discrete -- flexing the wrist, pausing, flexing it back, and rest. Another set of exp...European common frog found to use novel mating strategy
...le of such a complex mating behavior in amphibians undergoing external fertilization," Vieites said. "Because of a population excess of males, the males found a system to reproduce without the female." He and colleagues in Spain, Germany and The Netherlands report their findings in the Sept. 16 issue of Nature...Can an old gene learn new tricks?
...ven a new purpose through 'reassignment' to organs undergoing evolutionary advancement. The reassignment likely comes through a shuffling of existing regulatory elements to generate new combinations that are specific to the new organ," explains Dr. Lufkin.......vely active Cdc42 prevented mesenchymal cells from undergoing their normal epithelialization, while interference with Cdc42 function by a specific inhibitor caused an unusually high number of the mesenchymal cells to take on epithelial characteristics, demonstrating the central role of this GTPase in somitogeni...Fossils reveal direct link between global warming and genetic diversity in wildlife
...ty during the time that their population sizes are undergoing reduction. Pocket gophers, on the other hand, are subterranean rodents. They dig underground burrows that are very energetically expensive to build, and they kind of stick in one place." Subtle message These results have important implications for ...Skin stem cells give hairless mice hair
...r question was whether these cells were capable of undergoing self-renewal. And of particular interest to clinicians was whether they could undergo division in a lab dish and still have the capability to perform either epidermal repair or hair-follicle generation." To answer those questions, Fuchs and her coll...JCI table of contents: 1 September, 2004
...locked damaged cells in the young lung tissue from undergoing programmed cell death. The authors used inhibitory antibodies to further show that the protein p50, a part of the NF-kB complex, is necessary for protection from hyperoxic damage. They then created a mouse that lacked the p50 protein, and found that ...Other highlights in the September 1 JNCI
...e the optimal dose of interferon alfa for patients undergoing immunotherapy. Contact: Michelle Gailiun, Ohio State University, 614-293-3737, gailiun-1@medctr.osu.edu Scientists Outline Best Methods for Determining Health Benefits of Diet and Exercise Changes in patterns of diet and exercise are need...Washington University in St. Louis plays key role in sequencing moss genome
... simple cell and tissue types, ease in growing and undergoing sophisticated genetic manipulation including the capacity of this organism to integrate transforming DNA by homologous recombination at frequencies higher than that of any other multicellular eukaryote. This feature provides a unique tool for sophist...When is a mouse like a test tube?
...ers an alternative way to visualize cells that are undergoing a change in metabolism, such as happens with cancer cells and inflamed cells that over-produce sialic acid. The technique opens the door to non-invasive imaging of sugars as markers of disease." "Irrespective of its biological relevance, the method i...Rutgers-Newark scientist: Mosquitoes may carry lethal parasite
...s, organ-transplant recipients and cancer patients undergoing chemotherapy who have a low white blood-cell count need to take extra care to avoid ingesting microsporidial parasites. She recommends that they always boil tap water before consuming it or stick to bottled water as long as the source of the bottl...UC Riverside researcher takes snapshots of the movement of molecules in a billionth of a second
...individual site-to-site displacements of molecules undergoing ultra-fast dynamics induced by femtosecond laser pulses," Bartels said, characterizing the technique as a way of getting something akin to snapshots of the molecules' movements. Bartels' co-authors in the paper included Tony F. Heinz, Dietmar Mller a......nny Krayzelburg is moving his shoulders now, after undergoing two shoulder operations. Or they could tell her how Klete Keller is shifting his weight and how he might adjust it to increase his speed. "Simulations will help us identify and evaluate potential solutions that are feasible for each individual ath...Why some neonates need caffeine
...ere compared with a control group (11 neonates not undergoing caffeine therapy) matched for age and body mass. Neonates with neurological or cardiac disorders were excluded from the study. Results Two important findings were observed in this study. First, for all neonates, the decrease in minute ventilation ...Gene expression patterns may help predict risk and progression of prostate cancer
...y altered that it resembled a cancer field effect, undergoing genetic changes similar to prostate cancer, even though it was morphologically benign tissue. "It appears that genetic alterations in the prostate occur in parts of the gland that otherwise look benign," said Joel Nelson, M.D., professor and...JCI Table of Contents, 15 July 2004
...hat have been implicated in patient bone loss when undergoing this treatment. While one PI called indinavir has...nd therefore able to prevent bone-loss in patients undergoing HAART, and the specific molecular mechanisms uncovered here may aid in understanding the side-effect...European researchers tackle mitosis
...and EMBL researchers will make movies of the cells undergoing division, using sophisticated microscopes developed by Rainer Pepperkok, Jan Ellenberg and Leica Microsystems. Several hundred thousand movies will be produced, filming each group of cells over a 48-hour period, to capture the full impact of silencin...Anti-cancer agent built from anti-inflammatory drug
...g cancer cells to self-destruct. The agent is now undergoing laboratory testing by the National Cancer Institut... tests. One of the derivatives, OSU 03012, is now undergoing toxicological and pharmacological testing by the NCI's RAID program. Data from these tests will help...Chemoradioimmunotherapy for advanced breast cancer: hope for the future?
... clear evidence that the treated tumour cells were undergoing significantly greater apoptosis than the untreated controls. Apoptosis was confirmed by the detection of activation of caspase-3-9 (an enzyme involved in apoptosis), inhibition of DNA synthesis and metabolic activity in the tumour cells and the forma...