New Sensor Provides First Instant Test For Toxic E. coli Organism
...nd Cheng -- binds the bacteria toxin. The backbone underlying this surface is the color-changing signaling system described by Bednarski and Charych. The Biomolecular Materials Program focuses on adapting nature's biologicalsystems to problems outside the living organism. In this case says Stevens, "Weh......itutions are converging on an understanding of the underlying mechanismresponsible for more than a half-dozen debilitating neurodegenerative diseases.Among the movement disorders involved are Huntington's disease andMachado-Joseph disease, less well known than Huntington's but perhaps as common.The findings wil...Discovery Of Genetic Pathways May Provide New Ways To Combat Candida Infections
...new study has uncovered the genetic wiring diagram underlying the infectiousness of Candida albicans, a fungus t...orm to filamentous forms. When the wiring diagram underlying this switch is inactivated, Candida infections are no longer deadly in mice. The implications of the...Researchers Find Association Between Alzheimer's Gene And Mental Impairment After Cardiac Surgery
...be at higher risk, in more than half the cases the underlying predispositionfor impairment is not known. In the study patients were given a battery of cognitive tests prior tosurgery and 6 weeks after surgery. The study also showed that a higher level of education is protectiveof cognitive decline. "We don't...NIDR Supports Total Genome Studies Of Major Oral Pathogens
...a chronic inflammatory infection of thegingiva and underlying bony tissues, and there is no effective prevention. Treatment involves surgical or mechanical removal of diseased tissues ("scalingand planing"), coupled with antibiotic therapy. Despite such extensivetreatment, the condition can still recur. Witho...DNA Helps Track Origins Of Growing Blight Problem
... factor in the Irish potato famine of 1845-46."The underlying principle in all of this is that neither borders, nordistances, can prevent diseases from spreading," he concludes. His research is funded by the B.C. Potato Growers Associationand is being conducted in collaboration with the provinci......ugh APECED as such is not a common disease, the underlying mechanism of this disease may be common to other autoimmune conditions, such as diabetes and rheumatoid arthritis, disease with important clinical as well as socio-economical implications....Scientists Identify A Novel Mitotic Regulatory Mechanism
...directed protein kinases. The overall principle underlying cell cycle regulation is the appropriately timed structural modification of proteins through kinase and phosphatase mediated phosphorylation/ dephosphorylation, and protein degradation. The new results of the research teams suggest reg...Genetic "Short Circuit" Leads To Cleft Palate
... thinks that it is still premature to pinpoint the underlying causes of cleft palate from human studies. "It is apparent from studying complex disorders like cleft palate, that simply identifying genetic differences between healthy and affected individuals is not enough to explain the cause of the disorder," s...Early Career Development Grants Foster Faculty Research And Education
...lopand make sense of mathematical models and their underlying structures, and how these relate to various possible applications. The study will focus on classroom learning where students have access to calculators, computers, and related laboratory equipment. Her work seeks insights into the roles and abiliti...Genetic Risk Factors For Anorexia Nervosa Sought
... fromthose samples to identify the genetic factors underlying anorexia. The mostlikely finding, Berrettini says, is that several interacting susceptibilitygenes are involved. Treatments available for anorexia are limited in their long-termeffectiveness, and patients are prone to relapse. Berrettini s...Cellular 'Short Circuit' Causes Insulin Resistance
... -- Future treatments for diabetes may correct the underlying causes of this prevalent metabolic disorder rather than just treat its symptoms. An important step in this direction has been made by Prof. Yehiel Zick of the Weizmann Institute's Molecular Cell Biology Department. In a study reported in the Novem...Memorial Sloan-Kettering Investigators
...esearchers delving into the fundamental mechanisms underlying one formof leukemia have learned how to interfere with the genetic changes that lead tothis potentially fatal type of cancer. In laboratory studies, the investigatorsidentified a combination of drugs that turn on proteins called transcriptionfactors......periment in one area -- say biology -- has thesame underlying logic as a well designed experiment in some other area, such asphysics or social studies," Klahr explains. By helping children to acquire a reasoning skill fundamental toscientific experimentation, teachers may be able to help their f..."Genetic Factors Influencing Cholesterol Response To Diet"
...This result strongly suggests that genetic factors underlying thepredisposition to pattern B also influence the LDL response to reduced fatintake. Dietary fat-induced changes in LDL particle size and density phenotypesare linked to candidate genetic loci. LDL particle size and density areinfluenced by...When To Reproduce? It's All In The Timing
...rcent or less. These studies have used an underlying assumption that reproductivecells, or gametes, are...on and Serraodelved into the biochemical mechanism underlying gamete release. Levels ofdissolved inorganic carbon such as carbon dioxide and bicarbonate, theyhypo...Drug-Resistant Infection Once Found Only In Hospitals Now Present In Community
...frequent antibiotic use, history of intubation, an underlying chronic disorder,presence of a catheter, history of any surgical procedure, or household contactwith a person who has identified risk factors. The researchers also found interesting differences between hospital-acquired andcommunity-acquired MRSA inf...Women Can Inherit Drinking Problem Too, Study Finds
...ts in the generalpopulation could be attributed to underlying genetic differences. "As a point of comparison, s...ion of the difference in risk can be attributed to underlying geneticdifferences." Heath hopes the study will serve as a warning sign for women who know they ha...Water Quality In Indiana's White River Basin Affected By Urban And Agricultural Activities
...rams per liter. Surficial sand and gravel aquifers underlying cropland had high nitrate concentrations. Samples from 17 percent of shallow monitoring wells in this setting exceeded the Federal drinking-water standard. However, deeper wells (25 to 50 feet below the water table) in these unconfined aquifers typic......umanbone disease, with the hope of discovering the underlying causes and developingnovel treatments. The success of the procedure, reported in the April 15th issue of The Journal ofClinical Investigation, lies in the special characteristics of cells in the bonemarrow called stromal cells. The stromal cells ha...