Early dexamethasone exposure has long-term neurodevelopment, neuroendocrine effects
...y function in ventilator-dependent ELBW infants is undergoing significant modification towards more judicious treatment dexamethasone therapy is given less often and shorter courses are now used. The concern remains that little is known about dexamethasone effects on long-term neurodevelopment. For obvious re...Biologists ID defense mechanism of leading fungal pathogen
...mune systems, including AIDS patients and patients undergoing certain types of treatment for cancer. In cases where Candida infections spread to the bloodstream, mortality rates climb as high as 50 percent. Candida's defense against NO relies on enzymes called flavohemoglobins. Gustin's research involved a test...Common chemicals morphing into potential toxins in Arctic
... be travelling to remote regions of the planet and undergoing chemical reactions before building up in the food chain, says a new study from the University of Toronto. Until now, scientists had no idea why the persistent chemicals perfluorinated carboxylic acids (PFCAs) were present in remote areas such as th...Frogs muscle-in on 'wasting' process
...olic rate by about 90 per cent and unlike animals undergoing hibernation it does this while it's still warm," Dr Hudson says. "There are theories on how this happens, but hopefully our three-year research project will clarify these and define the genes and regulatory networks involved."...North Shore-LIJ research collaboration with Correlogic Systems to advance ovarian cancer blood test
...dden patterns approach and technology is currently undergoing extensive validation. The test has received worldw...of patients, North Shore-LIJ will invite all women undergoing specific gynecologic surgery, women at high risk who are not undergoing surgery, and women who have ...Brain development and puberty may be key factors in learning disorders
...the teenage brain is a formidable work-in-progress undergoing myriad changes. "If our hypothesis is correct, it suggests a strong need for early intervention and a potential for improving the abilities of individuals with learning difficulties," said Wright. "With early identification of children with languag...Therapeutic cloning may be permitted at Newcastle University
...ggs would be donated for this research by patients undergoing treatment for fertility at the Center. Professor Murdoch said, "we are very grateful to all those patients who help with this research. Although the studies will not directly help them, they are playing a vital role in helping other patients." ...Gene therapy tested to protect bone marrow during chemotherapy
...p protect the bone marrow cells of cancer patients undergoing chemotherapy. Stanton Gerson, M.D., professor of medicine, has been leading the effort to introduce a gene into bone marrow cells that would protect the cells against the debilitating effects of chemo, thereby helping the patients ...Other Highlights in the June 2 JNCI
...e biopsy in a cohort of 205 breast cancer patients undergoing breast cancer surgery that included sentinel lymph node biopsy and removal of the axillary lymph nodes. Based on their results, the authors conclude that "this study supports the concept that the sentinel lymph node should be carefully and intensel...First time in the U.S.: Saint Louis University tests third-generation vaccine against smallpox
...accine. Scientists hope another study vaccine, now undergoing its first testing in the United States at Saint Lo...essed. So, for example, if you are HIV-positive or undergoing chemotherapy for cancer, you shouldn't receive the currently licensed vaccine." Dr. Frey said this s...Taxanes may enhance immunity in breast cancer patients
...ms one year after completing therapy than do women undergoing similar treatments without taxanes a finding that turns conventional medical wisdom on its head. Researchers in the Ohio State University Comprehensive Cancer Center Arthur G. James Cancer Hospital and Richard J. Solove Research Institute studied 22...National Cancer Gene Therapy Foundation gives $4.0 million in research grants
...ity of life with reduced side effects for patients undergoing treatments. Every year, over a half million people die from cancer and another million are diagnosed with some form of the disease. Conventional therapies, including chemotherapy, surgery, and radiation, while having produced a measure of success w...Gene-based screen sorts cancer cases, say Stanford researchers
...the patient may be a candidate for novel therapies undergoing clinical trials. "New therapies are usually tested in people who have failed the standard therapy," Levy said. "If you know in advance who won't respond well, you can treat them more aggressively or include these patients in trials of the many promis...Research finds lawn chemicals raise cancer risk in Scottish terriers
...exposed Scottish terriers of similar age that were undergoing treatment for unrelated ailments. "We found that the occurrence of bladder cancer was between four and seven times higher in the group exposed to herbicides," Glickman said. "The level of risk corresponded directly with exposure to these chemicals: T......, limiting its use to animal subjects and patients undergoing special types of brain surgery. The advantage of in vivo optical imaging compared to microelectrode recording is "seeing the forest instead of the trees," according to Casagrande. "You can see the global pattern of neurons turning off and on in resp...A new hypothesis about autoimmunity. Is it possible to be too clean?
...t signaling for their survival. Normally, T cells undergoing homeostatic expansion receive both signals to grow and signals to stay alive. Since the NOD mice cannot provide adequate amounts of these latter signals, their T cells proliferate furiously but do not survive long term. The NOD mouse's cells turn ove...St. Jude researchers create image of enzyme that orchestrates natural genetic engineering
...replication keeps the DNA stable, even while it is undergoing recombination. UvsW plays a major role in keeping DNA stable." There is evidence to suggest that two human helicases, Bloom and Werner, may have similar roles to those of UvsW in rescuing stalled replication forks. Mutations in these helicases cause...Survey reports fall in stem cell transplants for breast cancer
... wave of pessimism began to appear and the numbers undergoing high-dose chemotherapy began to drop. Most recent results remain ambiguous and the value of stem cell transplant in breast cancer still needs to be determined in selected categories. But, it might be an effective tool in treating some subsets of pati...Proven method of bone analysis may clarify human origins
...med to link modern quantitative methods, which are undergoing something of a revolution, with the analysis of a part of the skull we were interested in for a variety of reasons," said Lockwood. Kimbel adds, "The temporal bone has long been thought to have taxonomic and phylogenetic significance and seemed li......late waste and colliery shale. These products are undergoing development trials prior to being tested in the marketplace. Technium Chief Executive Steve Davies said: "The involvement of GRP provides us with the opportunity to develop world beating technologies that can be exported to provide solutions around t...