New study demonstrates bone protein can reverse kidney failure
... 300,000 kidney disease patients who are currently undergoing dialysis. "Dialysis is not really a treatment, it's just a means of survival until an opportunity for a transplant opens up," notes the study's senior author Raghu Kalluri, Ph.D., director of the Center for Matrix Biology at BIDMC and Associate Profe...Researchers find new way to trigger self-destruction of certain cancer cells
...K1 and inactivates it. This prevents the cell from undergoing apoptosis. The investigators also found that the stress caused by rapamycin requires the presence of a protein called 4E-BP1. This protein stops the cell from using use some types of mRNA (the "decoded" form of DNA) to make proteins, including surviv...Artificial organ research findings presented by University of Pittsburgh researchers
...on a temporary basis during healing. The device is undergoing extensive testing in animal models and is being developed commercially by a spin-off company, ALung Technologies Inc. Late last year, Pittsburgh researchers partnered with U.S. Army scientists on a project to evaluate the merit of the device for use ...Critical Therapeutics launches Phase I clinical trial of anti-inflammatory compound
...l to prevent and reverse complications in patients undergoing serious operations or multi-organ failure associated with life- threatening acute conditions including shock, myocardial infarction, acute pancreatitis, burns, stroke or acute drug allergies. Approximately $180 billion is spent each year to treat p...European Society of Human Reproduction & Embryology annual meeting
...d in a test tube is the procedure safe? Do women undergoing IVF still have a good chance of a baby if they have only one embryo transferred? Is there a link between polycystic ovaries and lesbians? Does abstaining from sex mean men have a better chance of success with assisted reproduction? What is the ass...Brookhaven Lab & Battelle collaborate on research that may lead to novel anti-microbial drugs
...ed, such as those with cancer or AIDS, or patients undergoing immunosuppressive therapies for organ transplantation or for the treatment of diseases such as multiple sclerosis and psoriasis. As a first step in reaching this goal of developing new drugs, Brookhaven biologist Maria Bewley will use the National Sy...Breakthrough in fight against infection misery
...fectious complication, which plagues many patients undergoing long-term bladder catheterisation. "It is estimated that some 400 million urinary catheters are used world-wide each year, and everyone who is catheterised for a month or more can expect to suffer an infection," explained Dr Stickler. "About half of ...Gene therapy may be a cure for post-radical prostatectomy erectile dysfunction
...apy to be used as a prophylactic treatment for men undergoing radical prostatectomy. Radical prostatectomy is used to treat the early stages of prostate cancer by surgically removing the prostate gland and surrounding tissue. The procedure has a success rate of 70 to 85 percent. A high percentage of patients ex...Scientists observe nanosize microtubules 'treadmilling' across plant cells
...is that almost all the microtubules we can see are undergoing a treadmilling motility." The way protein subunits are added and removed from a microtubule also proved interesting, Ehrhardt said: "It isn't the case that they are being smoothly added to the growing end and smoothly removed from the shrinking end. ...Missing protein is double-edged sword in cancer development
...entrosome duplication. Cells undergoing normal division have two centrosomes. Leone and his colleagues believe that E2F3 keeps this number in check. In the current study, about 60 percent of E2F3-deficient mouse cells had more ...St. Jude researchers use DNA chips to determine how leukemia cells respond to different drugs
... were identified in the leukemia cells of children undergoing chemotherapy for acute lymphoblastic leukemia (ALL). The researchers say this finding is a significant step in the emerging field of pharmacogenomicsthe study of a persons entire set of genes in order to determine which ones control that individuals...A kindler, gentler cut for LASIK
...LASIK eye surgery but who are still hesitant about undergoing the knife, a new laser-only surgical method developed at the University of Michigan may help reduce complications and improve overall results of the popular elective surgeryall while making the procedure less squeamish for the faint of heart. Accordi...New drugs restore immune response blocked by hepatitis C virus in human cells
... efficacy." Protease inhibitors, which are already undergoing clinical trials as therapies to treat chronic hepatitis C infections, target the enzymatic activity of the viral protease. Protease, an enzyme that can split a protein into component peptides, is required to process viral proteins into their function...Northwestern receives $5.65 million for reproductive research
...on of egg or oocyte banks, which would allow women undergoing chemotherapy to preserve their reproductive potential. Mature eggs that are frozen cannot be used for infertility treatments because they are destroyed in the freezing process. Immature eggs can be frozen, but they need an artificial environment that...The structure behind the switch
...m being IgM to being IgG or IgA or IgE or IgD. By undergoing this so-called class switch, Lieber explains, the body can send "the same antibody missile to different areas of the body." The switch is made by cutting the DNA so that the code for IgM and any of the other class types that might precede the desired...In vitro fertilization may be linked to bladder defects
... findings should not alone discourage couples from undergoing IVF." Exstrophy-epispadias complex, which is comprised of defects of the bladder, pelvic bones, urethra, and genitals, occurs in approximately four out of every 100,000 live births. Applying this incidence data to the 112,127 children who were born t...Gene that drives cells to commit suicide also plays key role in development of skeletal muscle
...aling pathways in the cell. However, in myoblasts undergoing differentiation, a different, unknown enzyme places phosphate molecules onto FKHR. This normally controls the activity of FKHR and the rate of myoblast fusion. Its somewhat like pushing a button on a machine when its in different parts of the same f...Alliance for Cancer Gene Therapy announces $1.5 million in national grants to young investigators
...ity of life with reduced side effects for patients undergoing treatments. Every year, over a half million people die from cancer and another million are diagnosed with some form of the disease. Conventional therapies, including chemotherapy, surgery, and radiation, while having produced a measure of success...Dyslexic children`s brains operate more like those of normal readers following training
...brains of dyslexic children can be rewired - after undergoing intensive remediation training - to function more like those found in normal readers. The training program, which is designed to help dyslexics understand rapidly changing sounds that are the building blocks of language, helped the participants becom......ect against blood loss and transfusion in patients undergoing cardiac surgery. They enrolled 517 cardiac surgery patients in the study, 26 of whom turned out to have one copy of the factor V Leiden gene (and one normal factor V gene). By measuring multiple variables and performing statistical comparisons, the ...